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Public libraries as promoters of social sustainability?

Introduction. The aim of this paper is to critically examine how public libraries are portrayed as contributing to social sustainability. Meanings ascribed to the concept are investigated and if, and then how, the public library is shaped in relation to it.Method. Library plans from five municipalities in Sweden are analysed and discussed in the light of previous research. Analysis. Bacchi’s metho

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

Overcoming cellular growth restriction, including the evasion of cellular senescence, is a hallmark of cancer. We report that PAK4 is overexpressed in all human breast cancer subtypes and associated with poor patient outcome. In mice, MMTV-PAK4 overexpression promotes spontaneous mammary cancer, while PAK4 gene depletion delays MMTV-PyMT driven tumors. Importantly, PAK4 prevents senescence-like gr

Blue-green stormwater systems for citywide flood mitigation : Monitoring, conceptualization, modeling, and evaluation

Considering the growth in urbanization, leading to an increase in impervious surfaces, and the changing climate, enhancing the intensity and frequency of rainfall events, existing urban drainage networks—separate or combined sewer systems—are presumed to face substantially elevated hydraulic loads, causing pluvial floods in urban areas. There are several ways to address these challenges. Cities ca

Modelling radiation damage to pixel sensors in the ATLAS detector

Silicon pixel detectors are at the core of the current and planned upgrade of the ATLAS experiment at the LHC. Given their close proximity to the interaction point, these detectors will be exposed to an unprecedented amount of radiation over their lifetime. The current pixel detector will receive damage from non-ionizing radiation in excess of 1015 1 MeV neq/cm2, while the pixel detector designed

Population-based, nationwide registration of prostatectomies in Sweden

Introduction: Radical prostatectomy (RP) is a common surgical procedure with a risk of postoperative erectile dysfunction and urinary incontinence. There is a need for data on RP as a basis for quality assurance and benchmarking. Methods: In 2015, prostatectomies in Sweden (PiS) form was implemented in the National Prostate Cancer Register (NPCR) of Sweden with data on pre-, peri- and post-operati

Assessing residual renal function and efficiency of hemodialysis - an application for urographic contrast media

Background: In patients on hemodialysis with end-stage renal disease there is an increasing interest in measuring both residual renal function (RRF) and quantity and quality of dialysis because insufficient dialysis gives higher mortality. For that purpose we have measured clearances of two urographic iodine (I) contrast media (CM) with different molecular masses (iohexol 821 u and iodixanol 1,550

Low risk of contrast-medium-induced nephropathy with modern angiographic technique

Objective and design. A retrospective study of the incidence of contrast‐medium‐induced nephropathy (CMN) in patients with renal insufficiency.Subjects. All angiographies with and without endovascular therapeutic procedures (n=2400) performed at the hospital during 1 year were evaluated. A total of 139 patients were found to have a preangiographic serum‐creatinine (s‐Cr) of 150 μmol L–1 or above.

Search for diboson resonances in hadronic final states in 139 fb−1 of pp collisions at √s = 13 TeV with the ATLAS detector

Narrow resonances decaying into W W, W Z or ZZ boson pairs are searched for in 139 fb−1 of proton-proton collision data at a centre-of-mass energy of s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider from 2015 to 2018. The diboson system is reconstructed using pairs of high transverse momentum, large-radius jets. These jets are built from a combination of calorimeter- and tr

Nationell styrning behövs för at förebygga översvämningar och vattenbrist

DebattTillgången till vatten kan inte längre ses som en lokal fråga utan måste ses ur ett bredare perspektiv, som kräver en samordning som är ny för Sverige. Det behövs sammanhängande nationell styrning och en strategi med helhetssyn på vattenfrågan, skriver nio svenska vattenexperter som kommer att debattera detta ämne under politikerveckan i Almedalen.

Next-Generation Sequencing of 17 Genes Associated with Venous Thromboembolism Reveals a Deficit of Non-Synonymous Variants in Procoagulant Genes

BACKGROUND: The heritability of venous thromboembolism (VTE) is only partially explained by variants in 17 previously VTE-associated genes.OBJECTIVE: This article screens for additional rare variants in the 17 genes and investigates the relative contributions of pro- and anticoagulant genes to VTE.PATIENTS AND METHODS: Ninety-six VTE patients from the population-based Malmö Thrombophilia Study wer

Combustion characteristics of gasoline DICI engine in the transition from HCCI to PPC : Experiment and numerical analysis

Both numerical simulations and experiments were conducted in a heavy-duty DICI engine, with PRF81 as a gasoline surrogate, to investigate how the fuel stratification, auto-ignition and combustion are affected by the start of injection (SOI). The intake air temperature was adjusted to keep the combustion phasing constant when the SOI was swept from −100 to −20 oCA ATDC, covering different regimes o

Open Collaborative Data: a pre-study on an emerging practice

Data intense defined software is becoming more and more prevalent, especially with the advent of machine learning and artificial intelligence. With data intense systems comes both challenges – to continue to collect and maintain quality – and opportunities – open innovation by sharing with others.To understand challenges and opportunities with ODC, we ran 5 focus groups (4 in Lund and 1 in Kista)

Platelet Indices and Risk of Death and Cardiovascular Events : Results from a Large Population-Based Cohort Study

Studies evaluating the relationship between platelet indices and cardiovascular (CV) outcomes yielded conflicting results. We assessed the incidence of adverse events according to baseline quintiles of platelet indices in the prospective cohort of the Malmö Diet and Cancer Study. A total of 30,314 individuals (age 57 ± 8 years) were followed for a median of 16 years (468,490 person-years). Outcome

Multicenter study on postcardiotomy venoarterial extracorporeal membrane oxygenation

Objectives: The aim of this study was to identify the risk factors associated with early mortality after postcardiotomy venoarterial extracorporeal membrane oxygenation. Methods: This is an analysis of the postcardiotomy extracorporeal membrane oxygenation registry, a retrospective multicenter cohort study including 781 patients aged more than 18 years who required venoarterial extracorporeal memb