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Hur påverkar Herpes Simplex Virus vilka gener som uttrycks i den infekterade cellen? Herpes Simplex Virus har förmågan att ändra vilka gener som uttrycks i en infekterad cell. Detta gör att viruset får verktyg att ändra på proteinerna på den infekterade cellens yta. Vi har undersökt hur den lyckas med detta genom att blockera olika signalvägar och mäta hur mycket RNA av olika gener som produceratHerpes Simplex Virus type 1 (HSV-1) is a virus infecting over 90 % of the population. It causes latent infections in nerve cells and can upon reactivation travel along the neurons and cause lytic infections with painful blisters as a result. HSV-1 infects multiple cell types, fibroblasts and T-cells among others. During infection HSV-1 is known to downregulate the transcription of many of the gene

The labour migration to the GCC states and Qatar in particular remains substantial. 94 % of Qatari labour force is migrant workers. After Qatar was awarded to host the FIFA World Cup 2022, migration is on the rise and Qatar is expected to welcome at least 1 million workers to build infrastructure for hosting the world-famous event. While Qatar is luring more workers, Asian sending countries are al

The aim of the study was to examine the role of the social worker employed within Malmö psychiatry regarding the social worker’s status and impact on patient care. The social worker’s role within hospital environment is a topic that has been examined many times before. In 2014, Socialstyrelsen released a report about introducing a license for social workers employed within hospital environments. T

The goal of this study, through the use of mainly an organizational theory perspective, is to examine the problems and obstacles in the cooperative work between social workers and other social actors in cases involving children at risk. The aim is to highlight problems that exist in social secretaries cooperative work and to find ways to understand them. The result showed that poor professional in

The aim of this study was to examine how the guidelines of interprofessional cooperation regarding clients with substance drug abuse problems and mental illness are implemented between the organisations of social services and healthcare. The study was performed in four Swedish small municipalities. The survey is based on the perspective of the staff from social service and also examines what strat

Informationssamhällets framväxt bidrar med nya utmaningar för rättsliga regleringar utformade efter traditionella gränser när dessa ska upprätthållas i en gränslös digital miljö. Digitaliseringen av samhället ger upphov till rättsfrågor som inte nödvändigtvis är nya men som placerar dessa i en ny miljö, vilket bidrar till en viss osäkerhet kring rättsläget i många fall. Mot bakgrund av detta behanThe development of the information society brings new challenges to legal constructions created in a landscape of traditional boundaries when these are to be upheld and enforced in a borderless digital environment, mainly due to a technical development that is constantly pushing the boundaries. An increased digitalisation of the society gives rise to not necessarily new legal questions but put the

The aim of this study was to examine which discourses that appear in the construction of honour related violence in swedish policy documents. This study focus on the construction of honour related violence in terms of it’s forms of expression as well as it’s underlying causes. We also focus on the significance of the categories gender and ethnicity in the construction of honour related violence. T

Varumärkets växande betydelse för företagens framgång och värde, de effekter som varumärkesrätten har för en sund marknadskonkurrens och det stundande europeiska varumärkesrättsliga reformpaketet skapar flertalet potentiella infallsvinklar för en juridisk framställning. En av dessa är den grundläggande regeln om användningstvång, i synnerhet kravet på verkligt bruk däri, som ständigt varit föremålThe continuous growing importance of trademarks in relation to the value and success of a business, the effects of trademark law on sound market competition and the forthcoming legislative EU trademarks reform package create several potential judicial aspects. One aspect is the use requirement and in particular the genuine use requirement, which has been the subject of constant debate. The use req

Sandvik Coromant is the market leader of producing tools for advanced metal cutting. The tools are produced in cemented carbide, however Sandvik Coromant does not produce tools for machining cemented carbide. The aim of the thesis was to perform cutting tests in cemented carbide with diamond tools to investigate if the binder content affected the machinability of the process. The wear tests were

Efter avgöranden från både Europadomstolen och Högsta domstolen, där staten ålagts skadeståndsansvar för ideell skada för kränkningar av fri- och rättigheter enligt Europakonventionen, har en diskussion uppstått kring huruvida ett ansvar för det allmänna bör gälla även vid kränkningar av fri- och rättigheter enligt 2 kap. regeringsformen. Genom rättsfallet NJA 2014 s. 323 ålade Högsta domstolen utAfter rulings from both the European Court of Human Rights and the Swe-dish Supreme Court, where the Government was imposed liability for non-pecuniary damage for the violations of rights and freedoms guaranteed un-der the European Convention on Human Rights, a discussion has arisen about whether the responsibility for the Government for such damage should also apply to violations of rights and fr

The purpose of this project was to investigate fast photoneutron production from a series of materials commonly used for backing neutron beam guides. Fast neutrons were knocked out of these materials by exposing them to to high-energy photons at the Tagged-Photon Facility at MAX-lab in Lund, Sweden. Liquid scintillator detectors at different angles around the targets registered the photoknockout n

