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Suppression of kindling epileptogenesis in rats by intrahippocampal cholinergic grafts

Selective immunolesioning of the basal forebrain cholinergic system by 192 IgG-saporin, which leads to a dramatic loss of the cholinergic innervation in cortical and hippocampal regions, facilitates the development of hippocampal kindling in rats. The aim of the present study was to explore whether grafted cholinergic neurones are able to reverse the lesion-induced increase of seizure susceptibili

Additions to the spectrum and energy levels and a critical compilation of helium-like and hydrogen-like boron, BIV and BV

Using beam-foil spectroscopy, we have observed several new lines in the B IV and B V spectra. This experimental work was combined with theoretical calculations using ab initio and semi-empirical techniques. We have also critically evaluated all previous and recent experimental and theoretical data for these spectra. Complete data on wavelengths and energy levels based on this analysis are tabulate

Comparison of supercritical carbon dioxide and ethyl acetate extraction of alkylresorcinols from wheat and rye

In this study, the application of supercritical carbon dioxide extraction of alkylresorcinols (AR) was quantitatively and qualitatively compared to a commonly used ethyl acetate extraction procedure. No difference in total AR content, relative homolog composition or total extract yield was found between the two extraction methods. Ethyl acetate extraction of intact wheat and rye kernels yielded on

Feedback control of Purkinje cell activity by the cerebello-olivary pathway.

The pathway from the deep cerebellar nuclei to the inferior olive, the source of the climbing fibre input to the cerebellum, inhibits olivary transmission. As climbing fibre activity can depress the background firing of the Purkinje cells, it was suggested that nucleo-olivary (N–O) inhibition is a negative feedback mechanism for regulating Purkinje cell excitability. This suggestion was investigat

The peroxisome proliferator-induced cytosolic type I Acyl-CoA thioesterase (CTE-I) is a serine-histidine-aspartic acid alpha/beta hydrolase

Long-chain acyl-CoA thioesterases hydrolyze longchain acyl-CoAs to the corresponding free fatty acid and CoASH and may therefore play important roles in regulation of lipid metabolism. We have recently cloned four members of a highly conserved acyl-CoA thioesterase multigene family expressed in cytosol (CTE-I), mitochondria (MTE-I), and peroxisomes (PTE-Ia and -Ib), all of which are regulated via

A nucleophilic substitution reaction performed in different types of self-assembly structures

A nucleophilic substitution reaction between 4-tert-butylbenzyl bromide and potassium iodide has been performed in oil-in-water microemulsions based on various C12Em surfactants, i.e., dodecyl ethoxylate with m number of oxyethylene units. The reaction kinetics was compared with the kinetics of reactions performed in other self-assembly structures based on very similar surfactants and in homogeneo

Occurrence, conformational features and amino acid propensities for the pi-helix.

The most abundant helix type in proteins is the alpha-helix, accounting for about 31% of amino acid secondary structure states, while the 3(10)-helix accounts for about 4%. The pi-helix appears to be extremely rare and is considered to be unstable. Existing secondary structure definition methods find very few within the Protein Data Bank. Using an improved pi-helix definition algorithm to search a

Extreme value modelling of storm damage in Swedish forests

Forests cover about 56% of the land area in Sweden and forest damage due to strong winds has been a recurring problem. In this paper we analyse recorded storm damage in Swedish forests for the years 1965-2007. During the period 48 individual storm events with a total damage of 164 Mm(3) have been reported with the severe storm on 8 to 9 January 2005, as the worst with 70 Mm(3) damaged forest. For

Population density and species composition of moss-living tardigrades in a boreo-nemoral forest

This study investigates for the first time the tardigrade fauna in a variety of different mosses from a coniferous forest and an adjacent clear-cut area in southern Sweden. Tardigrades were found in a majority of the samples. Sixteen species were recorded, of which the cosmopolitan species Macrobiotus hufelandi was the far most common. Some mosses, particularly species with "wefts" growth form, co

Explicit and implicit methods in psychosocial occupational therapy

Sometimes the goal of a psychosocial occupational therapy intervention is not obvious for someone observing the process, and this may lead to misunderstandings as to the targeted outcomes for various occupational therapy methods. Summarizing features found in psychosocial occupational therapy practice, in textbooks, and in occupational therapy models, this paper proposes a simple structure for cha

A quantitative model of the domain structure of the photosynthetic membrane

A model is presented that gives a quantitative picture of the distribution of the photosynthetic components in the photosynthetic membrane of higher plants. A salient feature of the model is that most of the pigments are located in the grana where photosystem I and II carry out linear electron transport, whereas the stroma lamellae, which harbour

An Experimental Study of Liquid-Phase Heat Transfer in Multiport Minichannel Tubes

Heat transfer has been evaluated experimentally on the tube side of three different minichannel tubes, so-called multiport extruded (MPE) tubes, with different cross-section geometry. The objective was to find out which correlations, models, and relations should be used when predicting the performance of complete heat exchangers consisting of such tubes. The geometry of the tube channels or ducts

Prognostic importance of the soluble plasminogen activator receptor, suPAR, in plasma from rectal cancer patients

Colorectal cancer is one of the most common tumour types with approximately one third of the tumours located within the rectum. Rectal cancer differs somewhat from colon cancer, e.g. regarding the method of operation and the use of preoperative radiotherapy due to a tendency for local tumour recurrence. Proteolytic enzymes have been identified as key molecules in tumour invasion and metastasis, an

Runge-Kutta time discretizations of nonlinear dissipative evolution equations

Global error bounds are derived for Runge-Kutta time discretizations of fully nonlinear evolution equations governed by m-dissipative vector fields on Hilbert spaces. In contrast to earlier studies, the analysis presented here is not based on linearization procedures, but on the fully nonlinear framework of logarithmic Lipschitz constants in order to extend the classical B-convergence theory to in