Context: Digitalization brings new opportunities and also challenges to software companies.Objective: Software companies have mostly focused on the technical aspects of handing changes and mostly ignoring the business model changes and their implications on software organization and the architecture. In this paper, we synthesize implications of the digitalization based on an extensive literature s

In market-driven product development, it is important that the software product is released to the market at the right time, and offers higher quality than the competitors. In release planning, the allocation of development effort in investments into product enhancements, functions are competing with quality requirements for limited resources. In addition, it is important to find the right balance

We perform an explorative analysis of employment patterns in the foundationaleconomy producing mundane everyday necessities and providing welfare services across Swedish regional labour markets between 2007 and 2016. We focus specifically on hierarchical patterns in spatial distribution of foundational activities and their association – direct and through integration with other economic activities

Background: The goal of postnatal care is to provide the highest possible quality of care and medical safety with the least possible intervention in order to optimize health and wellbeing of the new family. The aim of the study was to describe mothers´ experiences in relation to a new postnatal home-based model of midwifery care. Methods: The current study uses a cross-sectional mixed method desig

BACKGROUND: Insulin resistance (IR) in skeletal muscle is a key feature of the pre-diabetic state, hypertension, dyslipidemia, cardiovascular diseases and also predicts type 2 diabetes. However, the underlying molecular mechanisms are still poorly understood.METHODS: To explore these mechanisms, we related global skeletal muscle gene expression profiling of 38 non-diabetic men to a surrogate measu

The Azerbaijan-Armenia war on Nagorno-Karabakh was a serious challenge for the foreign policy of the Islamic Republic in Iran.

The development of social media challenges the established conceptualizations of resources in social movements. While previous theories largely illustrated social movements as constantly searching for new and more resources, the development of social media has allowed some actors to gather and mobilize extensive resources rapidly, calling for an analysis of resource abundance. The aim of this artiThe development of social media challenges the established conceptualizations of resources in social movements. While previous theories largely illustrated social movements as constantly searching for new and more resources, the development of social media has allowed some actors to gather and mobilize extensive resources rapidly, calling for an analysis of resource abundance. The aim of this arti

The interaction of simultaneous fracture and buckling constitutes problems at manufacturing and handling of thin foils. Buckling occurs as an additional event that complicates the prediction of the critical load that may lead to fracture. For most sufficiently thin foils the plastic slip occurs through the foil thickness which leads to reduction of the cross section width until the foil fails. The

Abstract: We present a small angle X-ray scattering (SAXS) study of the colloidal structure of regenerated cellulose fibers, air-gap spun from an ionic liquid solution. Based on the data, and a different interpretation of the anisotropic SAXS pattern, we propose a slightly different colloidal structure of the fibers, than what is commonly assumed for regenerated cellulose fibers. Fibers with two d

The transport sector needs to become sustainable and public transport has an important role to play. Green public procurement has proven to have great potential to influence the transition to a sustainable public transport sector. Sweden is a good example of a country that uses public procurement in the public transport sector to a large extent and has at the same time come far in the transition t

Monolithic integration of III-V semiconductors with Silicon technology has instigated a wide range of new possibilities in the semiconductor industry, such as combination of digital circuits with optical sensing and high-frequency communication. A promising CMOS compatible integration process is rapid melt growth (RMG) that can yield high quality single crystalline material at low cost. This paper

Background: Studies carried out in simulated environments suggest that checklists improve the management of surgical and intensive care crises. Whether checklists improve the management of medical crises simulated in actual emergency departments (EDs) is unknown. Methods: Eight crises (anaphylactic shock, life-threatening asthma exacerbation, haemorrhagic shock from upper gastrointestinal bleeding

Recognition of impact-induced deformation of minerals is crucial for the identification and confirmation of impact structures as well as for the understanding of shock wave behavior and crater formation. Shock deformed mineral grains from impact structures can also serve as important geochronometers, precisely dating the impact event. We investigated zircon grains from the Mien impact structure in

Gender biases have been documented in many areas including hiring, promotion, or performance evaluations. Many of these decisions are made by committees. We experimentally investigate whether committee deliberation contributes to gender biases. In our experiments, participants perform a real effort task and then rate the task performance of other participants. Across treatments we vary the extent

Gene amplification is considered to be one responsible cause for upregulation of Programmed Death Ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) and to represent a specific molecular subgroup possibly associated with immunotherapy response. Our aim was to analyze the frequency of PD-L1 amplification, its relation to PD-L1 mRNA and protein expression, and to characterize the immune microenv