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Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes : A nested, case–control study

Produced as a tissue defence response to hypoxia and inflammation, growth differentiation factor-15 (GDF-15) is elevated in people receiving metformin treatment. To gain insight into the relationship of GDF-15 with metformin and major cardiovascular risk factors, we analysed the data from the SUMMIT cohort (n = 1438), a four-centre, nested, case–control study aimed at verifying whether biomarkers

Identifying newborns with umbilical cord blood metabolic acidosis by intrapartum cardiotography combined with fetal ECG ST analysis (STAN) : comparison of the new and old FIGO systems to classify cardiotocograms

Introduction: The intrapartum cardiotocography (CTG) classification system by FIGO in 2015 (FIGO2015) was introduced to simplify CTG interpretation, but it is not harmonized with the fetal ECG ST analysis (STAN) algorithm from 2007 (STAN2007), which is based on the FIGO CTG system from 1987. The study aimed to determine time courses and sensitivity between the systems in classifying CTG + ST event

Clinical and microbiological features of bacteraemia with Gram-positive anaerobic cocci : a population-based retrospective study

Objectives: Gram-positive, anaerobic cocci (GPAC) can cause infections in humans. Only a few cases of bacteraemia with GPAC have been reported. We describe the clinical and microbiological characteristics of GPAC bacteraemia. Methods: A retrospective population-based study of GPAC bacteraemia 2012–2016 in southern Sweden was performed. GPAC were identified using matrix-associated laser desorption

Automated quantification of reference levels in liver and mediastinal blood pool for the Deauville therapy response classification using FDG-PET/CT in Hodgkin and non-Hodgkin lymphomas

Background: 18F-FDG-PET/CT has become a standard for assessing treatment response in patients with lymphoma. A subjective interpretation of the scan based on the Deauville 5-point scale has been widely adopted. However, inter-observer variability due to the subjectivity of the interpretation is a limitation. Our main goal is to develop an objective and automated method for evaluating response. The

Perfusion Monitoring During Oculoplastic Reconstructive Surgery - Opportunities for Optimization of Surgical Techniques

Existing oculoplastic reconstructive surgical techniques are based on empirical knowledge and were established long before perfusion monitoring was possible. It is believed that an avascular graft should always be placed on a vascular bed or flap and also that the viable length of a flap depends on the width of its pedicle. The actual role of the length, width and thickness of a random flap in its

Every-day Life and Energy Use - Self-reported Household Energy Behaviour in Malmö, Sweden

Development in building envelopes and energy efficient systems has an impact in reducing energy use, but the everyday life of the households significantly influences the total performance of the housing sector that in Sweden constitutes 25% of the total energy use. This paper presents and discusses some results of a study investigating the relationship between every-day life and energy use among t

Empowerment and Private Law : Civil Impetus for Sustainable Development

Avhandlingen redovisar en undersökning av samspelet mellan människor i samhällsliv, näringsliv och rättsprocesser, varigenom författaren kartlagt förutsättningarna för enskilda att aktivera civilrättsliga instrument i syfte att främja en utveckling i linje med normer som återspeglas i FNs hållbarhetsmål enligt Agenda 2030.The dissertation is the result of a study of private law viewed as a source This dissertation is the result of a study of private law viewed as a source of power for individuals to enhance values they favour. As an appropriate example of such values, the study has focused on current norms that have been recognized and mirrored as sustainable development goals (SDGs) in the UN Agenda 2030. The research question asks why and under which conditions it is possible for individ

Bootstrap-based bias correction and inference for dynamic panels with fixed effects

In this article, we describe a new command, xtbcfe, that performs the iterative bootstrap-based bias correction for the fixed-effects estimator in dynamic panels proposed by Everaert and Pozzi (2007, Journal of Economic Dynamics and Control 31: 1160–1184). We first simplify the core of their algorithm by using the invariance principle and subsequently extend it to allow for unbalanced and higher o

Harmonizing GIS Education: South - North Perspectives : Lessons learnt from Mozambique, Rwanda, Sweden, and Uganda

The aim of this paper is to critically examine, discuss, draw conclusions, and come up with ideas how to harmonize GIS education in order to realize the envisaged clientele benefits globally. The paper draws experiences and lessons learnt, with examples from ongoing joint GIS MSc programs/courses being implemented in Mozambique, Rwanda, and Uganda. All the five courses (3 in Uganda, 1 in Mozambiqu

XTBCFE: Stata module to perform bootstrap-corrected Fixed Effects estimation and inference in dynamic panel models

xtbcfe is a bootstrap-corrected fixed effects (LSDV) estimator for dynamic panel data models of general order. It estimates the specified model with the fixed effects estimator and corrects its small T bias (see Nickell, 1981) using a simplified but extended version of the approach presented in Everaert and Pozzi (2007). The algorithm evaluates the bias of the fixed effects estimator in a numerica

Bias-Corrected Common Correlated Effects Pooled Estimation In Homogeneous Dynamic Panels

This paper extends the Common Correlated Effects Pooled (CCEP) estimator to homogeneous dynamic panels. In this setting CCEP suffers from a large bias when the time series dimension (T) is fixed. We develop a bias-corrected estimator that is valid for a multi-factor error structure provided that a sufficient number of cross-sectional averages, and lags thereof, are added to the model. We show that

Effect of long-term storage on dietary fibre in different cultivars of carrots

The effect of refrigerated long-term storage (six months) on dietary fibre in raw carrots was investigated in twelve cultivars representing five different groups. In three of the cultivars the viscosity of water-soluble fibre polysaccharides was analysed as well. Further, the bulking capacity of eight cultivars was evaluated through balance experiments in rats. A decrease of certain dietary fibre

Fermentation of dietary fibre in the intestinal tract of rats - a comparison of flours with different extraction rates from six cereals

The fermentation of dietary fibre in wheat, rye, barley, sorghum, rice and maize was investigated in balance experiments with rats. Two different extraction rates, 100% and approximately 65%, were investigated for each cereal grain. In the case of maize, whole maize, and dehulled maize that had been ground and sieved so that it contained mainly endosperm, were investigated. Except for sorghum, die

Binding of 14C-labeled food mutagens (IQ, MeIQ, MeIQx) by dietary fiber in vitro.

Binding of three mutagens, known to occur in fried or broiled foods, by thirteen different types of dietary fiber was investigated in vitro. Nonspecific binding by other food polymers was minimized by using protease and amylase treatment. Water‐insoluble fiber components were responsible for most of the binding capacity. Generally, a slightly larger proportion of 2‐amino‐3,4‐dimethylimidazo [4,5‐f