Popular Abstract in Swedish Det är en utmaning att behandla patienter med allvarliga infektioner eftersom immunförsvaret reagerar olika på olika mikroorganismer. Immunförsvarets reaktion har i sin tur en stor betydelse för symtombild, kliniska fynd och prognos. Vid blodförgiftning (sepsis) förändras dessutom sannolikt immunsvaret under det kliniska förloppet. Man tror att det inledningsvis vid sepInfectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. There is often a rapid onset, which may constitute a diagnostic and therapeutic challenge, whereas in other cases an extensive investigation over a long time period can fail to ident

Previous research on victimhood during and after the Bosnian war has emphasized the importance of narratives but has not focused on narratives about victimhood or analyzed post-war interviews as a competition for victimhood. This article tries to fill this gap using stories told by survivors of the Bosnian war during the 1990s. In this analysis of the retold experiences of 27 survivors of the war

Virtual meetings (VMs), i.e. audio-, video- and web-conferencing, could be used to decrease the environmental impact of business activities, reduce travel costs, increase business mobility and collaboration, and improve flexibility and productivity of the employees. Swedish national policy supports the implementation of VMs as one of the solutions towards low carbon infrastructure and sustainable

The association between hydrophobically modified polyethylene glycol, HM-PEG, and non-ionic vesicles of tetraethylene glycol monododecyl ether, C12E4, was investigated. HM-PEG is in a triblock form, with an alkyl chain attached to each hydrophilic polymer-end. Such polymer structure is denoted as telechelic. The vesicle average radius was measured by self-diffusion measurements. The system exhibit

Objective: To describe dietary carbohydrate intakes and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Between 1995 and 2000, 36 034 subjects, aged between 35-74 years, were administered a standardized, 24-h dietary recall using a computerized interview software programme (EPIC-SOFT). Inta

The mechanisms of neuronal cell death are still only poorly understood, which has hindered the advancement of therapies for many currently untreatable neurodegenerative diseases. This calls for the development of new methods which reveal critical molecular mechanisms of the celldeath machinery with both high sensitivity and cellular resolution. Using animal models for hereditary neurodegeneration

Three hot break tomato pastes were investigated to determine the effect of their characteristics on the properties of tomato ketchup, processed in an industrial-scale facility (i.e. diluted, heated, homogenized and cooled). Pastes and ketchups were characterized by particle size distribution, volume fraction, and rheological behavior in steady and dynamic shear. The ketchups were also subjected to

The aim of the study was to assess the short-term cardiorespiratory effects of a standard red cell transfusion in very low birth weight (

Reduction of cellular polyamine pools results in inhibition of cell proliferation and sometimes in induction of cell death. Reduction of cellular polyamine pools can be achieved by several strategies involving all the mechanisms of polyamine homoeostasis, i.e. biosynthesis, catabolism and transport across the cell membrane. In the present paper, we concentrate on results achieved using the polyami

I Doktorandbarometern 2007 har över 700 doktorander vid Lunds universitet bidragit med sina erfarenheter av forskarutbildningen. En väsentlig del av dessa erfarenheter var gemensamma, trots att de representerade olika vetenskapsområden. Ett annat intressant resultat visade på betydelsen av doktoranders delaktighet och medarbetarskap i forskarutbildningsmiljön. De som huvudsakligen arbetade inom ra

Background and Purpose-Secondary prevention is recommended after stroke, but adherence to guidelines is unknown. We studied the prescription of antiplatelet drugs, angiotensin-converting enzyme inhibitors, statins, and anticoagulant drugs and their relation to risk of death. Methods-Patients with first-ever ischemic stroke in 2005 were registered in the Swedish Stroke Register. Odds ratios, hazard

Cardiac rhabdonnyomas are rare and often regress spontaneously. However, the management of rhabdomyoma with severe inflow and outflow obstructions is a challenge. An infant with a massive left ventricular rhabdomyoma mimicking the haemodynamics of hypoplastic left heart syndrome is reported. Surgery could not be contemplated because the mitral valve leaflets and chordae were imbedded in the tumour

Översatt utdrag ur introduktionskapitlet till boken Mary Wollstonecraft and Feminist Republicanism.

Objective. The authors aimed to investigate the incidence and outcomes of acute upper gastrointestinal bleeding (AUGIB) and to examine the role of drugs potentially associated with AUGIB. Methods. The study was prospective, population-based and consisted of all patients who underwent upper gastrointestinal endoscopy (UGE), during the year of 2010 at the National University Hospital of Iceland. Dru

Studies in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, have shown that B cells markedly influence the course of the disease, although whether their effects are protective or pathological is a matter of debate. EndoS hydrolysis of the IgG glycan has profound effects on IgG effector functions, such as complement activation and Fc receptor binding, suggesting

Background: Although widely used, the validity and reliability of the Clavien classification of postoperative complications have not been tested in urologic procedures, such as percutaneous nephrolithotomy (PCNL). Objective: To validate the Clavien score and categorise complications of PCNL. Design, setting, and participants: Data for 528 patients with complications after PCNL were used to create

The aim of this paper is to study rate-dependent switching in ferroelastic materials. More specifically, a micro-mechanically motivated model is embedded into an iterative three-dimensional and electromechanically coupled finite element framework. An established energy-based criterion serves for the initiation of domain switching processes as based on reduction in (local) Gibbs free energy. Subseq

Measurements of the midrapidity transverse-energy distribution, dE(T)/d eta, are presented for p + p, d+Au, and Au+Au collisions atv root s(NN) = 200 GeV and additionally for Au+Au collisions atv root s(NN) = 62.4 and 130 GeV. The dE(T)/d eta distributions are first compared with the number of nucleon participants N-part, number of binary collisions N-coll, and number of constituent-quark particip

Using survey data from a large public research organization, this study examines entrepreneurship propensities of academic researchers, focusing on gender differences. Although sample means of female and male propensities toward entrepreneurship are fairly similar, regression estimates show significant gender differences in the association of several factors with propensities to start businesses.