Filtyp
Background: Standardized definitions of autoimmune disease (AD) are lacking. Therefore, we aim to propose a definition of AD for register-based research and estimate the burden of AD in Sweden as registered in the National Patient Register (NPR) from 1980 to 2023. Methods: Leveraging the NPR, we defined AD as having at least two relevant International Classification of Diseases (ICD) codes represe
The optical response of gold-silver (Au-Ag) alloy nanoparticles is strongly influenced by their localized surface plasmon resonance (LSPR), which can be tuned by varying the particle composition. Accurate simulation of LSPR, often performed using Mie theory, critically depends on the choice of dielectric function, yet available datasets for gold, silver, and their alloys vary widely. In this work,
Distributed multiple-input multiple-output (MIMO), also known as cell-free massive MIMO, emerges as a promising technology for sixth-generation (6G) systems to support uniform coverage and reliable communication. For the design and optimization of such systems, measurement-based investigations of real-world distributed MIMO channels are essential. In this paper, we present a sub-6 GHz indoor chann
The residential sector presents one of the most pressing decarbonisation challenges, especially within historically gas-dependent nations such as the UK. Compounding this challenge, issues of social acceptance have slowed efforts to advance the residential decarbonisation agenda in the UK context. To date, existing technologies such as heat pumps and smart meters, as well as emerging technologies
This article examines how embodied Virtual Reality (VR), when used as a participatory research method, can support the narrative sovereignty of refugees from the Global South by recognising their stories as key sources of knowledge production. This approach challenges dominant humanitarian and state discourses that often frame refugees as passive victims in need of saving. The article critiques th
This review synthesises current evidence on the clinical utility of foam-based posturography in the assessment of vestibular pathologies. It critically evaluates: (1) the physiological mechanisms underlying foam posturography and its capacity to determine vestibular contributions; (2) methodological variability across testing protocols, including differences in foam properties, stance conditions a
Low barriers to trade and access to international capital markets have long been argued to improve economic conditions in a country. However, there is less consensus on the impact of economic globalization on the distribution of those gains across society. There are several possible explanations for the conflicting findings in the existing literature, perhaps most notably endogeneity issues that p
Objective Type I interferons (IFN) drive systemic lupus erythematosus (SLE) pathogenesis. Some patients develop neutralizing IFN autoantibodies (anti-IFN ab), which theoretically could modify disease activity. We aimed to determine the prevalence of anti-IFN ab in patients with SLE, identify the age and when during the disease course of anti-IFN ab emerge, and assess their association with organ d
Background: Postoperative lymph node irradiation can affect shoulder morbidity in breast cancer patients, yet widely accepted dose-volume constraints for the shoulder joint are lacking. The SENOMAC trial randomized patients with breast cancer and 1–2 sentinel lymph node (SLN) macrometastases to axillary lymph node dissection (ALND) or SLN biopsy only. We aimed to analyze the association between th
Finding the optimal subset of individuals to observe in order to obtain the best estimate of the average opinion of a society is a crucial problem in a wide range of applications, including policy-making, strategic business decisions, and the analysis of sociological trends. We consider the opinion vector X to be updated according to a DeGroot opinion dynamical model with stubborn agents, subject
Bacteriophages must overcome diverse bacterial immune systems, yet the molecular principles enabling such escape remain poorly understood. Here, we show that the phage homing endonuclease SegB facilitates immune evasion by promoting the segmental amplification of anti-defense loci. The antiphage defense Septu inhibits phage T6 replication by cleaving the variable loop of tRNATyr. We show that SegB
Rapid warming in the Arctic is transforming northern ecosystems and altering their role in the global carbon cycle. Rising temperatures are driving shifts in vegetation composition, phenology, and ecosystem functioning, including earlier growing seasons and the expansion of shrubs across tundra landscapes. These changes influence surface energy balance, carbon uptake, and climate feedbacks, yet su
In 2024, the European Academy of Paediatrics (EAP) published a list of 10 low-value practices in paediatric care. Embedded in the Choosing Wisely framework, this list is a step towards promoting targeted and evidence-based care. However, no single recommendation can change prescription habits and we need to acknowledge that overuse of the available resources has multiple causes. Among them, the ph
Sammanfattning Kapitel 2 Presentation av ett nytt tumör-behandlingskoncept med ”Pre-kirurgisk intermittent ultrahypofraktionerad strålbehandling” (PSiRT) ”kombinerad med immunterapi” (PSiRIT), särskilt immun¬kontrollpunktshämmare (anti-CTLA4 och anti-PD-1).Intermittent ultrahypofraktionerad strålbehandling innebär:• Optimal absorberad dos 6–8 Gy per fraktion • Doser >10 Gy kan öka immunosuppress
This chapter highlights the centrality of atmospheres in tightly controlled environments like courtrooms and youth detention homes. In courtrooms, social control is achieved through affective arrangements, such as reading emotional cues and using touch or its avoidance to manage order. Legal professionals rely on their ability to sense and act on shifting atmospheres as part of their implicit skil
Critical events frequently occur in hospital settings. Cinematic portrayals of medicine and medical environments can illuminate historical developments and perspectives on healthcare, medical professions, and specialisations. This article aimed to explore the interplay between structural framework, professional, and relational factors when facing critical events and their management in a hospital
