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Tumor Necrosis Factor Receptor 1 and 2 Are Associated With Risk of Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: Raised plasma concentrations of tumor necrosis factor receptors (TNFR) have been linked to arterial stiffness, cerebral microbleeds, and vascular events. The aim of this study was to investigate the association of circulating levels of TNFR1 and TNFR2 with risk for future intracerebral hemorrhage (ICH).METHODS: The population-based MDCS cohort (Malmö Diet and Cancer Study;

The Ambivalent Potentiality of Vulnerability : Museum Pedagogy in Exhibitions on Difficult Matters and its Ethical Implications

The aim of this dissertation is to critically investigate and problematize how museum exhibitions on Difficult Matters, like war and sexual violence, can be designed in order to contribute to teaching-learning relations between museum and visitor, which may transform existing perceptions of self, others, and the world and evoke a deepened sense of responsibility in the viewers, i.e. an ethical tra

The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

The non-receptor tyrosine kinase LCK belongs to the SRC family of kinases. SRC family kinases are proto-oncogenes that have long been known to play key roles in cell proliferation, motility, morphology and survival. Here we show that LCK regulates the function of the type III receptor tyrosine kinase FLT3 in murine pro-B cells. We observed that expression of LCK significantly enhances the colony f

Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Natriuretic peptides (NPs) are important hormones that regulate multiple cellular functions including cardiovascular physiology. In the heart, two natriuretic peptide receptors NPR1 and NPR2 act as membrane guanylyl cyclases to produce 3′,5′-cyclic guanosine monophosphate (cGMP). Although both receptors protect from cardiac hypertrophy, their effects on contractility are markedly different, from l

Breathlessness and sexual activity in older adults : The Australian Longitudinal Study of Ageing

Sexual activity is important to older adults (65 +). Breathlessness affects about 25% of older adults but impact on sexual activity is unknown. We evaluated the relationships between breathlessness and sexual inactivity and self-reported health among older community-dwelling adults in the Australian Longitudinal Study of Ageing. Associations between self-reported breathlessness (hurrying on level

Impact of surface properties on morphology of spray-dried milk serum protein/lactose systems

This study investigated milk serum protein concentrate/lactose systems with varying ratios and how the morphology of the spray-dried particles of these systems could be described by the surface properties of the feed as well as the protein surface coverage of the particles. An extrapolation of the surface pressure of the feed to 0.3 s, the approximate time for molecular diffusion in an atomised dr

Search for Higgs boson decays into pairs of light (pseudo)scalar particles in the γγjj final state in pp collisions at s=13TeV with the ATLAS detector

This Letter presents a search for exotic decays of the Higgs boson to a pair of new (pseudo)scalar particles, H→aa, where the a particle has a mass in the range 20–60 GeV, and where one of the a bosons decays into a pair of photons and the other to a pair of gluons. The search is performed in event samples enhanced in vector-boson fusion Higgs boson production by requiring two jets with large inva

The power of love : Towards an interdisciplinary and multi-theoretical feminist love studies

Although love in some form is arguably as old as humankind, many scholars judge that it has never been as socially and existentially decisive as it is in contemporary western societies (Bauman 2003; Beck and Beck-Gernsheim 1995; Ferry 2013; Giddens 1992; Gunnarsson 2014a; Illouz 2012; Jónasdóttir 1994, 2011; Kaufmann 2011; Luhmann 1998; May 2011). The loosening of collective and role-based modes o

The experiences of pre- and in-hospital care in patients with hip fractures : A study based on Critical incidents

Background: Hip fractures are described to have a significant impact on patients' well-being and different fast-track concepts could result in a reduction of the patient's psychological and emotional reactions before pre- and intrahospital care. Aims and objectives: This study aimed to elucidate perceived situations of significance experienced by patients with hip fracture during the prehospital-

Search for heavy resonances decaying to a W or Z boson and a Higgs boson in the qq¯(′)bb¯ final state in pp collisions at s=13 TeV with the ATLAS detector

A search for heavy resonances decaying to a W or Z boson and a Higgs boson in the qq¯(′)bb¯ final state is described. The search uses 36.1 fb−1 of proton–proton collision data at s=13 TeV collected by the ATLAS detector at the CERN Large Hadron Collider in 2015 and 2016. The data are in agreement with the Standard Model expectations, with the largest excess found at a resonance mass of 3.0 TeV wit

Graphene Ribbon Growth on Structured Silicon Carbide

Structured Silicon Carbide was proposed to be an ideal template for the production of arrays of edge specific graphene nanoribbons (GNRs), which could be used as a base material for graphene transistors. We prepared periodic arrays of nanoscaled stripe-mesas on SiC surfaces using electron beam lithography and reactive ion etching. Subsequent epitaxial graphene growth by annealing is differentiated

Label-free enrichment of cancer cells using negative selection (depletion) of wbcs with elastomeric negative acoustic contrast particles and acoustophoresis

In an effort to bioengineer elastomeric particles (EPs), with negative acoustic contrast factor, to capture cells, we have successfully functionalized EPs with anti-human CD45 antibodies that enable capturing of WBCs from human RBC lysed blood samples. We demonstrate that the negative selection of WBCs with EPs and acoustophoresis can be employed to reduce WBC contamination while enriching label-f

Jet energy scale measurements and their systematic uncertainties in proton-proton collisions at s =13 TeV with the ATLAS detector

Jet energy scale measurements and their systematic uncertainties are reported for jets measured with the ATLAS detector using proton-proton collision data with a center-of-mass energy of s=13 TeV, corresponding to an integrated luminosity of 3.2 fb-1 collected during 2015 at the LHC. Jets are reconstructed from energy deposits forming topological clusters of calorimeter cells, using the anti-kt al

More detailed data does not always raise the costs : Experience from a Swedish cost of alcohol study

The aim is to investigate the effect of availability and level of detail of data on cost estimates of alcohol consumption. Using the recent Swedish cost of alcohol study as baseline, limitations on data are applied, forming two models. The costs of alcohol in Sweden are re-estimated in the two models and compared to the baseline, to establish the magnitude and direction of the bias resulting from

HIV/AIDS-GDP Nexus? : Evidence from panel-data for African countries

To test potential bilateral causalities relation between HIV-AIDS mortality and GDP, we propose a simple Granger noncausality test for heterogeneous panel data models. 44 African countries are selected for annual pooled data from 1990 to 2009. Results are presented for the heterogeneous noncausality hypothesis (HENC), which tests, for each cross-section unit, the nullity of all the coefficients of

Swedish experience-based value sets for EQ-5D health states

PurposeTo estimate Swedish experience-based value sets for EQ-5D health states using general population health survey data.MethodsApproximately 45,000 individuals valued their current health status by means of time trade off (TTO) and visual analogue scale (VAS) methods and answered the EQ-5D questionnaire, making it possible to model the association between the experience-based TTO and VAS values

The lipolytic degradation of highly structured cubic micellar nanoparticles of soy phosphatidylcholine and glycerol dioleate by phospholipase A2 and triacylglycerol lipase

The effects of different lipolytic enzymes on the structure of lipid liquid crystalline nano-particles (LCNP) have been investigated by cryogenic transmission electron microscopy (cryo-TEM) and synchrotron small angle X-ray diffraction (SAXD). Here we used highly structured cubic micellar (Fd3m) nanoparticles of 50/50 (wt%/wt%) soy phosphatidyl choline (SPC)/glycerol dioleate (GDO) as substrate. T