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Left-right Orientation, Homeownership and Class Position in Sweden

Sweden is a country where left-right orientation structures the political landscape, homeownership is increasingly important, and the importance of class for political preferences and behavior is changing or even weakening. This article explores the significance of homeownership for left-right orientation in Sweden, and extends the relationship to include class position. By combining detailed cros

Collection of microlevel Safety and efficiency Indicators with Automated Video Analysis

This paper revises the theoretical grounds for relation of the micro-level behaviour indicators to the safety and efficiency (level-of service) of the local traffic system. Automated video analysis is suggested as a tool for collection of the individual data about road users driving trajectories and speeds and interaction with other road users. The authors describe the current state of the video a

Lung bioengineering : advances and challenges in lung decellularization and recellularization

PURPOSE OF REVIEW: Bioengineering the lung based on its natural extracellular matrix (ECM) offers novel opportunities to overcome the shortage of donors, to reduce chronic allograft rejections, and to improve the median survival rate of transplanted patients. During the last decade, lung tissue engineering has advanced rapidly to combine scaffolds, cells, and biologically active molecules into fun

Characteristics of healthy vascular ageing in pooled population-based cohort studies : the global Metabolic syndrome and Artery REsearch Consortium

OBJECTIVE: Arterial ageing is characterized by increasing arterial stiffness as measured by pulse wave velocity (PWV). This process is enhanced in participants with early vascular ageing (EVA), but slowed in participants with healthy vascular ageing (HVA). We aimed to describe characteristics of EVA and HVA in a transcontinental study including 11 cohorts.METHODS: In all, 18 490 participants from

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

Purpose of Review: The environmental triggers of islet autoimmunity leading to type 1 diabetes (T1D) need to be elucidated to inform primary prevention. The Environmental Determinants of Diabetes in the Young (TEDDY) Study follows from birth 8676 children with T1D risk HLA-DR-DQ genotypes in the USA, Finland, Germany, and Sweden. Most study participants (89%) have no first-degree relative with T1D

Reduction in White Blood Cell, Neutrophil, and Red Blood Cell Counts Related to Sex, HLA, and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes

Islet autoantibodies (IAs) precede the clinical onset of type 1 diabetes (T1D); however, the knowledge is limited about whether the prodrome affects complete blood counts (CBCs) in 4- to 12-year-old children with increased genetic risk for T1D. This study tested whether CBCs were altered in 4- to 12-year-old children without (n = 376) or with one or several IAs against insulin, GAD65, or IA-2 (n =

Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay

The neurodegenerative Huntington's disease (HD) is caused by a polyglutamine (polyQ) amplification in the huntingtin protein (HTT). Currently there is no effective therapy available for HD; however, several efforts are directed to develop and optimize HTT-lowering methods to improve HD phenotypes. To validate these approaches, there is an immediate need for reliable, sensitive, and easily accessib

Near-Edge Soft X-ray Absorption Mass Spectrometry of Protonated Melittin

We have investigated the photoionization and photofragmentation yields of gas-phase multiply protonated melittin cations for photon energies at the K-shell absorption edges of carbon, nitrogen, and oxygen. Two similar experimental approaches were employed. In both experiments, mass selected [melittin+qH]q+ (q=2–4) ions were accumulated in radiofrequency ion traps. The trap content was exposed to i

Methodologies

Measurement of biosphere-atmosphere exchange of various greenhouse gases requires different techniques. In case of carbon dioxide, the net ecosystem exchange (NEE) is usually measured by the eddy covariance method. In the lack of these measurements in forests, the carbon dioxide uptake can be estimated by detecting changes in sequestrated carbon stocks or by using tree growth (dendrometric) measur

Inter-annual variability in the leaf area index of a boreal aspen-hazelnut forest in relation to net ecosystem production

The seasonal phenology of the leaf area index (LAI) is a major determinant of net ecosystem production in deciduous forest ecosystems. This study describes seasonal and inter-annual differences in LAI in a boreal aspen-hazelnut forest in central Saskatchewan, Canada, between 1994 and 2003, and relates the differences in LAI to annual net ecosystem production (FNEP). A robust method is developed to

Riskstratifiering vid pulmonell arteriell hyper­tension - Ger bättre behandling och prognos – högspecialiserat omhändertagande vid universitetssjukhusen krävs

Pulmonary arterial hypertension (PAH) is a progressive vascular disease, due to vasoconstriction and remodelling of pulmonary arteries. Survival has from diagnosis, if untreated, been found to be 1 to 2.8 years, depending on whether related to rheumatic disease or not. The ESC/ERS risk stratification tool provides a new approach to evaluate the clinical status of PAH patients. It supports a refine

Indole as a new sustainable aromatic unit for high quality biopolyesters

The aim of this research was to use indole as a new sustainable aromatic unit for polyesters. A series of new polyesters were synthesised by the polycondensation of an indole-based dicarboxylate and five potentially bio-based diols. The new polyesters are amorphous, have superior thermal quality, and can form clear transparent films.

Not now but later - A qualitative study of non-exercising pregnant women's views and experiences of exercise

Background: Evidence has shown that there are several physical and mental advantages of exercise during pregnancy. Despite this, the recommendations for exercise during pregnancy are poorly fulfilled. The aim of this study was to illuminate non-exercising pregnant women's views and experiences concerning exercise before and during pregnancy. Method: The study had a qualitative design with an induc

Steps Control the Dissociation of CO2 on Cu(100)

CO2 reduction reactions, which provide one route to limit the emission of this greenhouse gas, are commonly performed over Cu-based catalysts. Here, we use ambient pressure X-ray photoelectron spectroscopy together with density functional theory to obtain an atomistic understanding of the dissociative adsorption of CO2 on Cu(100). We find that the process is dominated by the presence of steps, whi

Groundwater augmentation through the site selection of floodwater spreading using a data mining approach (case study : Mashhad Plain, Iran)

It is a well-known fact that sustainable development goals are difficult to achieve without a proper water resources management strategy. This study tries to implement some state-of-the-art statistical and data mining models i.e., weights-of-evidence (WoE), boosted regression trees (BRT), and classification and regression tree (CART) to identify suitable areas for artificial recharge through flood

On the initial binary population for star cluster simulations

Colour–magnitude diagrams (CMDs) are powerful tools that might be used to infer stellar properties in globular clusters (GCs), for example, the binary fraction and their mass ratio (q) distribution. In the past few years, observations have revealed that q distributions of GC main-sequence binaries are generally flat, and a distribution characterized by a strong increase towards q ≈ 1 is not typica

Study protocol for an observational register-based study on health and risk factors in patients with hip and knee osteoarthritis

INTRODUCTION: Hip and knee osteoarthritis is a leading cause of disability worldwide. Currently, the course of deterioration in pain and physical functioning in individuals with osteoarthritis is difficult to predict. Factors such as socioeconomic status and comorbidity contribute to progression of osteoarthritis, but clear associations have not been established. There is a need for early identifi