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Analysis of particle size distribution changes between three measurement sites in Northern Scandinavia

Measured aerosol size distributions from three measurement stations and modeled air mass trajectory data were combined to study aerosol dynamics in the boreal forest zone in Northern Scandinavia. Three approaches were used: investigation of new particle formation events, analysis of air masses arriving from ocean to continent, and study of changes in the aerosol size distributions when air masses

A somatic mutation in moesin drives progression into acute myeloid leukemia

Acute myeloid leukemia (AML) arises when leukemia-initiating cells, defined by a primary genetic lesion, acquire subsequent molecular changes whose cumulative effects bypass tumor suppression. The changes that underlie AML pathogenesis not only provide insights into the biology of transformation but also reveal novel therapeutic opportunities. However, backtracking these events in transformed huma

Renewable energy transition, demand for metals and resource curse effects

Mitigating climate change will require large-scale changes to energy systems. Two examples are increased use of renewable energy resources and electrification of the transport sector. These changes increase demand for metals. This chapter looks into which metals are used in renewable energy technologies and why, how much is required to transition the global energy system and which countries hold t

Women´s experiences of preeclampsia as a condition of uncertainty : a qualitative study

BACKGROUND: Preeclampsia is a severe condition that annually affects about 3-8% of pregnancies worldwide. Preeclampsia is thereby one of the most common pregnancy complications for both mother and child. Despite that, there is limited research exploring the women´s perspective of experiencing preeclampsia.AIM: The aim of this study was to describe women´s experiences of preeclampsia to improve the

A Brake System Coefficient of Friction Estimation Using 3D Friction Maps

The coefficient of friction (COF) is one of the core factors in the evaluation of brake system performance. It is challenging to predict the COF, since it is strongly influenced by several parameters such as contact pressure (p), slip rate (v) and temperature (T) that depend on the driving conditions. There is a need for better models to describe how the brake friction varies under different drivi

Selection of Weather Files and Their Importance for Building Performance Simulations in the Light of Climate Change and Urban Heat Islands

Building performance predictions and their reliability rely heavily on weather data inputs. Climate is affected by spatial and temporal differences related to climate change and urban heat island effects, but the weather files used in building performance simulations (BPS) often remain unchanged and may represent weather observations generated from inadequate space and time for their application.

Degrowth & Strategy : How to bring about social-ecological transformation

Degrowth is a counter-hegemonic movement that has the ambitious aim of transforming society towards social and ecological justice. But how do we get there? That is the question this book addresses. Adhering to the multiplicity of degrowth whilst also arguing that strategic prioritisation and coordination are key, Degrowth & Strategy advances the debate on strategy for social-ecological transfo

Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells

Sjögren's disease is a complex autoimmune disease with twelve established susceptibility loci. This genome-wide association study (GWAS) identifies ten novel genome-wide significant (GWS) regions in Sjögren's cases of European ancestry: CD247, NAB1, PTTG1-MIR146A, PRDM1-ATG5, TNFAIP3, XKR6, MAPT-CRHR1, RPTOR-CHMP6-BAIAP6, TYK2, SYNGR1. Polygenic risk scores yield predictability (AUROC = 0.71) and

Transformative innovation policy : A novel approach?

The focus and instruments of innovation policy have changed fundamentally over the last decades. Recently transformative innovative policy has caught the attention of scholars and policymakers, who argue that this is a new shift in the policy discourse. Even though grand challenges such as global warming and migration flows, as well as technological change such as artificial intelligence and indus

An Experimental Investigation of Directly Injected E85 Fuel in a Heavy-Duty Compression Ignition Engine

A commercially available fuel, E85, a blend of ~85% ethanol and ~15% gasoline, can be a viable substitute for fossil fuels in internal combustion engines in order to achieve a reduction of the greenhouse gas (GHG) emissions. Ethanol is traditionally made of biomass, which makes it a part of the food-feed-fuel competition. New processes that reuse waste products from other industries have recently

Application of Machine Learning and Remote Sensing in Hydrology

Water is vital to all life on earth, but its management is becoming more difficult owing to the behavior of water in nature such as water dynamics, water movements, and different forms of water in nature. In addition, population growth, the impact of climate change, and the inappropriate use of water resources add more complexity to water resource management. The integration of natural sciences ne