This thesis presents a comparison between implementations of the inverse square root function, using two approximation algorithms; Harmonized Parabolic Synthesis and the Newton-Raphson Method. The input is a 15 bit fixed-point number, the range of which is selected so that the implementation is suitable for use as a block implementing the inverse square root for floating-point numbers, and the des

Sedan 2005 har uppehållstillstånd beviljats en utlänning om det vid en samlad bedömning av utlänningens situation föreligger sådana synnerligen ömmande omständigheter att han eller hon bör tillåtas stanna i Sverige. I juli 2014 trädde en bestämmelse i kraft som stadgar att barn kan få stanna i Sverige om det föreligger särskilt ömmande omständigheter. Uppsatsens syfte är att utreda rättsläget för Since 2005 an alien can be granted residence permit if, after an overall assessment of the alien’s situation, there are such exceptionally distressing circumstances that he or she should be allowed to stay in Sweden. In July 2014 a provision came in force which stipulates that children may stay in Sweden if there are particularly distressing circumstances. The purpose of this thesis is to determin

High-throughput screening is one of the most extensively used methods for the identification of molecules of interest during early stages of drug development projects. It is however subject to many artifacts due to various mechanisms. Aggregation and redox cycling are examples of mechanisms of unspecific inhibition that make a large number of compounds appear as active in several high throughput s

Framställningen syftar till att undersöka hur HD:s tolkning av kommersiella entreprenadavtal utvecklats. För att uppnå syftet utreds hur entreprenadavtal ska tolkas, hur praxis har utvecklats på området sedan år 2000 samt vilka konsekvenser utvecklingen kan medföra. Entreprenadavtal är inte lagreglerade i svensk rätt och sparsamt behandlade i doktrin. Termen kan förstås som ett avtal där entrepreThe purpose of the thesis is to examine how the interpretation of construction contracts has evolved by the Supreme Court. The thesis examines how the contracts should be interpreted, how the precedents have developed in the field since year 2000 and what consequences the development could bring. Construction contracts are not regulated by Swedish law and are rarely treated in the doctrine. A con

The theme for this analysis comes directly as an assignment from Svensk Elitfotboll (SEF) with the purpose to analyze and compare violence crime rate between high risk football matches and festivals. The reason for this is that SEF has come to believe that football matches tend to be described as more dangerous to the public than festivals and therefore giving the whole experience of going to see

En av de mest centrala författningarna på förmögenhetsrättens område är den svenska avtalslagen. Lagen tillkom genom ett juridisk samarbete mellan de nordiska länderna. Den antogs 1915 i Sverige, och därefter även i de övriga nordiska länderna. Då lagen nu uppnått en hög ålder väcks frågan om den behöver reformeras, eller om den än idag fungerar väl i det moderna samhället. Den här uppsatsen syftaOne of the most central acts on commercial matters in Sweden is the Swedish Contract Act. The act was created through a legal cooperation between the Nordic countries. It was adopted in 1915 in Sweden, and afterwards in the other Nordic countries. As the act now has reached an advanced age, the question arises if there is a need for a reformation, or if it still works well in the modern society. T

Internet har inneburit en förändring ur många många aspekter. Tekniken har medfört förändringar för hur vi kommunicerar, samlar in och delar med oss information och material m.m. Denna utveckling har medfört ett flertal intressekonflikter. Det kan handla om att skyddat material, till exempel upphovsrättsskyddad musik, kan spridas utan rättighetsinnehavarens medgivande eller att personuppgifter ellInternet has resulted in changes in many aspects. The technology has brought changes in how we communicate, retrieve and share information and material etc. This development has resulted in several conflicts of interests, that encompass protected material such as copyrighted music that can be shared without the consent of the copyright owner or that private information about an individual is circu

In the last decades one of the main topics in the international intellectual property forum has been the biopiracy issue. Genetic resources and traditional knowledge from developing nations are being misappropriated (i.e. biopiracy), by commercial actors in order to receive patent protection. Developments in genetics and biotechnology have intensified the controversy and attempts were initially so

Sammanfattning Det är ett vanligt fenomen att webbplatser använder sig av cookies för att samla in information, vilken sedan säljs vidare till tredje part i marknadsföringssyfte. Denna teknik fungerar oberoende den fysiska personens geografiska placering i världen. Förfarandet väcker frågor om personlig integritet och individens möjligheter till skydd i ljuset av teknikutvecklingen. FramställningeIt is a common phenomenon that websites use cookies in order to collect information, which thereafter is being sold to a third party for marketing purposes. This technique works regardless of the natural person's geographical location in the world. The process raises issues in relation to privacy protection and the individual's protection in light of the technological development. The purp