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Neurogenesis, the process by which new neurons are formed, dramatically declines in the aging brain. A research group from Lund Stem Cell Center have published a study that sheds light on the different factors contributing to this loss, particularly the role of inflammation. “One of the focuses of our research is on what goes wrong in the brain during aging” explains Henrik Ahlenius, principle inv

https://www.medicine.lu.se/article/researchers-identify-novel-regulator-neurogenesis-aged-brain - 2025-12-09

A sun drenched day in the allies of Västra Hamnen. A whirlwind of black and white tails, snouts and barks are on duty at the townhouse door. Dog dad, Professor of Immunology Tomas Leanderson, hushes, admonishes, welcomes into the kitchen table and coffee. In a few days, this rare specimen of the old kind of professor at the Faculty of Medicine will be a free man, after a life-long love affair with

https://www.medicine.lu.se/article/one-last-ones-out-old-school-professors - 2025-12-09

High blood pressure damages our blood vessels. It also damages our heart, our brain and our kidneys. A high blood pressure increases the risk of suffering a heart attack and stroke. However, it is not known exactly why a high blood pressure is so dangerous. – The reason is that we have effective antihypertensive medications. So why bother how pressure-induced damage occurs. We feel that this posit

https://www.medicine.lu.se/article/high-blood-pressure-bloody-serious - 2025-12-09

A person who carries the mutant gene will at some point in his or her life develop the deadly Huntington's disease. This brain disease can be inherited from generation to generation and begins insidiously, making it increasingly difficult to regulate emotions, thoughts, then movements. There is no treatment that slows down the disease. But Huntington researcher and psychiatrist Åsa Petersén works

https://www.medicine.lu.se/article/huntingtons-disease-fascinating-and-touching-mystery - 2025-12-09

Pulmonary fibrosis is a severe and life shortening chronic condition. Although most people experience mild symptoms of COVID-19, some patients develop serious and life-threatening conditions with severe lung damage. In order to influence the outcome of the disease, lung researchers in Lund are currently establishing methods to identify risk groups at an early stage. A significantly altered lung st

https://www.medicine.lu.se/article/identification-prognostic-markers-development-chronic-lung-fibrosis-covid-19-patients - 2025-12-09

A new joint report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) presents the largest venture ever on precision medicine in diabetes. The report includes a detailed overview and roadmap for how this new approach to diabetes medicine can be evaluated and implemented into clinical practice. The role of precision diabetes medicine will be t

https://www.medicine.lu.se/article/roadmap-precision-medicine-diabetes-care - 2025-12-09

Adriana Sanna defended a thesis on 20 May, Shamik Mitra on 26 May and Rita Cabrita on 10 June. How come there were three at almost the same time?“All three were admitted simultaneously through MELGEN, a European network that has Marie Curie funding. My trio of doctoral students were amongst the 17 in the network. As all doctoral students were admitted through a European-wide process, they were exc

https://www.medicine.lu.se/article/three-doctoral-thesis-defences-1-week - 2025-12-09

Researchers from Lund Stem Cell Center have identified a novel target for the expansion of human blood stem cells ex vivo and shed light on the mechanism of action of a stem cell promoting molecule, currently in phase II clinical trials. Hematopoietic stem cell transplantation is a curative therapy for many patients suffering from life threatening blood disorders. This treatment is currently limit

https://www.medicine.lu.se/article/new-insights-ex-vivo-expansion-transplantable-human-blood-stem-cells - 2025-12-09

Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer’s disease pathology. The study has been published in Stem Cell Reports. In Alzheimer’s disease the hippocampus, a brain structure that regulates motivation, emotion, learning, and memory, is severely a

https://www.medicine.lu.se/article/new-research-paves-way-developing-therapies-could-slow-down-alzheimers - 2025-12-09

Researchers at Lund University in Sweden have discovered a new method to treat human herpes viruses. The new broad-spectrum method targets physical properties in the genome of the virus rather than viral proteins, which have previously been targeted. The treatment consists of new molecules that penetrate the protein shell of the virus and prevent genes from leaving the virus to infect the cell. It

https://www.medicine.lu.se/article/antiviral-method-against-herpes-paves-way-combatting-incurable-viral-infections - 2025-12-09

