It is well established that there is uneven availability of credit across space, in particular for SMEs. The evidence on whether this translates into differences in actual business investments remains scarce. We assess this question by using firm-level data for Swedish firms and estimate the extent to which the average investment-cash flow sensitivities of firms vary across the urban–rural hierarc

Cellular localization has received marked attention in academia and in industry, as indicated by a rapidly expanding volume of literature specific to vehicular environments. Impressive results have been shown for a number of problems as measured by metrics such as accuracy and latency. This article identifies five important requirements for cellular localization for safety-critical systems with a

Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the present study, we aimed to identify novel drugs that can inhibit the growth and survival of chemoresistant neuroblastoma. High-throughput screening identified a small molecule,

Background: Although effective return-to-work (RTW) interventions are not widely available for individuals with common mental disorders on sick leave, there is potential for transforming such interventions into a digital solution in an effort to make them more widely available. However, little is currently known about the viewpoints of different stakeholder groups, which are critical for successfu

Patients with traveler’s diarrhea (TD) can acquire extended-spectrum-beta-lactamase (ESBL)-producing members of the Enterobacterales (EPE) during travel to areas of endemicity. The aim of the present study was to investigate the prevalence and characteristics of EPE carriage in travelers from southern Sweden who were sampled for bacterial diagnostics of TD compared to those of EPE carriage 10 year

The development of innovative and competitive products and mastery of IT&T technologies are crucial for a company's long-term success in the global market. The main flag bearers for development are product developers, but it is questionable whether the existing systems are appropriate for the education of such professionals. For example, one study found large deficiencies concerning their skil

CO2 is a greenhouse gas that is believed to be one of the main contributors to global warming. Recent studies show that a combination of methanol as a renewable fuel and advanced combustion concepts could be a promising future solution to alleviate this problem. However, high unburned hydrocarbon (UHC) and carbon monoxide (CO) emissions can be stated as the main drawback in low load operations whe

Understanding the mechanism of action of compounds capable of inhibiting amyloid-fibril formation is critical to the development of potential therapeutics against protein-misfolding diseases. A fundamental challenge for progress is the range of possible target species and the disparate timescales involved, since the aggregating proteins are simultaneously the reactants, products, intermediates, an

Strand, S.M., H.H. Christiansen, M. Johansson, J. Åkerman, O. Humlum. 2020. Permafrost and Periglacial Processes 2020Active layer probing in northern Sweden, northeast Greenland, and central Svalbard indicates active layer thickening has occurred at Circumpolar Active Layer Monitoring (CALM) sites with long‐term, continuous observations, since the sites were established at these locations in 1978, 1996, and 2000, respectively. The study areas exhibit a reverse latitudinal gradient in average active layer thickne

PURPOSE: It has been suggested that a high intake of sugar or sweeteners may result in an unfavorable microbiota composition; however, evidence is lacking. Hence, in this exploratory epidemiological study, we aim to examine if intake of added sugar, sugar-sweetened beverages (SSBs) or artificially sweetened beverages (ASBs) associate with the gut microbiota composition.METHODS: Participants (18-70

ObjectivesMindfulness, positive self-related attitudes and secure attachment have been shown to protect against psychopathology during adolescence, but it is unknown how these factors are related to each other and which are most strongly linked to psychopathology symptoms.MethodsA cross-sectional research design was used with a large sample of adolescents (aged 14 to 18 years; n = 1660) that compl

The association between breast cancer risk defined by the Tyrer-Cuzick score (TC) and disease prognosis is not well established. Here, we investigated the relationship between 5-year TC and disease aggressiveness and then characterized underlying molecular processes. In a case-only study (n = 2474), we studied the association of TC with molecular subtypes and tumor characteristics. In a subset of

Objectives: This study evaluated if selecting the left ventricular (LV) target segment by echocardiography-derived late mechanical activation, with access to multimodality imaging for scar and venous anatomy, could help to increase responder rates to cardiac resynchronization therapy (CRT). Background: LV lead placement is important for clinical outcome, but the optimal strategy for LV lead placem

Recently a slight tension between data and predictions has been reported in tt¯ W production by both the CMS and ATLAS collaborations. We revisit the theoretical predictions for this process, focussing on the following two effects. We disentangle various effects that lead to asymmetries among the leptonic decay products of the (anti-)top quarks and W bosons, for which we find that the spin correla

A software prototype is developed for assessing and updating the reliability of single-cell prestressed concrete box girders subjected to chloride-induced reinforcement corrosion. The underlying system model consists of two integrated sub-models: a condition model for predicting the deterioration state of the box girder and a structural model for evaluating the overall system reliability. The cond