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The Great Dun Fell experiment 1995 : An overview

During March and April of 1995 a major international field project was conducted at the UMIST field station site on Great Dun Fell in Cumbria, Northern England. The hill cap cloud which frequently envelopes this site was used as a natural flow through reactor to examine the sensitivity of the cloud microphysics to the aerosol entering the cloud and also to investigate the effects of the cloud in c

High sensitivity elemental analysis methodology for upper tropospheric aerosol

In this study, a sampling and analysis tool for aerosol particles has been developed. Its purpose is to characterize upper tropospheric aerosols, where concentrations are low. Since measurements will be made from an airplane, a time resolution of one hour is desirable. These conditions require efficient sampling and analysis with low detection limits. To accomplish this, our sampler uses impaction

Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function

Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system (CNS). Here we investigated the effects of acute and chronic ethanol exposure and withdrawal from chronic ethanol exposure on glymphatic function, which is a brain-wide metabolite clearance system connected to the peripheral lymphatic system. Acute and chronic exposure to 1.5 g/kg (binge

Storage and Utilization of the Waste Heat from National Veterinary Institute (SVA), Uppsala, Sweden

The incineration furnace at National Veterinary Institute (SVA) in Uppsala, Sweden, generates a large amount of waste heat. Some of this heat is partially recovered and is used for heating one of the main buildings during the furnace operation. However, around 2,000 MWh is wasted annually due to unavailability of any storage system. This work studies in detail four different solutions to utilize t

ApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice

AIMS/HYPOTHESIS: Finding new treatment alternatives for individuals with diabetes with severe insulin resistance is highly desired. To identify novel mechanisms that improve glucose uptake in skeletal muscle, independently from insulin levels and signalling, we have explored the therapeutic potential of a short peptide sequence, RG54, derived from apolipoprotein A-I (ApoA-I).METHODS: INS-1E rat cl

The New MAX IV Gun Test Stand

The gun test stand from MAX-Lab has been upgraded and moved to a new facility at the MAX IV Laboratory. The new test stand will reuse parts of the equipment from the old test stand but a number of improvements to the setup are be made. In this paper we report on the design of the new gun test stand, research plans in the near future as well as planned and possible future research topics..

The size dependent composition of fog droplets

The size dependency of fog droplet concentration and composition was studied using newly developed droplet impactors during the CHEMDROP campaign in the Po Valley (Italy). A strong size dependency of solute concentrations was measured during several fog episodes. The ionic strength of the droplet solutions varies as a function of droplet diameter, showing maximum values in the 9-19 μm diameter ran

Bone marrow eosinophils in plasma cell disorders

In experimental studies, eosinophils have been shown to promote the survival, proliferation, and retention of plasma cells in the bone marrow (BM). The clinical significance of eosinophils in plasma cell disorders (PCDs) in humans is largely unknown. This study focuses on the frequency and phenotype of eosinophils in the BM and peripheral blood (PB) in patients with untreated PCD compared with hea

Visual field shape and foraging ecology in diurnal raptors

Birds, particularly raptors, are believed to forage primarily using visual cues. However, raptor foraging tactics are highly diverse – from chasing mobile prey to scavenging – which may reflect adaptations of their visual systems. To investigate this, we studied the visual field configuration of 15 species of diurnal Accipitriformes that differ in such tactics, first focusing on the binocular fiel

Dopaminergic effect on non-motor symptoms in late stage Parkinson's disease

Background: Non-motor symptoms (NMS) are common in late stage Parkinson's disease (PD), as the frequency and severity of most of these symptoms increase with advancing disease. Objective: To assess effect of dopaminergic therapy on NMS in late stage PD and to investigate relationships between dopaminergic effect on NMS and on motor function. Method: Thirty PD patients in Hoehn and Yahr (HY) stages

Regulating recyclability under the ecodesign directive : How can we achieve synergies between waste and product policies for electric and electronic equipment to promote recycling?

Introduction: The interaction between different product policies will be crucial for the further advancement of a coherent product policy framework. The Commission has stated that ‘the complex and interlocking approach needed to build a resource-efficient Europe can only be achieved with a policy mix that optimizes synergies and addresses trade-offs between different areas and policies’. In the co

Present and future challenges for Europe’s environmental product policy

Concerns about the environmental effects of the ‘throwaway society’ are increasingly influencing policy-making and regulatory action in the EU. The Seventh Environment Action Programme, which aims to guide European environmental policy, sets out a long-term vision for the EU that requires a major shift in the way economic activities are conducted: In 2050, we live well, within the planet’s ecologi

Ion-beam thermography analysis of the H2SO4-(NH4)2SO4 system in aerosol samples

Ion-beam thermography (IBT) is used to determine the chemical composition of atmospheric aerosols. The aerosols are analyZed by a combination of four ion-beam techniques PIXE, PESA, pNRA and cPESA during thermography. These techniques monitor the concentrations of the available elements during the stepwise heating of the sample. For each element a thermogram, i.e., the concentration vs. temperatur

A closure study of sub-micrometer aerosol particle hygroscopic behaviour

The hygroscopic properties of sub-micrometer aerosol particles were studied in connection with a ground-based cloud experiment at Great Dun Fell, in northern England in 1995. Hygroscopic diameter growth factors were measured with a Tandem Differential Mobility Analyser (TDMA) for dry particle diameters between 35 and 265 nm at one of the sites upwind of the orographic cloud. An external mixture co

A relative humidity processing method for the sampling of aerosol particles with low growth‐ability

A method for the fractionation of aerosol particles with respect to size and ability to grow with an increased relative humidity has been developed. The system consists of cascade impactors, diffusion driers, a humidifier and a temperature stabiliser. Diffusion driers were designed and the vapour penetration was modelled below 20%. A humidifier which can be operated with an output relative humidit