Sökresultat

Filtyp

Din sökning på "*" gav 531342 sökträffar

Phase Reassignment with Efficient Estimation of Phase Difference

The recently developed Matched Phase Reassignment (MPR) gives a time-frequency local measure of phase difference between short oscillatory transient signals. However, the resulting phase estimate is not satisfactory as it has poor resolution for high oscillatory frequencies. The MPR is also sensitive to high noise levels and is computationally cumbersome. In this paper, a novel reassignment method

Sensor node calibration in presence of a dominant reflective plane

Recent advances in simultaneous estimation of both receiver and sender positions in ad-hoc sensor networks have made it possible to automatically calibrate node positions - a prerequisite for many applications. In man-made environments there are often large planar reflective surfaces that give significant reverberations. In this paper, we study geometric problems of receiver-sender node calibratio

ROBUST PHASE DIFFERENCE ESTIMATION OF TRANSIENTS IN HIGH NOISE LEVELS

This paper presents the Reassignment Vector Phase Difference Estimator (RVPDE), which gives noise robust relative phase estimates of oscillating transient signals in high noise levels. Estimation of relative phase information between signals is of interest for direction of arrival estimation, source separation and spatio-temporal decoding in neurology as well as for soundscape analysis. The RVPDE

WONCA Europe position statement on the redefinition of fatty liver disease

Family doctors and general practitioners (GPs) are the frontline in the management of fatty liver disease. With its high prevalence and strong association with other conditions commonly treated in primary care, the voice of family doctors and GPs has an important role in informing the discussion on the redefinition of fatty liver disease. Primary care uptake of any proposed name will be hampered i

Evaluation of the degradation of desamino1,D-arginine8-vasopressin by nasal mucosa.

The nasal route is a convenient and simple way to administer peptides to humans. Absorption of the drug, however, requires passage of the substance through the nasal mucosa. This is a possible site of enzymatic degradation of the peptide. It is shown that rabbit nasal mucosa homogenates rapidly degrade the synthetic anti-diuretic hormone analogue desamino1,D-arginine8-vasopressin in vitro. The met

Pharmacokinetic and pharmacologic properties of antiuterotonic oxytocin analogs in the rat

The pharmacologic and pharmacokinetic properties were evaluated in a series of antiuterotonic oxytocin analogs, modified at positions 1, 2, 4, 8 and, in one case, position 9 of the oxytocin (OT) molecule. [Mpa1,D-Tyr2(Et),Val4,Orn8,desGly9]-OT, [Mpa1,Tyr2(Et),Val4,Orn8]-OT and [Mpa1,D-Tyr2,Val4,Orn8]-OT displayed similar plasma clearance rates (Clps) using the constant infusion method in rats. Two

PAM50 subtyping and ROR score add long-term prognostic information in premenopausal breast cancer patients

PAM50 intrinsic subtyping and risk of recurrence (ROR) score are approved for risk profiling in postmenopausal women. We aimed to examine their long-term prognostic value in terms of breast cancer-free interval (BCFi) and overall survival (OS) (n = 437) in premenopausal women randomised to 2 years of tamoxifen versus no systemic treatment irrespective of hormone-receptor status. Intrinsic subtypin

Revealing the sensing mechanism of a fluorescent pH probe based on a bichromophore approach

Fluorescence sensing plays an increasingly important role in biology and biomedicine. For many practical applications of fluorescent probes, an “off-on” response is preferred. The question of how fluorescence quenching/enhancement occurs is fundamental and of high importance for application and design of new fluorescent probes. The sensing mechanism of an aminorhodamine (TMARh) pH probe is investi

Wardens of Civilisation : The Political Ecology of Australian Far-Right Civilisationism

The notion of a superior “civilisation” has been a hallmark of the politics of Western institutions and fringe white supremacists alike. Known ideologically as “civilisationism”, it has occupied a prominent position in the ideology of the Australian far-right. Paying tribute to their settler-colonial origins, the far-right has consistently promoted “white civilisation”, even inspiring terrorist at

Genetics and Epigenetics of Manganese Toxicity

Purpose of Review: At elevated levels, the essential element manganese (Mn) is neurotoxic and increasing evidence indicates that environmental Mn exposure early in life negatively affects neurodevelopment. In this review, we describe how underlying genetics may confer susceptibility to elevated Mn concentrations and how the epigenetic effects of Mn may explain the association between Mn exposure e

Hot-Wall MOCVD for High-Quality Homoepitaxy of GaN : Understanding Nucleation and Design of Growth Strategies

Thick GaN layers with a low concentration of defects are the key to enable next-generation vertical power electronic devices. Here, we explore hot-wall metalorganic chemical vapor deposition (MOCVD) for the development of GaN homoepitaxy. We propose a new approach to grow high-quality homoepitaxial GaN in N2-rich carrier gas and at a higher supersaturation as compared to heteroepitaxy. We develop

Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men

There is substantial genetic predisposition to bladder cancer (BC). Recently, blood pressure (BP) was positively associated with BC risk in men, but the potential interaction with genetic susceptibility for BC is unknown. We investigated a weighted genetic risk score (wGRS) of 18 BC genetic variants, BP, and their interaction, in relation to incident urothelial cancer (UC, n = 385) risk in 10,576

Practicing What We Preach? Reflections on More Sustainable and Responsible IS Research and Teaching Practices

Research on IS solutions for environmental sustainability have evolved to a modest, but firm body of knowledge. Despite this progressive understanding about the potential of IS in enabling environmental sustainability, our academic practices seem widely unaffected by these insights. The way we do research or conduct teaching is rarely influenced by sustainability considerations. For example, befor