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The Conditions of Complex Innovation Adoption Occurrence — A Critical Realist Perspective

Abstract: The adoption of innovation is a multifaceted and dynamic phenomenon. It occurs as a result of the interplay between structural influences and agents’ activities. Although existing studies on innovation have recognised the importance of theories that link the structure, the macro level, and agency, the micro level, in explaining changes over time, few theoretical accounts support the inte

In-silico modeling of atrial repolarization in normal and atrial fibrillation remodeled state

Atrial fibrillation (AF) is the most common cardiac arrhythmia, and the total number of AF patients is constantly increasing. The mechanisms leading to and sustaining AF are not completely understood yet. Heterogeneities in atrial electrophysiology seem to play an important role in this context. Although some heterogeneities have been used in in-silico human atrial modeling studies, they have not

Apparent heterogeneity in the pIII-peptide fusion protein in single-phage clones isolated from peptide libraries

Ligand homogeneity is an important issue in affinity chromatography. Using phages expressing peptides on the pIII protein, a heterogeneity in the binding of monoclonal phages was observed during affinity chromatography on supermacroporous cryogels. Fractions with different apparent binding affinities could be separated by stepwise elution. When these different fractions were re-applied, the respec

Antioxidant airway responses following experimental exposure to wood smoke in man

Background: Biomass combustion contributes to the production of ambient particulate matter (PM) in rural environments as well as urban settings, but relatively little is known about the health effects of these emissions. The aim of this study was therefore to characterize airway responses in humans exposed to wood smoke PM under controlled conditions. Nineteen healthy volunteers were exposed to bo

Projectification in Swedish municipalities. A case of porous organizations

This article aims to expand our understanding of projectification in Swedish municipalities. Above all the article explores to what extent processes of projectification can be identified and if so how they unfold. The article draws its inspiration from critical management studies and uses the notion of sensemaking to identify the practices of projectification processes. Three processes of projecti

Liquid ionization chamber calibrated gel dosimetry in conformal stereotactic radiotherapy of brain lesions

Hypofractionated conformal stereotactic radiotherapy (HCSRT) is an established method of treating brain lesions such as arteriovenous malformations (AVMs) and brain metastases. The aim of this study was to investigate the reliability of treatment plans in the terms of dose distribution and absorbed dose for HCSRT. Methods and materials. Treatment plans for three different clinical intracerebral ta

Child Sexual Abuse: Community Concerns in Urban Tanzania

The aim of this study was to explore community perceptions about child sexual abuse in Tanzania. Thirteen focus group discussions were conducted with adult community members. The core category, children's rights challenged by lack of agency, was supported by eight categories. Aware but distressed portrayed feelings of hopelessness, lack of trust in the healthcare and legal systems reflected percei

Differential HIF-1α and HIF-2α Expression in Mammary Epithelial Cells during Fat Pad Invasion, Lactation, and Involution.

The development and functional cycle of the mammary gland involves a number of processes that are caricatured by breast cancer cells during invasion and metastasis. Expression of the hypoxia-inducible transcription factors HIF-1 and HIF-2 has been associated with metastatic, poor prognosis, and high-grade breast cancers. Since hypoxia affects normal epithelial differentiation, we hypothesise that

Autumn migratory fuelling: a response to simulated magnetic displacements in juvenile wheatears, Oenanthe oenanthe

Recent experiments exposing migratory birds to altered magnetic fields simulating geographical displacements have shown that the geomagnetic field acts as an external cue affecting migratory fuelling behaviour. This is the first study investigating fuel deposition in relation to geomagnetic cues in long-distance migrants using the western passage of the Mediterranean region. Juvenile wheatears (Oe

Neutron capture imaging of 10B in tissue specimens

Boron Neutron Capture Therapy (BNCT) is an attractive concept for radiation treatment of malignant tumours. The patients receive a 10B-carrying compound with selective uptake in tumour cells, after which they are irradiated with epithermal neutrons. Theoretically, the tumour cells are killed by the high-LET particles produces in 10B(n, alpha)7Li reactions inside or close to the cell nucleus, while

On variation in Faroese verb placement

In this paper, we present and discuss results from an investigation of verb placement in modern Faroese in which we collected data from speakers from a number of different dialect areas in the Faroe Islands. Altogether we interviewed 54 informants (age 15 – 67, 29 women and 25 men). Therefore, our study not only investigates the geographical variation claimed to be present in Faroese with respect

Välfärdsbilder : svensk film utanför biografen

Abstract in Undetermined In this anthology, twenty-three scholars from seven academic disciplines analyze film in Sweden never distributed to the cinema. Encompassing more than a centurys, the book gives a broad overview of the role of moving images in relation to the the Swedish model welfare state. The material includes amateur film, education film, industrial film and avant-garde film. The book

Twisted Amide Analogues of Tröger's Base.

Let's do the twist: The first twisted bis-amide is obtained by the benzylic oxidation of Tröger's base (TB). Kinetic studies of its acidic hydrolysis reveal that the hydrolysis is to a large extent funneled through doubly protonated species.

Sionismen i kris

Recension av Ingmar Karlsson: Bruden är vacker men har redan en man. Sionismen – en ideologi vid vägs ände & Peter Beinart: Zionism in Crisis

Treatment for retinopathy of prematurity in infants born before 27 weeks of gestation in Sweden

Aims To study various aspects of treatment for retinopathy of prematurity (ROP) in a Swedish population of extremely preterm infants born before 27 weeks of gestation. Methods A national, prospective and population-based study was performed in Sweden from 1 April 2004 to 31 March 2007. The criteria for the treatment of ROP accorded with the recommendations of the Early Treatment for Retinopathy of

Exposure to tetrachloroethylene in dry cleaning shops in the Nordic countries

Objectives: Tetrachloroethylene is the dominant solvent used in dry cleaning worldwide and many workers are potentially exposed. We report here on results of 1296 measurements of tetrachloroethylene undertaken in Nordic dry cleaning shops 1947–2001. Methods: We searched documents and files in the Nordic institutes of occupational health for air measurements of tetrachloroethylene. Repeated measur