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Podocalyxin-like protein as a predictive biomarker for benefit of neoadjuvant chemotherapy in resectable gastric and esophageal adenocarcinoma

Background: We have previously shown that podocalyxin-like protein (PODXL) is a prognostic biomarker for poor survival in gastric and esophageal adenocarcinoma treated with surgery up-front. The aim of the present study was to assess PODXL expression in tumors from patients treated with neoadjuvant ± adjuvant (i.e. preoperative with or without postoperative) chemotherapy, with regard to histopatho

Human rights; Early days or coming to an end?

The speech addresses how human rights are being challenged and to what extent we are witnessing the end times of human rights. Neo-liberalism and populism coming from different corners converge and contribute to the erosion of human rights as well as rule of law institutions. Attempts to link human rights to one or the other economic theory contribute to lifting human rights away from their status

Cardiovascular Risk Factors Among Older Adults With Long-Term Spinal Cord Injury

BACKGROUND: Individuals with spinal cord injury (SCI) now live longer, which increases the risk of cardiovascular disease. Knowledge of cardiovascular risk factors amenable to intervention are therefore needed to support their healthy aging. OBJECTIVE: To describe the occurrence of cardiovascular risk factors among older adults with long-term SCI and investigate the association with sociodemograph

Darriwilian (Middle Ordovician) chemostratigraphy linked to graptolite, conodont and trilobite biostratigraphy in the Fågelsång-3 drill core, Scania, Sweden

A recent core drilling in the geologically classical Fågelsång area resulted in a 58.70-m-long drill core through the lowermost Sandbian Sularp Shale, the Darriwilian Almelund Shale and Komstad Limestone, and part of the late Tremadocian to earliest Darriwilian Tøyen Shale. The shales contain zone index graptolites that are used for an update of the standard Darriwilian graptolite zone succession

PalCom MIST: a Metaprotocol for Internet Systems of Things

Future applications of internet of things (IoT) will go far beyond connecting sensors to the internet. The real challenge lies in how to easily build well working systems of things: well integrated distributed applications that support users, yet built from a variety of devices running on a variety of networks and protocols, and including services that were not designed to interoperate.Based on ou

Macro- and microvascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclerosis and vascular dysfunction in diabetes.

Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. Previous work fro

High prevalence of undiagnosed COPD among patients evaluated for suspected myocardial ischaemia

Objective: Chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) are leading causes of global morbidity and mortality. Despite the well-known comorbidity between COPD and CAD, the presence of COPD may be overlooked in patients undergoing coronary evaluation. We aimed to assess the prevalence of undiagnosed COPD among outpatients evaluated due to suspected myocardial ischem

Physical and virtual spaces among the Palestinian diaspora in Malmö

Through the construction of a Palestinian diasporic topography of Malmö, this chapter focuses on the interrelationship of multiple spaces of action and interaction of Palestinians, locally and transnationally. In addition, given the different identifications and migration trajectories of Malmö Palestinians (originating in the West Bank, Gaza but also Syria, Lebanon, Jordan, and beyond, as well as

The Angantyr model for heavy-ion collisions in Pythia8

We present a new model for building up complete exclusive hadronic final states in high energy nucleus collisions. It is a direct extrapolation of high energy pp collisions (as described by Pythia), and thus bridges a large part of the existing gap between heavy ion and high energy physics phenomenology. The model is inspired by the old Fritiof model and the notion of wounded nucleons. Two essenti

Measurements of differential cross sections of top quark pair production in association with jets in pp collisions at √s=13 TeV using the ATLAS detector

Measurements of differential cross sections of top quark pair production in association with jets by the ATLAS experiment at the LHC are presented. The measurements are performed as functions of the top quark transverse momentum, the transverse momentum of the top quark-antitop quark system and the out-of-plane transverse momentum using data from pp collisions at s=13 TeV collected by the ATLAS de

FADD (Fas-Associated Protein With Death Domain), Caspase-3, and Caspase-8 and Incidence of Ischemic Stroke

Background and Purpose- Apoptosis has been implicated in atherosclerosis and plaque rupture. This population-based study examined the relationship between 3 markers of apoptosis, that is, FADD (Fas-associated protein with death domain), caspase-3, and caspase-8, and incidence of ischemic stroke. Methods- The study population included 4356 participants from the MDCS (Malmö Diet and Cancer Study) ca

What Jimmie Got Right: Anthropologists and Sverigedemokratarna

In light of the recent Swedish elections where Sverigedemokratarna received 18% of the vote. Since the Swedish Democrats talk so much about culture, we anthropologists need to take a more nuanced position on how the issue of culture and immigrants 'fitting in' to Swedish society is discussed.

Benefit From Reperfusion With Primary Percutaneous Coronary Intervention Beyond 12 Hours of Symptom Duration in Patients With ST-Segment-Elevation Myocardial Infarction

BACKGROUND: Guidelines recommend primary percutaneous coronary intervention (PCI) in patients with ST-segment-elevation myocardial infarction (STEMI) presenting ≥12 hours of symptom onset in the presence of ongoing ischemia. However, data supporting this recommendation are limited. We evaluated the effect of primary PCI on reperfusion success, using cardiac magnetic resonance, in STEMI patients wi

National Innovation System Construction Process in Rwanda in an East African Region Context

The National Innovation System (NIS) is an interactive model of innovation that has the potential of better enhancing the use of knowledge for economic development. This approach is increasingly capturing the attention of developing economies as a means of utilizing knowledge for economic growth. This paper assesses how the NIS concept is being embraced in the East African (EA) region. It does so

Reacting boundary layers in a homogeneous charge compression ignition (HCCI) engine

An experimental and computational study of the near-wall combustion in a Homogeneous Charge Compression Ignition (HCCI) engine has been conducted by applying laser based diagnostic techniques in combination with numerical modeling. Our major intent was to characterize the combustion in the velocity- and thermal boundary layers. The progress of the combustion was studied by using fuel tracer LIF, tAn experimental and computational study of the near-wall combustion in a Homogeneous Charge Compression Ignition (HCCI) engine has been conducted by applying laser based diagnostic techniques in combination with numerical modeling. Our major intent was to characterize the combustion in the velocity- and thermal boundary layers. The progress of the combustion was studied by using fuel tracer LIF, t