Complement C3 was originally regarded as a serum effector protein, although recent data has emerged suggesting that intracellular C3 can also regulate basic cellular processes. Despite the growing interest in intracellular C3 functions, the mechanism behind its generation has not been demonstrated. In this study we show that C3 can be expressed from an alternative translational start site, resulti

During a voluntary contraction, motor units (MUs) fire a train of action potentials, causing summation of the twitch forces, resulting in fused or unfused tetanus. Twitches have been important in studying whole-muscle contractile properties and differentiation between MU types. However, there are still knowledge gaps concerning the voluntary force generation mechanisms. Current methods rely on the

Active transport (walking and biking) has significant environmental, health, and social benefits. Despite the importance of active transport, theoretically framed research has not sufficiently considered what makes consumers walk or bike based on activity types, particularly in an Asian context. This is an important topic as it helps provides a basis for better targeted marketing and promotion to

Many economic models assume that random variables follow normal (Gaussian) distributions. Yet, real-world variables may be non-normally distributed. How sensitive are these models' predictions to distribution misspecifications? This paper addresses the question in the context of linear-quadratic beauty contests played by rationally inattentive players. It breaks with the assumption that the (commo

This study aims to verify the nutritional value of the fatty acid (FA) profile of three fruits claimed to confer health benefits (goji berry, white mulberry, and cranberry), often referred to as “superfruits”, over three common fruits (banana, apple, and strawberry). Nineteen different FAs, ranging in concentrations between 0.018 and 9.4 mg/g dry sample were detected. Levels of very long-chained F

To achieve sustainable metal-free electron-Fenton, N self-doped biochar air-cathode (BCAC) was prepared by pyrolyzing coffee residues. During the pyrolysis process, the endogenous N transformed from edge-doping to graphite-doping. Particularly, N vacancies started to evolve when the peak temperature exceeded 700 °C. A high Tetracycline removal rate of 70.42% was obtained on the BCAC at the current

Purpose: Acute trauma-related rotator cuff tears are believed to have better healing potential than chronic tears due to less degenerative changes of the tendons. However, the histopathological condition of tendons from trauma-related tears is not well investigated. The purpose of this study was to explore specific histopathological features in tendons from acute trauma-related full-thickness rota

Summary: In this prospective study in Swedish elderly men, PAD based on an ABI < 0.9 was associated with an increased risk of hip fracture, independent of age and hip BMD. However, after further adjustments for comorbidity, medications, physical function, and socioeconomic factors, the association diminished and was no longer statistically significant. Introduction: To examine if peripheral arteri

On bounded B-regular domains, we study envelopes of plurisubharmonic functions bounded from above by a function ϕ which is continuous in the extended reals on the closure of the domain. For ϕ satisfying certain additional criteria limiting its behavior at the singularities, we establish a set where the Perron–Bremermann envelope Pϕ is guaranteed to be continuous. This result is a generalization of

The purpose of the EANM Dosimetry Committee is to provide recommendations and guidance to scientists and clinicians on patient-specific dosimetry. Radiopharmaceuticals labelled with lutetium-177 (177Lu) are increasingly used for therapeutic applications, in particular for the treatment of metastatic neuroendocrine tumours using ligands for somatostatin receptors and prostate adenocarcinoma with sm

Objectives: We explored the prevalence of health complaints subjectively associated with static magnetic field (SMF) and acoustic noise exposure among MR radiographers in Sweden, using CT radiographers as a control group. Additionally, we explored radiographers’ use of strategies to mitigate adverse health effects. Methods: A cross-sectional survey was sent to all hospitals with MR units in Sweden

Background & Aims: There is substantial inter-individual variability in the risk of non-alcoholic fatty liver disease (NAFLD). Part of which is explained by insulin resistance (IR) (‘MetComp’) and part by common modifiers of genetic risk (‘GenComp’). We examined how IR on the one hand and genetic risk on the other contribute to the pathogenesis of NAFLD. Methods: We studied 846 individuals: 49

Antibiotic residues are being continuously recognized in the aquatic environment and in food. Though the concentration of antibiotic residues is typically low, adverse effects on the environment and human health have been observed. Hence, an efficient method to determine numerous antibiotic residues should be simple, inexpensive, selective, with high throughput and with low detection limits. Liqui

The Personality Differentiation by Intelligence Hypothesis (PDIH) predicts larger trait-variances, and smaller across-trait covariances for individuals with higher intelligence. We tested these predictions using multiple-group confirmatory factor analyses (MG-CFA), while controlling for the potential confound of systematic method variance related to reversed items using a correlated trait, correla

Excessive avoidance causes functional impairment and maintains anxiety disorders. In the laboratory, approach-avoidance conflict tasks (AACT) can be used to study approach-avoidance behavior in mixed outcome situations (i.e., the same behavior entails both aversive and rewarding consequences). We tested the feasibility of a novel, internet-delivered AACT (iAACT) by conceptually replicating results

During laser powder bed fusion (L-PBF), materials experience cyclic re-heating as new layers are deposited, inducing an in situ tempering effect. In this study, the effect of this phenomenon on the tempering of martensite during L-PBF was examined for Fe-0.45C steel. Detailed scanning electron microscopy, transmission electron microscopy, atom probe tomography, and hardness measurements indicated

Background: Metabolic syndrome (MetS) is associated with high cardiovascular morbidity and mortality, and endothelial dysfunction is an early pathogenetic event in the MetS. Lifestyle changes and pharmacological intervention might partly restore endothelial function in MetS. Whereas an optimal non-invasive test for endothelial dysfunction is still being sought, the aim of this study was to assess