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Thesis Defence Interview – Daniela Grassi

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 20 April 2020 Daniela Grassi defends her thesis on Thursday 23rd April. Photo: Kennet Ruona With a research focus on the development and application of in vitro models to study human brain evolution and disease, PhD student Daniela Grassi will be defending her thesis on Thursday 23rd of April 2020. Here, Daniela tell

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-daniela-grassi - 2025-01-10

Thesis Defence Interview – Carla Azevedo

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 27 April 2020 Carla Azevedo defends her thesis on Thursday 30th April Carla Azevedo is set to defend her PhD thesis titled “Oligodendroglial (dys)function in alpha-synucleinopathies” on Thursday 30th of April. Here, Carla answers a few questions about her PhD journey at Lund Stem Cell Center, researching in the iPSC

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-carla-azevedo - 2025-01-10

Autophagy and the treatment of Huntington disease: timing is key

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 8 May 2020 Accumulating levels of protein aggregates characteristic of Huntington disease (left) can be reduced by boosting autophagy (right). Image source: Karolina Pircs. Huntington disease is fatal inherited brain disorder, usually emerging during mid-life. Although there is currently no known cure, the Molecular

https://www.stemcellcenter.lu.se/article/autophagy-and-treatment-huntington-disease-timing-key - 2025-01-10

New method provides unique insight into the development of the human brain

By Agata [dot] Garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 25 May 2020 Image of a human embryo surrounded by placenta, around 7 weeks of age. Image credit Hill, M.A. (2020, May 18) Embryology  Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brai

https://www.stemcellcenter.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-01-10

Researchers identify a novel regulator of neurogenesis in the aged brain

By Alexander [dot] Doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 29 May 2020 Neuroblasts (green) in the aged brain traveling from the subventricular zone (SVZ) to the olfactory bulb (OB) via the rostral migratory stream (RMS). Proliferating cells are shown in red. Image from Jonas Fritze. Neurogenesis, the process by which new neurons are formed, dramatically declines in the aging

https://www.stemcellcenter.lu.se/article/researchers-identify-novel-regulator-neurogenesis-aged-brain - 2025-01-10

Thesis Defence Interview – Franziska Olm

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 11 June 2020 Franziska Olm will defend her PhD thesis on Friday 12th June 2020 PhD student Franziska Olm has been developing a microfluidic-based acoustophoresis method to process stem cell preparations label-free, a technique with great research and clinical potential. In this interview, Franziska tells us about her

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-franziska-olm - 2025-01-10

New insights into the ex vivo expansion of transplantable human blood stem cells

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 25 June 2020 Postdoctoral researcher Agatheeswaran Subramaniam and PhD Student Kristijonas Žemaitis from the Stem Cell Regulators research group. Photo: Alexander Doyle Researchers from Lund Stem Cell Center have identified a novel target for the expansion of human blood stem cells ex vivo and shed light on the mecha

https://www.stemcellcenter.lu.se/article/new-insights-ex-vivo-expansion-transplantable-human-blood-stem-cells - 2025-01-10

Nanostraws used to deliver biomolecules to stem cells

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 18 August 2020 Electron microscopy image of hematopoietic stem/progenitor cell on top of nanostraws. Image credit: M. Hjort and L. Schmiderer Researchers from Lund University have developed a promising new method for delivering biomolecules into human blood stem cells using nanotechnology. With little to no detriment

https://www.stemcellcenter.lu.se/article/nanostraws-used-deliver-biomolecules-stem-cells - 2025-01-10

Striking research images decorate Lund Biomedical Center

Published 20 August 2020 Sofie Mohlin and Maciej Ciesla with their images, currenlty on display at BMC Lund, level D15. Those who find themselves at Lund BMC can now discover exciting new artwork highlighting the visual side of research. Created by researchers from the Faculty of Medicine, these images were part of ‘The invisible body – art in science’ exhibition held in Stockholm. Here, Christine

https://www.stemcellcenter.lu.se/article/striking-research-images-decorate-lund-biomedical-center - 2025-01-10

New Leadership at Lund Stem Cell Center

Published 1 September 2020 Johan Jakobsson and Johan Flygare. Photo credit: Kennet Ruona Prof. Johan Jakobsson has been appointed as coordinator and Assoc. Prof. Johan Flygare as deputy coordinator of StemTherapy and Lund Stem Cell Center.Together they will continue to manage StemTherapy and Lund Stem Cell Center towards scientific and educational excellence, whilst strengthening the direction of

https://www.stemcellcenter.lu.se/article/new-leadership-lund-stem-cell-center - 2025-01-10

