Introduction The provision of healthcare for patients with inflammatory arthritis occurs in the context of somewhat conflicting targets, values and drivers. Therefore, there is a need for introducing 'value-based healthcare' defined as the value of patient relevant health outcomes in relation to costs. This term is a central part of tomorrow's healthcare sector, especially for rheumatic diseases,

Blastocystis is an enteric protozoan purportedly associated with numerous clinical cases of diarrhea, flatulence, vomiting, and other gastrointestinal symptoms. Despite new knowledge of Blastocystis cell biology, genetic diversity, and epidemiology, its pathogenic potential remains controversial. Numerous clinical and epidemiological studies either implicate or exonerate the parasite as a cause of

Background. Knowledge on the globally outstanding Amazonian biodiversity and its environmental determinants stems almost exclusively from aboveground organisms, notably plants. In contrast, the environmental factors and habitat preferences that drive diversity patterns for micro-organisms in the ground remain elusive, despite the fact that micro-organisms constitute the overwhelming majority of li

Company cars have received considerable attention because of their partial tax-exemption and the changes in travel behaviour they stimulate, including car model choices, distances driven, and car ownership patterns. This paper is the first to present evidence on actual transport behaviour change, based on mobility and fuel diaries, and comparing a sample of 624 company cars and 9328 private cars i

The longevity of timber structures in exposed outdoor environments is often perceived to be unreliable as compared with that of concrete and steel structures. This situation is exacerbated to some extent by the fact that the European commission for standardization (CEN) currently provides no quantitative method for service life assessment of timber structures. To counteract this, the present thesi

En historisk introduktion till erotiska bildmotiv i konsten och i grafiskt tryck, i europeiska privatsamlingar och museer från 1500-talet.

There are more child refugees in Europe than at any point since the end of the Second World War (Save the Children 2016). This is affecting both communities on the move and communities where uprooted people are resettling. A humanitarian problem on this scale demands a socially just response. For young refugees, education is a fundamental means of integrating into their new context and the act

Objectives/Hypothesis: Postoperative tinnitus and taste disturbances after myringoplasty are more common than previously reported. Study Design: This study was a retrospective analysis of prospectively collected data from the Swedish National Quality Registry for Myringoplasty. Methods: The analysis was performed on extracted data from all counties in Sweden collected from database A from 2002 to

Ordet κλώταξ är känt från en enda bevarad antik grekisk text, Kosmas Indikopleustes’ Topographia Christiana, där det förekommer sammanlagt fyra gånger. Översättare och lexikografer har haft besvär med ordet. Detta är ett försök att närmare precisera dess betydelse samt att göra det troligt att κλώταξ är synonymt med det något vanligare κνώδαξ.

We analyze thoroughly the statistical properties of the 1- spectrum in energy interval 9.5-18.5 MeV for Hg206, Pb204,206,208, and Po210 nuclei. To this aim we use the Skyrme interaction SLy4 and the volume pairing interaction, treated in the BCS approximation, as our model Hamiltonian to create a single-particle spectrum and to analyze excited states. The excited states are obtained in the quasipa

Non-coding RNAs regulate many biological processes including neurogenesis. The brain-enriched miR-124 has been assigned as a key player of neuronal differentiation via its complex but little understood regulation of thousands of annotated targets. To systematically chart its regulatory functions, we used CRISPR/Cas9 gene editing to disrupt all six miR-124 alleles in human induced pluripotent stem

Objective- Revealing patterns of associations between circulating protein and lipid levels could improve biological understanding of cardiovascular disease (CVD). In this study, we investigated the associations between proteins related to CVD and triglyceride (TG), total cholesterol, LDL (low-density lipoprotein), and HDL (high-density lipoprotein) cholesterol levels in individuals from the genera

BACKGROUND: Different mechanical ventilation settings are known to affect lung preservation for lung transplantation. Measurement of particle flow in exhaled air may allow online assessment of the impact of ventilation before changes in the tissue can be observed. We hypothesized that by analyzing the particle flow, we could understand the impact of different ventilation parameters.METHODS: Partic