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The last several years of research, including children followed from birth and extensive genetic studies, have resulted in a paradigm shift of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Autoimmune T1DM is characterized by the appearance in early childhood of a first β-cell autoantibody against either insulin (IAA) or GAD65 (GADA), or both. The genetic etiology is strongly as
Despite the numerous cultural networks within and outside of European contexts of culture-led urban development as well as transnational cultural policy-making, in-depth analyses of such networks remain scarce. In light of this, the article introduces the network Trans Europe Halles (TEH, est. 1983) as an empirical case study that illustrates cultural grassroots organising across its 165+ members
This article explores the development process of a sharing platform in the tourism industry, drawing on a longitudinal case study of a sharing-based business in adventure tourism in Sweden. The purpose is to explore how sharing business models emerge through processes of ideological narration—the strategic use of stories to shape and sustain a business. Over a two-year period, empirical data were
We address two research applications in this methodological review: starting from an audio recording, the goal may be to characterize nonlinear phenomena (NLP) at the level of voice production or to test their perceptual effects on listeners. A crucial prerequisite for this work is the ability to detect NLP in acoustic signals, which can then be correlated with biologically relevant information ab
Nonlinear phenomena (NLP) are often associated with high arousal and function to grab attention and/or signal urgency in vocalizations such as distress calls. Although biomechanical models and in vivo/ex vivo experiments suggest that their occurrence reflects the destabilization of vocal fold vibration under intense subglottal pressure and muscle tension, comprehensive descriptions of the dynamics
At some point in our evolutionary history, humans lost vocal membranes and air sacs, representing an unexpected simplification of the vocal apparatus relative to other great apes. One hypothesis is that these simplifications represent anatomical adaptations for speech because a simpler larynx provides a suitably stable and tonal vocal source with fewer nonlinear vocal phenomena (NLP). The key assu
Nonlinear phenomena (NLP) are acoustic irregularities that are widespread in animal and human vocal repertoires, as well as in music. These phenomena have recently attracted considerable interest but, surprisingly, have never been the subject of a comprehensive review. NLP result from irregular sound production, contribute to perceptual harshness, and have long been considered nonadaptive vocal fe
This paper aims to identify micro-level processes shaping the narratives surrounding regional opportunity spaces. A process perspective is applied to examine how place leaders engage in shaping narratives to influence the perception of opportunity spaces. The empirical research is based on a comparative case study of four peripheral regions in Germany, comprising 92 interviews with regional stakeh
Regional diversification has been positioned as a topic of great interest among researchers of economic geography, however, there remain some research gaps that must be attended to. Through the use of complex networks analysis from this literature in a period from 1975 to 2022, we identify some methodological and theoretical issues related to its measurement methods, the lack of an integrative fra
Understanding the “fit” of models designed to predict binary outcomes has been a longstanding problem across the social sciences. We propose a flexible, portable, and intuitive metric for quantifying the change in accuracy between two predictive systems in the case of a binary outcome: the InterModel Vigorish (IMV). The IMV is based on an analogy to weighted coins, well-characterized physical syst
Innovation plays a crucial role in shaping technological, economic, and social progress in modern societies. In the realm of bridge integrity management, the development and diffusion of technologies to acquire information can significantly enhance industries' safety and functionality capabilities. Among the most widely diffused bridge types in Europe and North America, Gerber bridges are particul
In this article, I examine and compare how the book of Esther is interpreted on two Swedish and one US based online discussion forums (Familjeliv, Flashback, and Reddit). The study is conducted from a reception critical perspective, highlighting dominant interpretations and their ideological consequences, such as the reproduction of relations of domination. While religious actors tend to praise Es
Fragmented micro- and nanoplastics are widespread pollutants with adverse effects on the environment. However, the breakdown process does not end with micro- and nanoplastics but is expected to continue until carbon dioxide has been formed. During this process the plastics will undergo chemical changes and small molecules may be released. We have broken down small amine-modified (∅53 nm) and carbo
Organ donation is a crucial aspect of healthcare, yet, the number of donors is insufficient to cover the demand for transplant procedures. In the European Union, around 15 people die each day waiting for a life-saving organ. National policies differ greatly among countries, but it is unclear how successful policies affect Deceased Organ Donation when introduced in other settings. This paper explor
We introduce the special issue, ‘Trust in and through Academic Development’, which includes papers and reflections written by 26 authors from seven different countries. These collected papers demonstrate that trust-building is an integral part of academic developers’ practice, serving as an anchor in uncertain and turbulent times. Based on the research presented in this issue and elsewhere, we def
This thesis examines the immersive experiences of players in video game worlds, focusing onThe Legend of Zelda: Breath of the Wild and Super Mario Odyssey. Drawing on art historicalconcepts such as perception, reception and perspective in academic painting, as well asphenomenological insights into embodied perception and atmospheres, the study explores howvisual design, game mechanics and narrativThis thesis examines the immersive experiences of players in video game worlds, focusing on The Legend of Zelda: Breath of the Wild and Super Mario Odyssey. Drawing on art historical concepts such as perception, reception and perspective in academic painting, as well as phenomenological insights into embodied perception and atmospheres, the study explores how visual design, game mechanics and narr
A virtually complete and articulated plesiosaur skeleton (MH 7) is described from the Lower Jurassic (Toarcian) Posidonienschiefer Formation near Holzmaden in southern Germany. Plesiosaur remains are rare in this rock unit compared to those of other marine reptiles, such as ichthyosaurs and thalattosuchian crocodylomorphs. The new specimen offers an opportunity to assess the biodiversity of Early
