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The overall aim of this thesis work is to characterize artificial biomolecular motors, specifically the Lawnmower, a motor based on the burn bridges mechanism, and the Tumbleweed, a protein motor that employs ligand specific DNA-proteins binding to step along DNA. An overview of their operational principles is given, and initial results of our studies are presented, along with a review of currentl
Background: Deliberate self-harm (DSH) is a common behavior in psychiatric populations. However, little is known regarding how DSH impacts daily life. The concept of functional disability, adopted by the World Health Organization (WHO), refers to the impact of disorders on six domains of daily functioning. The aim of the current study was to explore the functional disability of psychiatric patient
This audio paper draws on analysis of a case study within the field of artistic research. In summer 2018, the project sent poet Gunnar D. Hansson, composer Anders Hultqvist and ecological sound artists Stefan Östersjö and Halla Steinunn Stefánsdóttir on a search for the sounds of the book Tapeshavet (Hansson, 2017). The work links to the author’s Activation Series, which employs the artistic metho
This presentation discusses two examples of participatory sense-making, that fall within the ecological-enactive trajectory of my artistic research. The first work is Tapeshavet, a collaboration between composer Anders Hultqvist, poet Gunnar D. Hansson and ecological sound artist Stefan Östersjö and I, with the first output premiered at GAS festival in Sweden in autumn 2018 and a larger work set f
BACKGROUND: Bladder cancers have high total mutation burdens resulting in genomic diversity and intra-and inter-tumor heterogeneity that may impact the diversity of gene expression, biologic aggressiveness, and potentially response to therapy. To compare bladder cancers among patients, an organizational structure is necessary that describes the tumor at the histologic and molecular level. These 'm
Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasound-guided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrosp
Background: Patients in intensive care units (ICUs) are among the most vulnerable, and they require support to start their recovery. The design of the patient area in the ICU can play a prominent role in both the quality of care and patients’ recovery. The lighting environment has the opportunity to restore and strengthen the natural human circadian rhythm and health. Aim: To evaluate patients’ se
Purpose: To evaluate urinary continence (UC) recovery and oncological outcomes in different risk-groups after robot-assisted radical prostatectomy (RALP) and open retropubic radical prostatectomy (RRP). Patients and methods: We analysed 2650 men with prostate cancer from seven open (n = 805) and seven robotic (n = 1845) Swedish centres between 2008 and 2011 in a prospective non-randomised trial, L
Dagens situation med begränsad kapacitet i elnätet kan leda till allvarliga problem. Eftersom ”först-till-kvarn” gäller finns det risk för att internationella företag konkurrerar ut lokala verksamheter.
Background: Infertility is a well-known sequela of cancer treatment. Despite guidelines recommending early discussions about risk of fertility impairment and fertility preservation options, not all patients of reproductive age receive such information. Aims: This study aimed to investigate young adult cancer patients’ receipt of fertility-related information and use of fertility preservation, and
The benefit of surgery in high-grade gastroenteropancreatic neuroendocrine neoplasms (GEP NEN) and mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) is uncertain. The present study aimed to investigate outcomes after tumour surgery in patients with high-grade (Ki-67 > 20%) GEP NEN or MiNEN stage I-III or stage IV. We analysed data from patients treated in the period 2007-2015 at eight Nord
Crocodilians are the closest living relatives of birds and share many ecological challenges with mammalian apex predators. They evolved perception pathways that share similarities with both taxa, birds and mammals. Due to their position in the tree of life, crocodilians therefore represent a promising intermediate model for comparative research. In this review, the different modalities of percepti
With global efforts in reducing energy consumption, house manufacturers are seeking use of new materials and design solutions. However, some believe this will increase the risk of mould. One way to assess the mould risk is to use a hygrothermal software for simulating the climate envelopes’ moisture performance. But as with all simulation, the quality of the output can never be better than the qua
987/5000En omfattande ram för en hållbar renoveringsprocess med en helhetssyn på renovering har utvecklats med beaktande av områdena: teknik, miljö, ekonomi, sociala värden och arkitektur och kulturhistorisk miljö. Ramverket beskriver aktiviteter som ska genomföras i olika steg i processen, samt kartlägger vem som kommer att ansvara för och utföra dessa aktiviteter. Ramverket hänvisar till tillgänA comprehensive framework for a sustainable renovation process with a holistic approach to renovation has been developed, taking into consideration the areas: technology, environment, economy, social values, and architecture and cultural historical environment. The framework describes activities that should be carried out at different stages of the process, as well as charting who will be responsi
In Europe, all new houses built require an energy declaration showing the expected energy consumption during use. However, there is often a discrepancy between the calculated and the actual energy consumption. Some claim that in general the difference is on the positive side for wooden buildings, with real energy consumption being lower than predicted. This could be an effect of thorough and long-
Inom byggsektorn måste byggnader vara mer energieffektiva än någonsin tidigare. Tuffare byggregler kräver allt mer exakta energibehovsberäkningar för att säkerställa byggnadens operativa prestanda. Överföringsvärmeöverföringsförluster genom byggnadens kuvert spelar en nyckelroll i byggnadens totala energiprestanda. Att underskatta dessa förluster kan leda till att energikraven inte uppfylls. För nWithin the construction sector buildings are required to be more energy efficient than ever before. Tougher building regulations require ever more accurate energy demand calculations to ensure a building’s operational performance. Transmission heat transfer losses through a building’s envelope play a key role in the overall energy performance of the building. Underestimating these losses may lead
