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Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration

PURPOSE: The chemokine receptor CXCR3 has been strongly related to inhibition of angiogenesis. The purpose of this study was to investigate the association between expression of CXCR3 on peripheral blood leukocytes and age-related wet macular degeneration. Furthermore, we measured the plasma concentration of chemokines CXCL9 to -11.METHODS: The study group consisted of patients with age-related ma

Twin-scroll turbocharger turbine stage evaluation of experimental data and simulations

In this study a novel comparison of CFD, measured data and a ID-model is presented for a Twin-scroll turbocharger turbine stage. Both full and single admission flow divisions were taken into consideration and shown to represent "on-engine" conditions in the high and low engine rpm range respectively for a heavy-duty 6-cylinder diesel engine. With this in mind, the turbine stage was evaluated for e

ChPT parameters from τ-decay data

Using the updated ALEPH V-. A spectral function from τ decays, we determine the lowest spectral moments of the left-right correlator and extract dynamical information on order parameters of the QCD chiral symmetry breaking. Uncertainties associated with violations of quark-hadron duality are estimated from the data, imposing all known short-distance constraints on a resonance-based parametrization

Spectral density analysis of the chiral transition in nf=4 finite temperature QCD

We apply the spectral density reweighting technique to the analysis of the chiral phase transition in finite-temperature lattice quantum chromodynamics (QCD) with four flavors of dynamical staggered fermions and mqa=0.025. Our simulations were performed using the hybrid Monte Carlo method for LtL3 lattices with Lt=4 and L=6, 8 and 10. We calculate partition function zeros, as well as the maxima of

Impact of sediment supply on decadal-scale dune evolution — Analysis and modelling of the Kennemer dunes in the Netherlands

This study investigates the impact of beach sediment supply on dune volume evolution through data analysis and model simulations of the Kennemer dunes in the Netherlands. A cross-shore sediment transport model (the CS-model) is applied with local time-averaged longshore sediment transport gradients derived from bathymetric and topographic observations. The model is used to study the relative impor

Microfluidic electronic tongue

Fast, simple inspection of liquids such as coffee, wine and body fluids is highly desirable for food, beverage and clinical analysis. Electronic tongues are sensors capable of performing quantitative and qualitative measurements in liquid substances using multivariate analysis tools. Earlier attempts to fulfil this task using only a few drops (microliters) of sample did not yield rational results

Chitosan does not inhibit enzymatic action of human pancreatic lipase in Langmuir monolayers of 1,2-didecanoyl-glycerol (DDG)

In this study, we tested the hypothesis according to which chitosan reduces lipid digestion by blocking the access of lipases to ingested fat. Because lipase action takes place mostly at interfaces, we produced Langmuir films of 1,2-didecanoyl-glycerol (DDG), which is the substrate for human pancreatic lipase (HPL). The experimental assays were carried out in acidic medium, at pH 3.0, to ensure th

Physical vapor deposited thin films of lignins extracted from sugar cane bagasse : Morphology, electrical properties, and sensing applications

The concern related to the environmental degradation and to the exhaustion of natural resources has induced the research on biodegradable materials obtained from renewable sources, which involves fundamental properties and general application. In this context, we have fabricated thin films of lignins, which were extracted from sugar cane bagasse via modified organosolv process using ethanol as org

Energy efficient and moisture safe row houses in Sweden

This project consists of a thorough study of an energy efficient and moisture safe row-house, located in the Nordic climate of Sweden. Climate and site analysis, building scale design decisions and finally the evaluation and optimization of its energy performance were different steps of a holistic process aiming at the architectural quality, energy efficiency, comfort and the well-being of users.

Test-retest repeatability of human speech biomarkers from static and real-time dynamic magnetic resonance imaging

Static anatomical and real-time dynamic magnetic resonance imaging (RT-MRI) of the upper airway is a valuable method for studying speech production in research and clinical settings. The test-retest repeatability of quantitative imaging biomarkers is an important parameter, since it limits the effect sizes and intragroup differences that can be studied. Therefore, this study aims to present a fram

Predictive risk mapping of human leptospirosis using support vector machine classification and multilayer perceptron neural network

Leptospirosis is a zoonotic disease found wherever human is in direct or indirect contact with contaminated water and environment. Considering the increasing number of cases of this disease in the northern part of Iran, identifying areas characterized by high disease incidence risk can help policy-makers develop strategies to prevent its further spread. This study presents an approach for generati

Statistics conditioned to isoscalar surfaces in highly turbulent premixed reacting systems

The paper aims at clarifying some issues associated with evaluation of surface-averaged quantities in Direct Numerical Simulation (DNS) of a turbulent reacting flow. For a quantity ϕ(t, x) averaged over an isosurface c(t,x)=c^ of a reaction progress variable c, there exist at least two different definitions of surface averages; an area-weighted surface average 〈ϕ〉 s | c^,t and an unweighted

Repeat procedures for recurrent colorectal liver metastases : Analysis of long-term liver regeneration and outcome

Background and aim: Repeat hepatectomy is increasingly performed for the management of recurrent colorectal liver metastases (CRLM). The aim of this study was to evaluate longterm functional liver volume (FLV) after a second hepatic procedure and to measure survival outcome. Methods: In this retrospective cohort study, patients treated for recurrent CRLM in the years 2005-2015 at two liver centers