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Aerosol indirect effects on continental low-level clouds over Sweden and Finland

Aerosol effects on low-level clouds over the Nordic Countries are investigated by combining in situ ground-based aerosol measurements with remote sensing data of clouds and precipitation. Ten years of number size distribution data from two aerosol measurement stations (Vavihill, Sweden and Hyytiälä, Finland) provide aerosol number concentrations in the atmospheric boundary layer. This is combined

Effects of cyclin D-1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study

Introduction: Gene amplification of CCND1 is observed in a subgroup of breast cancers with poor prognosis, whereas overexpression of the protein cyclin D-1 has been linked to both worse and better clinical outcome. CCND1 amplification and protein overexpression have also been associated with resistance to treatment with tamoxifen or even to a potentially detrimental effect of tamoxifen. Methods: T

Manganese and selenium concentrations in umbilical cord serum and attention deficit hyperactivity disorder in childhood.

Existing evidence on the effects of manganese and selenium during fetal life on neurodevelopmental disorders is inadequate. This study aims to investigate the hypothesized relationship between fetal exposure to manganese and selenium and attention deficit hyperactivity disorder (ADHD) diagnosis in childhood. Children born between 1978 and 2000 with ADHD (n=166) were identified at the Department of

Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats

Aims/hypothesis High plasma copeptin, a marker of vasopressin (VP) secretion, has been shown to be associated with the metabolic syndrome and development of type 2 diabetes in humans. The present study was designed to determine the long-term influence of plasma VP concentration in a rodent model prone to metabolic dysfunction. Methods Obese Zucker rats and their lean counterparts were submitted fo

Recommendation to include methylisothiazolinone in the European baseline patch test series - on behalf of the European Society of Contact Dermatitis and the European Environmental and Contact Dermatitis Research Group.

Methylisothiazolinone (MI) is used as a preservative in occupational and household products, and cosmetics. It is a part of the preparation of methylchloroisothiazolinone (MCI)/MI, which is patch tested in water in the European baseline series. However, this preparation fails to detect a significant percentage of allergic contact reactions to MI.

An occupational therapy approach to the support of a young immigrant female's mental health: A story of bicultural personal growth.

Young immigrants who suffer from psychosis perceive their illness from the outlook of at least two cultures, which is often a source of confusion and misunderstanding for clients, their families, and clinicians. This article presents a case study with a narrative approach, aiming to illustrate how an occupational therapy intervention can highlight the role of culture and address bicultural identif

Enhanced low-template DNA analysis conditions and investigation of allele dropout patterns.

Forensic DNA analysis applying PCR enables profiling of minute biological samples. Enhanced analysis conditions can be applied to further push the limit of detection, coming with the risk of visualising artefacts and allele imbalances. We have evaluated the consecutive increase of PCR cycles from 30 to 35 to investigate the limitations of low-template (LT) DNA analysis, applying the short tandem r

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Abstract in Romanian ntemeiată la 1348, Universitatea Carolină din Praga se numără printre cele mai vechi instituţii de învăţământ superior din lume. Studiul limbii române beneficiază aici de o bogată tradiţie, acesta fiind introdus la catedra de limbi romanice a Universităţii încă din anul 1882 de către profesorul ceh de filologie Jan Urban Jarník (1848-1923). Este notabil şi faptul că UniversitaFounded in 1348, Charles University in Prague is among the oldest academic institutions in the world. Teaching the Romanian language has a longstanding tradition as well: it was established by the Czech philologist Jan Urban Jarník (1848-1923) within the Romance Department in 1882. Thus Charles University in Prague became the fifth university outside Romania that began teaching Romanian language (

Economic optimization design of shell-and-tube heat exchangers by a cuckoo-search-algorithm

This paper presents an optimization of shell and tube heat exchangers with respect to the total annual costs by a cuckoo search algorithm. The total annual cost is considered as the optimization objective so as to obtain economic heat exchanger structures. The performance of the CSA algorithm is further compared with various algorithm representative of the state of the art in heat exchanger optimi

Psychotic symptoms in frontotemporal dementia: a diagnostic dilemma?

ABSTRACT Background: Frontotemporal dementia (FTD) constitutes a spectrum of neurodegenerative disorders associated with degeneration of, predominantly, the frontal and temporal lobes. The clinical heterogeneity is evident, and early diagnosis is a challenge. The primary objectives were to characterize psychotic symptoms, initial clinical diagnoses and family history in neuropathologically verifie

Effects on cognitive and clinical insight with the use of Guided Self-Determination in outpatients with schizophrenia: A randomized open trial.

Poor insight has a negative impact on the outcome in schizophrenia; consequently, poor insight is a logical target for treatment. However, neither medication nor psychosocial interventions have been demonstrated to improve poor insight. A method originally designed for diabetes patients to improve their illness management, Guided Self-Determination (GSD), has been adapted for use in patients with

Electron microscopy imaging of proteins on gallium phosphide semiconductor nanowires

We have imaged GaP nanowires (NWs) incubated with human laminin, serum albumin (HSA), and blood plasma using both cryo-transmission electron microscopy and synchrotron based X-ray photoemission electron microscopy. This extensive imaging methodology simultaneously reveals structural, chemical and morphological details of individual nanowires and the adsorbed proteins. We found that the proteins bi

Soft X-ray induced oxidation on acrylic acid grafted luminescent silicon quantum dots in ultrahigh vacuum

Water soluble acrylic acid grafted luminescent silicon quantum dots (Si-QDs) were prepared by a simplified method. The resulting Si-QDs dissolved in water and showed stable strong luminescence with peaks at 436 and 604 nm. X-ray photoelectron spectroscopy (XPS) was employed to examine the surface electronic states after the synthesis. The co-existence of the Si2p and C1s core levels infers that th

A semantic theory of word classes

Within linguistics a word class is defi ned in grammatical terms as a set of words that exhibit the same syntactic properties. In this paper the aim is to argue that the meanings of different word classes can be given a cognitive grounding. It is shown that with the aid of conceptual spaces, a geometric analysis can be provided for the major word classes. A universal single-domain thesis is propos

The Finnish Homelessness Strategy – An International Review

Abstract in Finnish Arvioinnin kohteena oli vuosien 2008–2011 ja 2012–2015 aikana toteutettu pitkäaikaisasunnottomuuden vähentämisohjelmakokonaisuus, Paavo I ja Paavo II. Arvioinnissa keskityttiin ohjelmakokonaisuuteen ja sen eri osa-alueisiin näkökulmana asunto ensin -mallin toteuttaminen suomalaisessa yhteiskunnassa. Arviointiraportissa on kuvattu Iso-Britannian, Ruotsin ja USA:n asunnottomuustyThe review covered the whole of the programme to reduce long-term homelessness implemented during 2008–2011 and 2012–2015, Paavo I and Paavo II. The review focused on the programme as a whole as well as its different aspects from the point of view of implementing the Housing First model in Finnish society. The review report described work on homelessness done in the United Kingdom, Sweden and the