New research paves way for developing therapies that could slow down Alzheimer´s

By Agata [dot] Garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 3 September 2020 Dr. Yuriy Pomeshchik (left) and Dr. Laurent Roybon, lead and senior authors of the study. Photo: Agata Garpenlind Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected

https://www.stemcellcenter.lu.se/article/new-research-paves-way-developing-therapies-could-slow-down-alzheimers - 2025-01-10

Paul Bourgine awarded prestigious European Research Council grant

Published 4 September 2020 Minaturized human bone organs, called “human ossicles”. Image credit: Laboratory for Cell, Tissue and Organ Engineering. Congratulations to Lund Stem Cell Center PI and Wallenberg Fellow Paul Bourgine, who has been awarded European Research Council funding. His research group, the Laboratory for Cell, Tissue and Organ Engineering, are using engineered miniaturized human

https://www.stemcellcenter.lu.se/article/paul-bourgine-awarded-prestigious-european-research-council-grant - 2025-01-10

Researchers to investigate the role of transposable elements in neuroinflammation and Parkinson’s disease

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 16 September 2020 Immunofluorescence image of human neurons derived from stem cells. Image credit: Agnete Kirkeby Prof. Johan Jakobsson and Assoc. Prof. Agnete Kirkeby from Lund Stem Cell Center and University of Copenhagen, along with co-applicants Prof. Roger Barker from Cambridge, UK and Assoc. Prof. Molly Hammell

https://www.stemcellcenter.lu.se/article/researchers-investigate-role-transposable-elements-neuroinflammation-and-parkinsons-disease - 2025-01-10

Successful biotech collaboration brings gene therapy project to the clinic

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 17 September 2020 Histopathology of rescued bone. Femur of an osteopetrotic mouse (left) and rescued bone phenotype in femur following lentiviral mediated gene therapy. Image credit: Johan Richter & Ilana Moscatelli Johan Richter's research has resulted in the successful development of gene therapy for the hereditary d

https://www.stemcellcenter.lu.se/article/successful-biotech-collaboration-brings-gene-therapy-project-clinic - 2025-01-10

Thesis Defence Interview - Nicola Guzzi

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 21 September 2020 Nicola Guzzi defends his PhD thesis Thursday 24th September PhD student Nicola Guzzi will be defending his thesis titled “Post-transcriptional control of stem and cancer cell fate - new roles for an old RNA modification” on Thursday 24th of September 2020. In this interview, Nicola tells us about hi

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-nicola-guzzi - 2025-01-10

Thesis Defence Interview – Marcella Birtele

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 30 September 2020 Marcella Birtele defends her PhD thesis Friday 2nd October Marcella Birtele will be defending her PhD thesis titled “Functional and Transcriptional Studies of Human Dopaminergic Neurons” on Friday 2nd October. Researching within the Developmental and Regenerative Neurobiology group led by Prof. Mali

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-marcella-birtele - 2025-01-10

HUSH and MORC2: new players in transposon regulation during human development

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 15 October 2020 Researcher Christopher Douse. Image credit SSMF. With two articles published in quick succession from his time as a research fellow at Cambridge University, UK, Christopher Douse has moved to Lund Stem Cell Center to develop a research programme on newly-discovered guardians of the human genome. More

https://www.stemcellcenter.lu.se/article/hush-and-morc2-new-players-transposon-regulation-during-human-development - 2025-01-10

Lund Stem Cell Center researcher awarded SSMF Large Grant

By Alexander [dot] Doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 19 October 2020 Immunofluorescence image of reprogrammed astrocytes stained with GFAP (green), actin (red) and Hoechst for the nucleus (blue). Image credit: Isaac Canals Every year the Swedish Society for Medical Research awards funding to promising young medical researchers. Grant recipients are funded for four year

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-researcher-awarded-ssmf-large-grant - 2025-01-10

Novel approach identifies ‘young’ stem cells in old mice

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 20 October 2020 Researcher Els Mansell, first author of the article published in Cell Stem Cell. In a collaborative study, researchers from Lund Stem Cell Center and University College London have developed a novel method of isolating ‘young’ stem cells still present in old mice. They show that activity of mitochondr

https://www.stemcellcenter.lu.se/article/novel-approach-identifies-young-stem-cells-old-mice - 2025-01-10

Lund SCC Image Competition - Time to cast your vote!

By Alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 2 November 2020 Thank you to all who submitted their entries to Lund Stem Cell Center image competition 2020. Now it’s time to choose a winner! Over the past six months, researchers from Lund Stem Cell Center have been submitting images of their research and work environment to the image competition. Now it's time to

https://www.stemcellcenter.lu.se/article/lund-scc-image-competition-time-cast-your-vote-0 - 2025-01-10