OBJECTIVES: Clinical presentation of primary Sjögren's syndrome (pSS) varies considerably. A shortage of evidence-based objective markers hinders efficient drug development and most clinical trials have failed to reach primary endpoints.METHODS: We performed a multicentre study to identify patient subgroups based on clinical, immunological and genetic features. Targeted DNA sequencing of 1853 auto

This article explored the use of social media and mobile communication by women in Saudi Arabia who campaigned for the right to drive from 1990. Due to the globally unique ban on women driving in the Kingdom, females always needed a male driver to transport them. The Saudi government announced in September 2017 that women would be allowed to drive from June 2018. Using the theory of connective act

This article is concerned with the visual culture of global health data using antimicrobial resistance (AMR) as an example. I explore how public health data and knowledge are repackaged into visualisations and presented in four contemporary genres: the animation, the TED Talk, the documentary and the satire programme. I focus on how different actors describe a world in which there are no or few an

Atmospheric particulate matter and dust from agricultural land significantly affect air quality and human health in nearby residential areas. To quantify these air pollutants, it is important to estimate the vertical atmospheric particulate matter PM2.5, PM10, and dust flux using observations and validated models. To the authors´ knowledge, this has previously not been performed for semi-humid agr

This paper examines social class differences in fertility, using longitudinal micro-level data for a regionalsample in Sweden, 1922–2015. Using discrete-time event history models, we estimated the associationbetween social class and parity-specific duration to next birth, adjusting for household income in separatemodels. Social class was associated with fertility quite independently from income an

Modern subtractive and additive manufacturing techniques present new avenues for X-ray optics with complex shapes and patterns. Refractive phase plates acting as glasses for X-ray optics have been fabricated, and spherical aberration in refractive X-ray lenses made from beryllium has been successfully corrected. A diamond phase plate made by femtosecond laser ablation was found to improve the Stre

Human activity is a major driver of change and has contributed to many of the challenges we face today. Detailed information about human population distribution is fundamental and use of freely available, high-resolution, gridded datasets on global population as a source of such information is increasing. However, there is little research to guide users in dataset choice. This study evaluates five

Grazing can have considerable ecological impacts when managed inappropriately, however livestock production is a significant contributor to global food security and the removal of land from production is not always a viable option. Grazing management practices that incorporate periods of planned rest (i.e. strategic-rest grazing) may be an alternative to grazing exclusion or continuous grazing tha

Platform ecosystems include complementary product markets that are creating unprecedented business oppor-tunities. Competition within complementary product markets is increasingly intense and fast-changing, and this leads to increased complexity in designing strategies to gain competitive advantage. Prior literature has exten-sively analyzed the key drivers of platform adoption by end users. Recen

BACKGROUND: Climate change is set to exacerbate occupational heat strain, the combined effect of environmental and internal heat stress on the body, threatening human health and wellbeing. Therefore, identifying effective, affordable, feasible and sustainable solutions to mitigate the negative effects on worker health and productivity, is an increasingly urgent need. OBJECTIVES: To systematically

High energy use for space conditioning in residential buildings is a significant economic factor for owners and tenants, but also contributes to resource depletion and carbon emissions due to energy generation. Many existing dwellings should thus be retrofitted in order to fulfil the ambitious EU carbon emission mitigation goals by 2050. To investigate how future climate resilience can be implemen

The existing information supports the use of this material as described in this safety assessment. Hexyl hexanoate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog hexyl isobutyrate (CAS # 2349-07-7) show that hexyl hexanoate is not

Background: Specific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but knowledge of adherence to the guidelines is lacking. The guidelines were developed to avoid unnecessary suffering from preventable conditions. The aims of the study were to investigate 1) planned health care visits in relation to the co-morbidities described in specific medic

This paper considers a detailed numerical analysis of combined liquid-gas co-flow in a gas channel, with liquid-gas counter-flow in a porous transport layer, as is typically found on the cathode side of a polymer electrolyte fuel cell. The geometry is obtained by digital reconstruction of nano-computer tomography images. From this, the domain is tessellated with an unstructured castellated or octr

Avhandlingen beskriver syntes och egenskaper hos fem stycken olika katjonledande polymersystem. Dessa system designades så att polymererna skulle kunna mikrofasseparera i distinkta faser med en fas för mekanisk styrka och en för jonledningsförmåga. Tre stycken studier inriktade på litiumjonledande polymer för batterier och två på protonledande polymermembran till bränsleceller är inkluderade i avhThis thesis describes the synthesis and properties of five different cation conducting polymer systems. These systems were designed so that the polymers would be able to microphase separate into distinct phases with one phase for mechanical strength and one for ionic conductivity. Three studies focused on lithium ion conducting polymers for batteries and two on proton exchange membranes for fuel c

An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains ten thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technologies. This sensor allows to determine maximum five different analytes nearly simultaneously by serially dividing the single microchannel in