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Chitosan does not inhibit enzymatic action of human pancreatic lipase in Langmuir monolayers of 1,2-didecanoyl-glycerol (DDG)

In this study, we tested the hypothesis according to which chitosan reduces lipid digestion by blocking the access of lipases to ingested fat. Because lipase action takes place mostly at interfaces, we produced Langmuir films of 1,2-didecanoyl-glycerol (DDG), which is the substrate for human pancreatic lipase (HPL). The experimental assays were carried out in acidic medium, at pH 3.0, to ensure th

Physical vapor deposited thin films of lignins extracted from sugar cane bagasse : Morphology, electrical properties, and sensing applications

The concern related to the environmental degradation and to the exhaustion of natural resources has induced the research on biodegradable materials obtained from renewable sources, which involves fundamental properties and general application. In this context, we have fabricated thin films of lignins, which were extracted from sugar cane bagasse via modified organosolv process using ethanol as org

Energy efficient and moisture safe row houses in Sweden

This project consists of a thorough study of an energy efficient and moisture safe row-house, located in the Nordic climate of Sweden. Climate and site analysis, building scale design decisions and finally the evaluation and optimization of its energy performance were different steps of a holistic process aiming at the architectural quality, energy efficiency, comfort and the well-being of users.

Test-retest repeatability of human speech biomarkers from static and real-time dynamic magnetic resonance imaging

Static anatomical and real-time dynamic magnetic resonance imaging (RT-MRI) of the upper airway is a valuable method for studying speech production in research and clinical settings. The test-retest repeatability of quantitative imaging biomarkers is an important parameter, since it limits the effect sizes and intragroup differences that can be studied. Therefore, this study aims to present a fram

Predictive risk mapping of human leptospirosis using support vector machine classification and multilayer perceptron neural network

Leptospirosis is a zoonotic disease found wherever human is in direct or indirect contact with contaminated water and environment. Considering the increasing number of cases of this disease in the northern part of Iran, identifying areas characterized by high disease incidence risk can help policy-makers develop strategies to prevent its further spread. This study presents an approach for generati

Statistics conditioned to isoscalar surfaces in highly turbulent premixed reacting systems

The paper aims at clarifying some issues associated with evaluation of surface-averaged quantities in Direct Numerical Simulation (DNS) of a turbulent reacting flow. For a quantity ϕ(t, x) averaged over an isosurface c(t,x)=c^ of a reaction progress variable c, there exist at least two different definitions of surface averages; an area-weighted surface average 〈ϕ〉 s | c^,t and an unweighted

Repeat procedures for recurrent colorectal liver metastases : Analysis of long-term liver regeneration and outcome

Background and aim: Repeat hepatectomy is increasingly performed for the management of recurrent colorectal liver metastases (CRLM). The aim of this study was to evaluate longterm functional liver volume (FLV) after a second hepatic procedure and to measure survival outcome. Methods: In this retrospective cohort study, patients treated for recurrent CRLM in the years 2005-2015 at two liver centers

The MAX IV imaging concept

The MAX IV Laboratory is currently the synchrotron X-ray source with the beam of highest brilliance. Four imaging beamlines are in construction or in the project phase. Their common characteristic will be the high acquisition rates of phase-enhanced images. This high data flow will be managed at the local computing cluster jointly with the Swedish National Computing Infrastructure. A common image

Plant survival in Iceland during periods of glaciation?

Aim: The paper addresses the classical question of possible plant survival in Iceland during the last glacial period in the light of a palaeobotanical record from northern Iceland, spanning the period 11,300-9000 BP, including the Younger Dryas stadial. We review the Late Cenozoic fossil plant record, the past debate on glacial plant refugia in Iceland, and the evidence for ice-free areas during t

Updated determination of chiral couplings and vacuum condensates from hadronic τ decay data

We analyze the lowest spectral moments of the left-right two-point correlation function, using all known short-distance constraints and the recently updated ALEPH V-A spectral function from τ decays. This information is used to determine the low-energy couplings L10 and C87 of chiral perturbation theory and the lowest-dimensional contributions to the operator product expansion of the left-right co

Mass reconstruction with a neural network

A feed-forward neural network method is developed for reconstructing the invariant mass of hadronic jets appearing in a calorimeter. The approach is illustrated in W→qq, where W-bosons are produced in pp reactions at SPS collider energies. The neural network method yields results that are superior to conventional methods. This neural network application differs from the classification ones in the

The axial anomaly and the lattice Dirac sea

In the hamiltonian formulation of fermions coupled to external gauge fields, the axial anomaly has a simple physical interpretation in terms of level shifting at the top of the Dirac sea. We apply this formalism to lattice QED in 1 + 1 and 3 + 1 dimensions, in order to study how the lattice regulation and small fermion mass affect the picture. For a simple choice of the E and B fields, it is possi

Industrial applications of ultrafiltration in the pharmaceutical biotechnology

In pharmaceutical biotechnology, ultrafiltration with diafiltration for recovery of fermentation products on an industrial scale is now the state-of-the-art technology. To optimise this process, DSS has developed two new concepts: (1) an optimised control system for constant permeate concentration even at varying feed streams and (2) continuous counter-current diafiltration to significantly reduce

Nerve-dependent and -independent tenascin expression in the developing chick limb bud

The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Tenascin accumulates along developing peripheral nerves as they leave the spinal cord and enter the limb mesenchyme (Wehrle and Chiquet, Development 110, 401-415, 1990). Here we found that most but not all tenascin deposited along growing nerves is of glial origin. By in situ hybridization with

Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine ClC-K and CLC tran