Background The growing awareness of transfusion-associated morbidity and mortality necessitates investigations into the underlying mechanisms. Small animals have been the dominant transfusion model but have associated limitations. This study aimed to develop a comprehensive large animal (ovine) model of transfusion encompassing: blood collection, processing and storage, compatibility testing right

As the work of the IWA Task Group on Benchmarking of Control Strategies for wastewater treatment plants (WWTPs) is coming to an end, it is essential to disseminate the knowledge gained. For this reason, all authors of the IWA Scientific and Technical Report on benchmarking have come together to provide their insights, highlighting areas where knowledge may still be deficient and where new opportun

Popular Abstract in Swedish Kroppens immunförsvar brukar delas in i det medfödda och det adaptiva immunförsvaret. Det medfödda immunförsvaret reagerar snabbt på yttre hot såsom bakterier. Olika sorters vita blodkroppar är väldigt viktiga för detta snabba svar på infektion och i min avhandling har jag koncentrerat mig på en av dessa; neutrofilen. Neutrofilen är den vita blodkropp som först komNeutrophil elastase (NE) has important roles in innate immunity, killing pathogens and controlling the immune response; but how NE is targeted to developing granules is not understood. Therefore, the aim of this thesis was to investigate the sorting of NE. Transfection experiments in a leukemic cell line, which were confirmed in normal hematopoietic cells, showed that a population of proNE was ta

During ascending evacuation in long stairs, there is reason to believe that factors such as physical exhaustion, human behaviour and the mental state will influence the possibility of satisfactory evacuation and affect walking speed and flow rate of people. Based on these hypotheses, a research project was initiated. As a part of the project, an initial literature study has been conducted. The lit

Objective. Between one-third and half of all radiology examinations worldwide are probably chest studies. The aim of the current study was to retrospectively evaluate the clinical influence of chest radiography. Methods. In a tertiary referral hospital, 939 consecutive daytime chest radiography examinations were evaluated. The outcome was classified as normal, incidental, or pathologic. The referr

The objective of this exploratory study was to develop signal processing methods for assisting in the diagnosis of arteriovenous fistula stenosis on patients suffering from end-stage renal disease and undergoing haemodialysis treatments. The proposed method is based on the classification of vessels sounds utilizing parameter extraction from wavelets transform coefficients. The coefficients energy

Europrise is a Network of Excellence supported by the European Commission within the 6th Framework programme from 2007 to 2012. The Network has involved over 50 institutions from 13 European countries together with 3 industrial partners and 6 African countries. The Network encompasses an integrated program of research, training, dissemination and advocacy within the field of HIV vaccines and micro

Life-history theory predicts that individuals should adjust their reproductive effort according to the expected fitness returns on investment. Because sexually selected male traits should provide honest information about male genetic or phenotypic quality, females may invest more when paired with attractive males. However, there is substantial disagreement in the literature whether such differenti

Low-dimensional, many-body systems are often characterized by ultraslow dynamics. We study a labelled particle in a generic system of identical particles with hard-core interactions in a strongly disordered environment. The disorder is manifested through intermittent motion with scale-free sticking times at the single particle level. While for a non-interacting particle we find anomalous diffusion

Environmental levels of airborne carcinogenic and related substances are comparatively better known than individual exposure and its determinants. We report on a personal monitoring program involving five Swedish urban populations. The aim of the program was to investigate personal exposure to benzene, 1,3-butadiene, formaldehyde, and nitrogen dioxide (NO2). The measurements were performed among 4

The role of inorganic pyrophosphate (PPi) as an energy carrier in the central metabolism of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus was investigated. In agreement with its annotated genome sequence, cell extracts were shown to exhibit PPi-dependent phosphofructokinase and pyruvate phosphate dikinase activity. In addition, membrane-bound pyrophosphatase activity wa

The incidence of asthma and allergy has increased throughout the developed world over the past decades. During the same period of time, the use of industrial chemicals such as phthalates, commonly used as plasticizers in polyvinylchloride (PVC) flooring material, has increased. The aim of this study was to investigate whether PVC flooring in the home of children in the age of 1-5years is associate

Caveolae are membrane organelles that play roles in glucose and lipid metabolism and in vascular function. Formation of caveolae requires caveolins and cavins. The make-up of caveolae and their density is considered to reflect cell-specific transcriptional control mechanisms for caveolins and cavins, but knowledge regarding regulation of caveolae genes is incomplete. Myocardin (MYOCD) and its rela

We present a network of sites across Fennoscandia for optical sampling of vegetation properties relevant for phenology monitoring and satellite data calibration. The network currently consists of five sites, distributed along an N-S gradient through Sweden and Finland. Two sites are located in coniferous forests, one in a deciduous forest, and two on peatland. The instrumentation consists of dual-

This paper explores strategic change communication, framed by the idea that managers can be viewed as rhetoricians. The purpose of this paper is to present and discuss senior managers’ subjective experiences of rhetorical aspects of change management. The paper draws on a case study from ABB Sweden (a power and automation technology company). In-depth interviews with senior managers, with vast ex

The increased availability of digital spatial data combined with improved capabilities of Geographic Information Systems (GIS) have allowed for the development of several global population distribution databases, such as the GPW, and LandScan. Making population distribution data available as a high-resolution raster database which facilitates rapid GIS analysis at the local level and for any zo

Very high levels of ambient particulate matter (PM) are frequently encountered in the north of Italy and air quality limits are regularly exceeded. To obtain quantitative information on the pollution sources and to gain understanding of the dynamics of pollution episodes in this populated area PM10 and/or PM2.5 samples were collected daily at nine urban to regional sites distributed over the centr

The vicicitudes of today's global economy and increasing awareness of employee well-being call for relevance of psychological capital. The study set out to review and explore the importance of psychological capital and has suggested a double-loop framework to explain the mechanisms of psychological capital.