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Hawaiiskjortans estetik
En kulturhistorisk perspketivering med plagget Hawaiiskjortan i fokus. Dels beskrivs Hawaiiskjortan som sådan, historisk etablering, i ett internetaionellt såväl som inrikes svenskt läge; dels förs resonemang om Hawaiiskjortans symboliska och betydelseproducerande roll i populärkulturen (TV-serier, filmer, musik av olika slag).
SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults and the second most common among children. AML is characterized by aberrant proliferation of myeloid blasts in the bone marrow and impaired normal hematopoiesis. Despite the introduction of new drugs and allogeneic bone marrow transplantation, patients have poor overall survival rate with relapse as the major challeng
Plant diversity enhances ecosystem multifunctionality via multitrophic diversity
Ecosystem functioning depends on biodiversity at multiple trophic levels, yet relationships between multitrophic diversity and ecosystem multifunctionality have been poorly explored, with studies often focusing on individual trophic levels and functions and on specific ecosystem types. Here, we show that plant diversity can affect ecosystem functioning both directly and by affecting other trophic
Natural Concepts and the Economics of Cognition and Communication
This article takes a cognitive approach to natural concepts. The aim is to introduce criteria that are evaluated with respect to how they support the cognitive economy of humans when using concepts in reasoning and communicating with them. I first present the theory of conceptual spaces as a tool for expressing the criteria. Then I introduce the central idea that natural concepts correspond to con
RealTimeTransport: An open-source C++ library for quantum transport simulations in the strong coupling regime
The description of quantum transport in the strong system-reservoir coupling regime poses a significant theoretical and computational challenge that demands specialized tools for accurate analysis. RealTimeTransport is a new open-source C++ library that enables the computation of both stationary and transient transport observables for generic quantum systems connected to metallic reservoirs. It co
A Call to Holiness : Baptism, the Church, and Asceticism in Jerome's Adversus Jovinianum
Scholarship on the Jovinianist controversy has shown that the idea of baptism as deeply transformative lay at the heart of Jovinian's thinking. Scholars have likewise held that Jerome, who through his Adversus Jovinianum is our main source to the ideas of Jovinian, did not acknowledge the ecclesiological concerns on which his opponent's argument was based. This article argues, to the contrary, tha
Multi-hazard life-cycle consequence analysis of deteriorating engineering systems
Probabilistic life-cycle consequence (LCCon) analysis (e.g., assessment of repair costs, downtime, or casualties over an asset's service life) can enable optimal life-cycle management of critical assets under uncertainties. This can lead to effective risk-informed decision-making for future disaster management (i.e., risk mitigation and/or resilience-enhancing strategies/policies) implementation.
Visualization of soil aggregate structures provides insights into their formation mechanisms induced by litter inputs
Soil aggregation is a dynamic process influenced by physical, chemical and biological factors; however, their individual and combined effect on the formation and turnover of aggregates is not well understood. The aim of this study was to examine incorporation of fresh litter inputs of different physicochemical properties including their carbon-to-nitrogen (C/N) ratio – maize (C/N = 12) and straw (
Distribution of infectious and parasitic agents among three sentinel bee species across European agricultural landscapes
Infectious and parasitic agents (IPAs) and their associated diseases are major environmental stressors that jeopardize bee health, both alone and in interaction with other stressors. Their impact on pollinator communities can be assessed by studying multiple sentinel bee species. Here, we analysed the field exposure of three sentinel managed bee species (Apis mellifera, Bombus terrestris and Osmia
Proposal for revised criteria for daylight provision in the European daylight standard based on calculations for Swedish multifamily residential buildings
The European standard EN 17037 was first introduced in 2018 with the aim of encouraging building designers to ensure adequate daylight in buildings. Experience has shown that the standard’s criteria for daylight provision are generally perceived to be too challenging, and this in turn has hindered its implementation in national legislations. This article proposes a revised illuminance-based criter
CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma
Amplification of the MDM2 and CDK4 genes on chromosome 12 is commonly associated with low-grade osteosarcomas. In this study, we conducted high-resolution genomic and transcriptomic analyses on 33 samples from 25 osteosarcomas, encompassing both high- and low-grade cases with MDM2 and/or CDK4 amplification. We discerned four major subgroups, ranging from nearly intact genomes to heavily rearranged
Impact of Al profile in high-Al content AlGaN/GaN HEMTs on the 2DEG properties
Ultra-thin high-Al content barrier layers can enable improved gate control and high-frequency operation of AlGaN/GaN high electron mobility transistors (HEMTs) but the precise composition control is very challenging. In this work, we investigate the compositional profiles of AlxGa1−xN/GaN HEMT structures with targeted Al content in the barrier layer, x = 0.50, 0.70, and 1, and thickness in the sub
Consensus guidelines for the monitoring and management of metachromatic leukodystrophy in the United States
Metachromatic leukodystrophy (MLD) is a fatal, progressive neurodegenerative disorder caused by biallelic pathogenic mutations in the ARSA (Arylsulfatase A) gene. With the advent of presymptomatic diagnosis and the availability of therapies with a narrow window for intervention, it is critical to define a standardized approach to diagnosis, presymptomatic monitoring, and clinical care. To meet the
TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells
Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-Cas9 screen in a human MDS-derived cell line, MDS-L, and identify TOPORS as a loss-of-function target that synergizes with HMAs, reducing leukemic burden and i
Long-Term Risk of Type 2 Diabetes After Preterm Delivery or Hypertensive Disorders of Pregnancy
OBJECTIVE: To examine long-term diabetes risk after preterm delivery or hypertensive disorders of pregnancy in a large population-based cohort. METHODS: This retrospective cohort study included all women with a singleton delivery in Sweden during 1973–2015 and no preexisting diabetes mellitus. Participants were followed up for development of type 2 diabetes identified from nationwide outpatient an
COPDVD : Automated classification of chronic obstructive pulmonary disease on a new collected and evaluated voice dataset
Background: Chronic obstructive pulmonary disease (COPD) is a severe condition affecting millions worldwide, leading to numerous annual deaths. The absence of significant symptoms in its early stages promotes high underdiagnosis rates for the affected people. Besides pulmonary function failure, another harmful problem of COPD is the systemic effects, e.g., heart failure or voice distortion. Howeve
Actin/myosin-based gliding motility in apicomplexan parasites
Apicomplexan parasites move and actively enter host cells by substrate-dependent gliding motility, an unusual form of eukaryotic locomotion that differs fundamentally from the motility of prokaryotic and viral pathogens. Recent research has uncovered some of the cellular and molecular mechanisms underlying parasite motility, transmigration, and cell invasion during life cycle progression. The glid
Emotions of perpetrators and victim-survivors: multi-layered violence against Chinese women during the Asia-Pacific War
This essay uses a microhistory of Chinese comfort women during the Asia-Pacific War to illuminate the gendered dynamics of violence and the contrasting emotions experienced by both sexually abused women and their Japanese perpetrators, forming a perpetrator-victim dyad. The essay employs the concept of intersectional emotions within a micro-historical framework to demonstrate that this violence ag
Emotions in the making : Sexual violence in the Japanese empire, 1937–1945
This article applies the history of emotions lens to study the emotions experienced by the ‘comfort women’ in the Japanese Empire. Emotions have been a long-neglected aspect in the study of military sexual violence. The article examines how a mélange of positive and negative emotions enabled those women to exercise some limited agency in a confined and tightly regulated space and, in some rare cas