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The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) and lung cancer represent progressive lung diseases with a poor prognosis. IPF represents a risk factor for the development of lung cancer, and the incidence of lung cancer is increased in patients with IPF. Disease pathogenesis of IPF and lung cancer involves common genetic alterations, dysregulated pathways, and the emergence of hyperplastic and metaplastic ep

Romania is a family and it needs a strict father : Conceptual metaphors at work in radical right populist discourses

Investigating Romanian radical right populism, I evidence the gendered nature of conceptual metaphors and provide insights on the specific masculinities that they underpin in such political discourses. With the 2004 presidential elections as a backdrop, the analysis focuses on how the radical right populist candidates articulated in their discourses the conceptual metaphor of the "strict father."

Antifeminist and “truly liberated” : Conservative performances of gender by women politicians in Hungary and Romania

This article employs a two-level analysis to compare the discursive performance of gender on social media in Hungary and Romania; the two countries with the lowest percentage of women in politics in the European Union (EU). First, by revealing the tension between conservative views about gender roles, and social and political specificities in the two countries, the research illustrates how various

Comparison of TDIP and SIP measurements in the field scale

The frequency-dependence of the induced polarization effect (IP), in the so-called spectral IP (SIP), has been demonstrated to be strongly correlated to important parameters in hydrogeological and environmental investigations. This has prompted the development of measuring instruments and modelling techniques towards the collection of laboratory and field data with enhanced accuracy and at a broad

Active Rehabilitation for persons with spinal cord injury in Botswana – effects of a community peer-based programme

Study design:: Prospective cohort study with a repeated measures analysis. Objectives:: To measure the effects of the Active Rehabilitation (AR) training programme for community-dwelling individuals with spinal cord injury (SCI) in Botswana on physical independence, wheelchair mobility, self-efficacy, life satisfaction, level of physical activity and community participation. Setting:: The inaugura

Is low-level HIV-1 viraemia associated with elevated levels of markers of immune activation, coagulation and cardiovascular disease?

Objectives: The clinical significance of low-level viraemia (LLV) during antiretroviral therapy (ART) is debated. We retrospectively investigated longitudinal levels of plasma markers associated with inflammation, altered coagulation and cardiovascular disease in Swedish HIV-positive adults in relation to LLV or permanent virological suppression during long-term ART. Methods: Plasma levels of C-re

Developmental tuning in a spinal nociceptive system: effects of neonatal spinalization

Recent studies indicate a modular organization of the nociceptive withdrawal reflex system. Each module has a characteristic receptive field, closely matching the withdrawal movement caused by its effector muscle. In the rat, the strength of the sensory input to each module is tuned during the first postnatal weeks, i.e., erroneous spinal connections are depressed, and adequate connections are str