Neural stem and progenitor cells hold the promise to be used in cell-based therapies to treat both acute and degenerative neurological diseases. To date, most research has been focused on the use of in vitro propagated stem cells used as a source of cells in cell replacement therapies. However, mobilization of endogenous neural stem cells to generate a specific differentiated cell type offers an a

We consider the problem of determining for each pair of vertices of a directed acyclic graph (dag) on n vertices whether or not it has a unique lowest common ancestor, and if so, finding such an ancestor. We show that this problem can be solved in time O(n ω logn), where ω< 2.376 is the exponent of the fastest known algorithm for multiplication of two n×n matrices. We show also that the problem of

Antisense oligodeoxynucleotides to endothelin ETA receptor mRNA were used to characterize vascular smooth muscle receptors. The concentration-response curve showed a significant attenuation of endothelin-1-induced contraction in circular segments of the human superficial temporal artery. Endothelin ETB receptor antisense or mismatch oligodeoxynucleotides showed no alteration of the endothelin-1-in

This study investigated to what extent, and under what circumstances, pair collaboration influences the realism in eyewitness confidence in event memory. The participants first saw a short film clip and then confidence rated their answers to questions on its content. A condition (the Individual-Pair condition) where individual effort preceded pair collaboration showed better calibration compared w

Background: Nocturnal ventilatory support by nasal positive pressure ventilation (NPPV) is an established treatment method in patients with chronic alveolar hypoventilation (CAH). The knowledge about its long-term effects on health-related quality of life (HRQL) is limited. Methods: In a prospective, longitudinal, single-strand study, patients with CAH caused by non-COPD conditions, consecutively

This article examines differences in health among immigrants in Sweden from 1990 to 2001. Controlling for demographic characteristics, most immigrant groups display higher rates of hospitalisation than native Swedes, but when socio-economic factors are introduced, only Nordic immigrants display rates that are significantly higher than for Swedish-born individuals. High rates of hospitalisation amo

Different screening models in quantum cascade lasers are compared by calculating the contribution of intrasubband impurity scattering to the optical linewidth as a function of temperature. We find a strong impact of impurity scattering, which increases substantially with temperature. A simple isotropic bulk screening model works well if the screening length is of the order of or longer than the pe

Background: The incidence of arm lymphoedema after treatment for breast cancer ranges from 1 to 49 percent. Although most women can be treated by non-operative means with satisfying results, end-stage lymphoedema is often non-responsive to compression, where hypertrophy of adipose tissue limits the outcome value of compression or massage. Methods: This was a prospective study of 37 women with unil

Dawkins in his The Selfish Gene(1) quite aptly applies the term "selfish" to parasitic repetitive DNA sequences endemic to eukaryotic genomes, especially vertebrates. Doolittle and Sapienza (2) as well as Orgel and Crick (3) enlivened this notion of selfish DNA with the identification of such repetitive sequences as remnants of mobile elements such as transposons. In addition, Orgel and Crick (3)

Metasedimentary granulites from the central portion of the Belarus-Podlyasie granulite belt were studied with the purpose to reproduce the Paleoproterozoic tectono-thermal evolution in the western part of the East European craton. The regularities identified in the compositional variations in minerals (particularly, garnet), textural relations between minerals, and thermobarometric data point to t

A series of CCK2 receptor ligands were analysed with respect to their interaction with binding sites in the membranes of COS-7 cells and SK-N-MC cells transiently expressing the human CCK2 receptor (short isoform). The ligands were YF476, YM022, AG041R, L-740,093, JB93182, PD134308, and PD136450. Their binding was analysed by radioligand competition using [H-3]L-365,260 as the labelled ligand. Sat

The lidar technique is an efficient tool for remote monitoring of the distribution of a number of atmospheric species. We study measurements of sulphur dioxide emitted from the Italian volcano Mt. Etna. This study is focused on the treatment of data and on the procedure to evaluate range-resolved concentrations. In order to make an in-depth analysis, the lidar system was prepared to store measurem

The phase behavior and phase structure of the mixed lecithin/DDAB system in water are studied by SAXS, H-2 NMR, cryo-TEM, and optical polarization microscopy methods. Macroscopically, the triangular phase diagram is dominated by one lamellar liquid crystalline region. SAXS data in combination with 2H NMR detect the presence of two different lamellar phases. The collapsed lamellar phase originated

Protein C inhibitor (PCI) is a serine protease inhibitor, displaying broad protease specificity, found in blood and other tissues. In blood, it is capable of inhibiting both procoagulant and anticoagulant proteases. Mechanisms that provide specificity to PCI remain largely unrevealed. In this study we have for the first time provided a full explanation for the marked size heterogeneity of blood-de

To define fibre type grouping in terms of random and non-random arrangements of the two fibre types, type 1 (ST) and type 2 (FT), we adopted the measure of counting the number of "enclosed fibres". The statistical properties of the number of enclosed fibres, and the number and size of groups of enclosed fibres were studied in computer-simulated muscle cross-sections, using a model based upon hexag

Development of kindling and mossy fiber sprouting, and changes of gene expression were studied after 40 seizures produced during about 3 h by electrical stimulation every 5 min in the ventral hippocampus. As assessed by 5 test stimulations, enhanced responsiveness was present already after 6-24 h but from 1 week post-seizure increased gradually up to 4 weeks without additional stimuli. Sprouting o