A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer’s disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the Journal of the American Medical Association (JAMA) and simultaneously presented at

https://www.medicine.lu.se/article/new-blood-test-shows-great-promise-diagnosis-alzheimers-disease - 2025-12-09

A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. The new study has been published in the July issue of Advanced Therapeutics. Lung tumors are often difficult to remove using current surgical techniques due to their location in

https://www.medicine.lu.se/article/new-promising-treatment-uses-smart-nanoparticles-target-lung-cancer - 2025-12-09

Around 20,000 people have been diagnosed with Parkinson's disease in Sweden. Today, there is no imaging method of changes in the brain that are believed to cause the disease. Researchers at Skåne University Hospital and Lund University have received nearly SEK 7 million from the Michael J Fox Foundation to develop an imaging technique that can more accurately detect and track the development of Pa

https://www.medicine.lu.se/article/millions-michael-j-fox-foundation-improve-diagnosis-parkinsons - 2025-12-09

Prof. Johan Jakobsson and Assoc. Prof. Agnete Kirkeby from Lund Stem Cell Center and University of Copenhagen, along with co-applicants Prof. Roger Barker from Cambridge, UK and Assoc. Prof. Molly Hammell from Cold Spring Harbour Laboratory, US, have been awarded a prestigious grant from the Aligning Science Across Parkinson’s initiative. Using this funding they will investigate the role transposa

https://www.medicine.lu.se/article/researchers-investigate-role-transposable-elements-neuroinflammation-and-parkinsons-disease - 2025-12-09

The University Board has today decided to recommend the dean of the Faculty of Medicine, Erik Renström, as the new vice-chancellor of Lund University for the term of office 2021 to 2026. "This is a big step. I am humble and it is with deep respect I am looking forward to this task", comments Erik Renström.He is also highlighting that the definitive decision from the Swedish Government is yet not t

https://www.medicine.lu.se/article/erik-renstrom-proposed-new-vice-chancellor - 2025-12-09

Johan Richter's research has resulted in the successful development of gene therapy for the hereditary disease malignant infantile osteopetrosis. For the past few years, the research group has established a collaboration with an American biotech company and all the permits needed to start a clinical trial have now been obtained. Every year in Sweden a child is born with the unusual skeletal diseas

https://www.medicine.lu.se/article/successful-biotech-collaboration-brings-gene-therapy-project-clinic - 2025-12-09

Metformin is the first-line drug that can lower blood sugar levels in type 2 diabetes patients. One third of patients do not respond to metformin treatment and 5 per cent experience serious side effects, which is the reason many choose to stop medicating. Researchers at Lund University in Sweden have now identified biomarkers that can show in advance how the patient will respond to metformin treat

https://www.medicine.lu.se/article/metformin-type-2-diabetes-patients-or-not-researchers-now-have-answer - 2025-12-09

A large proportion of our elite athletes are suffering psychological distress during the COVID-19 pandemic, with more women than men reporting adverse reactions. This is demonstrated by the study Psychological Distress and Problem Gambling in Elite Athletes during COVID-19 Restrictions: A Web Survey in Top Leagues of Three Sports during the Pandemic, published in the International Journal of Envir

https://www.medicine.lu.se/article/many-elite-athletes-feeling-psychological-distress-during-pandemic - 2025-12-09

Lund University researchers have developed an analytical model that can effectively detect and identify gene mutations in breast tumours. In the study, which is the largest of its kind anywhere in the world, they are now reporting results from 3,200 breast cancer patients. To assist them, they have utilised a technique known as RNA sequencing, a sensitive and precise tool that, while it is slowly

https://www.medicine.lu.se/article/new-analytical-method-benefits-breast-cancer-patients - 2025-12-09

A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine. Every year, about 20 children in Sweden are diagnosed with neuroblastoma, an aggressive cancer of the nervous system that most frequently arises in the adrenal glands.

https://www.medicine.lu.se/article/promising-treatment-aggressive-childhood-cancer - 2025-12-09