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Asymmetric cross rolling : A new technique for alleviating orientation-dependent microstructure inhomogeneity in tantalum sheets

New rolling technique, i.e. asymmetric rolling combined with cross rolling is adopted to produce Ta sputtering targets in this study. Electron backscatter diffraction (EBSD) analysis suggests that (111) and (100) deformed grains distribute alternately along normal direction in cross rolling (CR) and asymmetric cross rolling (ACR) samples. Misorientation angle distribution indicates that severe ori

Microscopic colitis and its associations with complications observed in classic inflammatory bowel disease : a systematic review

Objectives: Crohn’s disease and ulcerative colitis are associated with an increased risk to develop anemia, cutaneous diseases, liver diseases, malignancy, osteoporosis, rheumatic diseases, thromboembolism and uveitis. The association between these diseases and microscopic colitis (MC) is not known. The aim of the present systematic review was to examine associations between MC and diseases observ

A Phase 2a Trial Investigating the Safety and Tolerability of the Novel Cortical Enhancer IRL752 in Parkinson's Disease Dementia

Background: IRL752 is a novel small-molecule compound that acts to regioselectively enhance norepinephrine, dopamine, and acetylcholine neurotransmission in the cerebral cortex. Objective: The primary objective of the trial was to investigate the safety and tolerability of IRL752 in patients with Parkinson's disease and dementia. Methods: Patients with Parkinson's disease and dementia were randomi

Excitation wavelength dependence of photoluminescence flickering in degraded MAPbI3 perovskite and its connection to lead iodide formation

Metal halide perovskite semiconductors often exhibit photoluminescence blinking and flickering when luminescence of individual small nano- or even microcrystals is monitored. The nature of these fluctuations is not well understood but must be related to the presence of metastable non-radiative recombination channels and efficient charge migration in these materials. Here we report on the excitatio

Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course - A joint PhD student course at University College London and University of Gothenburg

Until relatively recently, a diagnosis of probable Alzheimer's disease (AD) and other neurodegenerative disorders was principally based on clinical presentation, with post-mortem examination remaining a gold standard for disease confirmation. This is in sharp contrast to other areas of medicine, where fluid biomarkers, such as troponin levels in myocardial infarction, form an integral part of the

Measurement of Azimuthal Anisotropy of Muons from Charm and Bottom Hadrons in pp Collisions at s =13 TeV with the ATLAS Detector

The elliptic flow of muons from the decay of charm and bottom hadrons is measured in pp collisions at √s=13 TeV using a data sample with an integrated luminosity of 150 pb-1 recorded by the ATLAS detector at the LHC. The muons from heavy-flavor decay are separated from light-hadron decay muons using momentum imbalance between the tracking and muon spectrometers. The heavy-flavor decay muons are fu

Male unaccompanied refugee minors’ perceptions of relationships and information about sexual health in Sweden - ‘it feels like you’ve been in prison and then set free’

Unaccompanied refugee minors represent a potentially vulnerable group regarding sexual and reproductive health and rights, particularly due to the circumstances surrounding their migration. Research is scarce about the sexual and reproductive health and rights needs of unaccompanied minors, many of whom come from countries with limited access to information about sexual and reproductive health and

IEEE Std. P1687.1 for Access Control of Reconfigurable Scan Networks

We address access control of reconfigurable scan networks, like IEEE Std. 1687 networks. We propose an on- chip test block to perform: (1) test for faulty scan-chains, (2) localization of faulty scan-chains and (3) repair by excluding faulty scan-chains, and an access control block to (1) control so scan- chains (instruments) are only accessed in allowed combinations, (2) detection of access attem

Secondary Fracture Prevention : Consensus Clinical Recommendations from a Multistakeholder Coalition

Osteoporosis-related fractures are undertreated, due in part to misinformation about recommended approaches to patient care and discrepancies among treatment guidelines. To help bridge this gap and improve patient outcomes, the American Society for Bone and Mineral Research assembled a multistakeholder coalition to develop clinical recommendations for the optimal prevention of secondary fractuream

An integrative phenotype–genotype approach using phenotypic characteristics from the UAE national diabetes study identifies HSD17B12 as a candidate gene for obesity and type 2 diabetes

The United Arab Emirates National Diabetes and Lifestyle Study (UAEDIAB) has identified obesity, hypertension, obstructive sleep apnea, and dyslipidemia as common phenotypic characteristics correlated with diabetes mellitus status. As these phenotypes are usually linked with genetic variants, we hypothesized that these phenotypes share single nucleotide polymorphism (SNP)-clusters that can be used

Global Stroke Statistics 2019

Background: Data on stroke epidemiology and availability of hospital-based stroke services around the world are important for guiding policy decisions and healthcare planning. Aims: To provide the most current incidence, mortality and case–fatality data on stroke and describe current availability of stroke units around the world by country. Methods: We searched multiple databases (based on our exi

Adverse Pregnancy Outcomes after Multi-Professional Follow-Up of Women with Systemic Lupus Erythematosus : An Observational Study from a Single Centre in Sweden

While the management of pregnant patients with systemic lupus erythematosus (SLE) has improved over the last decades, the risk of maternal, foetal, and neonatal complications is still substantial. We evaluated the occurrence of adverse pregnancy outcomes (APO) occurring in 2002-2018 among patients with SLE from the catchment area of the Department of Rheumatology in Lund, Sweden. Longitudinal clin

Towards better lighting recommendations for open surgery

This study assesses the lighting requirements for operating theatres and the lighting conditions in a specific test case and proposes alternate ways of achieving a favourable visual environment. The hypothesis was that an increased illuminance level from general lighting and lower luminance contrasts between the essential task areas affect perceived lighting quality, visual ability and performance

Fundamental Bounds for Volumetric Structures and Their Feasibility

Fundamental bounds on antenna and scattering metrics are presented in this paper utilizing volumetric method of moments. This makes it possible to investigate scenarios not solvable with classical surface method of moments which assumes that good conductors as used. One practical example is the study of plasmonic devices whose operation relies on the interaction between material properties and rad