In this thesis we will explore methods to generate random numbers from any distribution. The basic idea behind generating random numbers is to use a mathematical sequence for which it should be impossible to guess what the next number is without knowing exactly how the sequence is generated. Although any hard to guess sequence would work, this thesis focuses on the linear congruential sequence, $

OBJECTIVE: Niemann-Pick Type C (NPC) is a genetic neurodegenerative lysosomal storage disorder commonly associated with psychiatric symptoms and delays to accurate diagnosis and treatment. This study investigated biomarker levels and diagnostic utility of plasma neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in NPC compared to healthy controls. METHODS: Patients with NP

BackgroundSocial and geographical inequity in access to primary healthcare is an ongoing concern in Sweden. Digital care can potentially decrease geographical inequity. This study aimed to evaluate how urbanicity affects the utilization of a public digital primary healthcare service - PHC Online.MethodsWe performed an ecological cross-sectional study of 4,482 PHC Online visits grouped by 83 public

Similar to systematic reviews (SRs) in clinical fields, preclinical SRs address a specific research area, furnishing information on current knowledge, possible gaps, and potential methodological flaws of study design, conduct, and report. One of the main goals of preclinical SRs is to identify aspiring treatment strategies and evaluate if currently available data is solid enough to translate to cl

Introduction: Neurofilament light chain (NfL), a blood biomarker of neuronal injury, shows promise in distinguishing neurodegenerative disorders from psychiatric conditions. This is especially relevant in psychosis, given neurological conditions such as autoimmune encephalitis and Niemann Pick Type C disease (NPC) may initially present with psychotic symptoms. Whilst NfL levels have been studied i

The ability of machine learning (ML) techniques to forecast the shear strength of corroded reinforced concrete beams (CRCBs) is examined in the present study. These ML techniques include artificial neural networks (ANN), adaptive-neuro fuzzy inference systems (ANFIS), decision tree (DT) and extreme gradient boosting (XGBoost). A thorough databank with 140 data points about the shear capacity of CR

OBJECTIVE: The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are inflammatory disorders with ANCA autoantibodies recognising either proteinase 3 (PR3-AAV) or myeloperoxidase (MPO-AAV). PR3-AAV and MPO-AAV have been associated with distinct loci in the human leucocyte antigen (HLA) region. While the association between MPO-AAV and HLA has been well characterised in East A

Due to the COVID-19 outbreak, industries have gained a thrust on contactless processing for computing technologies and industrial automation. Cloud of Things (CoT) is one of the emerging computing technologies for such applications. CoT combines the most emerging cloud computing and the Internet of Things. The development in industrial automation made them highly interdependent because the cloud c

In this chapter, I address the “containment” of meaning in relation to questions of authorship (or lack of authorship) in biblical studies. By revisiting Roland Barthes’ and Michel Foucault’s critiques of the author figure, I suggest that the implication for biblical studies is the opening of meaning-making beyond the figure of the author in his or her original context. Engaging with Brennan Breed

The encoding of goal-oriented motion events varies across different languages. Speakers of languages without grammatical aspect (e.g., Swedish) tend to mention motion endpoints when describing events (e.g., “two nuns walk to a house”) and attach importance to event endpoints when matching scenes from memory. Speakers of aspect languages (e.g., English), on the other hand, are more prone to direct

This opening article introduces the reader to current topics in research on language and thought in monolingual speakers and second language (L2) learners, with particular attention to the domain of motion. The article also delineates the rationale that underlies the special issue at hand, and provides a contextualisation of the individual contributions. It is argued that the centrality of motion

This study aims to analyze how corruption affects the relationship between international trade and child development. Geographically, this study focuses on Sub-saharan Africa, since it has the highest levels of child mortality as well as the highest perceived corruption levels in the world. To evaluate this relationship, a fixed-effects model with robust standard errors has been implemented. The p

This study aims to analyse how the competition in the Swedish banking market affects major banks´ net interest income, which has increased dramatically over the past two years. To gain a broader understanding of factors affecting the net interest income of the Swedish major banks, this study has identified eight independent variables that according to prior research determine the net interest inco

The 2010s have raised questions about the influence of small central banks in an integrated economy. This thesis investigates the efficacy of the Swedish Riksbank and the effect of economic integration since the adoption of a floating exchange rate in 1993. Theoretically, I examine how financial integration and trade may impact the Mundell-Fleming trilemma. To investigate the impact of integration

This thesis investigates the inflationary impact of the European Electricity Market on its member countries, including the EU28, Norway, and Switzerland, from 2003 to 2019. The research question particularly focuses on whether this market impacts the level of inflation in its net exporting member countries. Utilising two panel data regression models, we explore the market's impact on the rate

This thesis examines the impact of the European Union's development aid on export and import levels in Sub-Saharan Africa, focusing on the role of democracy levels in the recipient countries. Using a multiple regression model with panel data from 1990 to 2018 across 27 countries, the study assesses the influence of the EU’s aid on trade, while also considering the factors GDP, population, life

This paper examines the effect of the recurrent tax on immovable property on wealth distribution. It also investigates how the wealth distributive effect of property prices is affected by the homeownership rate in a country. Data on the mean to median wealth ratio, tax sizes, property prices, homeownership rate, and economic freedom of 36 OECD member countries over the years 2000-2021 are used to