PurposeSelenium has been suggested to be protective against breast cancer, but the evidence remains inconclusive. Hence, it is important to further examine the potential protective effect. This prospective cohort study investigates pre-diagnostic selenium intake in relation to breast cancer risk. In addition, we analyze serum selenium as a marker of dietary intake.MethodsThis study includes 17,035

Insulin resistance and lower muscle quality (strength divided by mass) are hallmarks of type 2 diabetes (T2D). Here, we explore whether alterations in muscle stem cells (myoblasts) from individuals with T2D contribute to these phenotypes. We identify VPS39 as an important regulator of myoblast differentiation and muscle glucose uptake, and VPS39 is downregulated in myoblasts and myotubes from indi

Liquid chromatography-mass spectrometry (LC-MS) and mass spectrometry imaging (MSI) are two techniques that are routinely used to study proteins, peptides, and metabolites at a large scale. Thousands of biological compounds can be identified and quantified in a single experiment with LC-MS, but many studies fail to convert this data to a better understanding of disease biology. One of the primary

The building industry demands ever more effective structural elements with a multitude of requirements at the same time. There is increasing interest for load-bearing glass elements which can be deployed in timber structures, e.g. in the outer façade or as column or beam elements within the building. In an on-going research project, the materials glass, timber and the adhesive combining the former

Endogenous and synthetic cannabinoids exert antiproliferative and proapoptotic effects in various types of cancer and in mantle cell lymphoma (MCL). In this study, we evaluated the expression of cannabinoid receptors type 1 and type 2 (CB1 and CB2) in non-Hodgkin lymphomas of B cell type (n = 62). A majority of the lymphomas expressed higher mRNA levels of CB1 and/or CB2 as compared to reactive ly

Purpose – The aim of this paper is to contribute with increased knowledge of the complex role of internal communication during a crisis like the COVID-19 pandemic. More specifically, the authors want to address the following research questions. How can the overall approach to internal crisis communication during the pandemic be interpreted, and what view of internal crisis communication does this

In this paper I present two normative standpoints that have been used to de ne and evaluate human decision making: ’economic man’ and ’ecological rationality’. I argue that both norms are unsuitable to understand decision making in a natural environment. I do so by trying to apply them to a real-life decision situation; that of buying pasta in a Swedish supermarket. Neither account is su ciently f

Inom byggsektorn måste byggnader vara mer energieffektiva än någonsin tidigare. Tuffare byggregler kräver allt mer exakta energibehovsberäkningar för att säkerställa byggnadens operativa prestanda. Överföringsvärmeöverföringsförluster genom byggnadens kuvert spelar en nyckelroll i byggnadens totala energiprestanda. Att underskatta dessa förluster kan leda till att energikraven inte uppfylls. För nWithin the construction sector buildings are required to be more energy efficient than ever before. Tougher building regulations require ever more accurate energy demand calculations to ensure a building’s operational performance. Transmission heat transfer losses through a building’s envelope play a key role in the overall energy performance of the building. Underestimating these losses may lead

Solid organ transplant (SOT) recipients run a high risk for adverse outcomes from COVID-19, with reported mortality around 19%. We retrospectively reviewed all known Swedish SOT recipients with RT-PCR confirmed COVID-19 between March 1 and November 20, 2020 and analyzed patient characteristics, management, and outcome. We identified 230 patients with a median age of 54.0 years (13.2), who were pre

This thesis takes an interest in newer forms of contract-based dispute resolution used in commercial disputes. Public civil trial and arbitration has for a long time been the procedure of choice for disputing commercial parties. Arbitration is still by far the most established and used procedure when it comes to private dispute resolution. However, for some decades, newer forms of private procedurThis thesis takes an interest in newer forms of contract-based dispute resolution used in commercial disputes. Public civil trial and arbitration has for a long time been the procedure of choice for disputing commercial parties. Arbitration is still by far the most established and used procedure when it comes to private dispute resolution. However, for some decades, newer forms of private procedur