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BACKGROUND: Copy number (CN) variation (CNV) of the salivary amylase gene (AMY1) influences the ability to digest starch and may influence glucose homeostasis, obesity and gut microbiota composition. Hence, the aim was to examine the association of AMY1 CNV with fasting glucose, BMI, and gut microbiota composition considering habitual starch intake and to investigate the effect of AMY1 CNV on the

The Ordovician (∼487 to 443 Ma) ended with the formation of extensive Southern Hemisphere ice sheets, known as the Hirnantian glaciation, and the second largest mass extinction in Earth History. It was followed by the Silurian (∼443 to 419 Ma), one of the most climatically unstable periods of the Phanerozoic as evidenced by several large scale (>5‰) carbon isotope (δ13C) perturbations associated w

Studies have shown that computer-based training in eating and nutrition for hospital nursing staff increased the likelihood that patients at risk of undernutrition would receive nutritional interventions. This article seeks to provide understanding from the perspective of nursing staff of conceptually important areas for computer-based nutritional training, and their relative importance to nutriti

A user-friendly high-resolution intermediate complexity dynamic and spatially distributed flow model is crucial in urban flood modeling. Planners and consultants need to improve the accuracy of floods and estimation of risks. A new flow model will serve as a rapid tool to improve identification of these. This article provides a detailed explanation of a model based on a multiple flow algorithm. MoA user-friendly high-resolution intermediate complexity dynamic and spatially distributed flow model is crucial in urban flood modeling. Planners and consultants need to improve the accuracy of floods and estimation of risks. A new flow model will serve as a rapid tool to improve identification of these. This article provides a detailed explanation of a model based on a multiple flow algorithm. Mo

Purpose: This study aims to investigate how sustainability has been incorporated – or mainstreamed - in a school at one university through techniques of responsibilization and accountabilization. Design/methodology/approach: Inspired by the extended case study methodology, the authors participated, observed and analyzed two audit-inspired processes, whose aims included ensuring that sustainability

BACKGROUND: Patient-reported outcome measures (PROMs) are validated questionnaires that are completed by patients. Arthroplasty registries vary in PROM collection and use. Current information about registry collection and use of PROMs is important to help improve methods of PROM data analysis, reporting, comparison, and use toward improving clinical practice. QUESTIONS/PURPOSES: To characterize PR

Background: To explore the determinants of incident hypertension, and especially the impact of baseline blood pressure categories, in a representative Swedish population. Methods: A 10-year longitudinal study of residents aged 30–74. Blood pressures were measured and categorized according to ESH guidelines with optimal blood pressure < 120/80 mmHg, normal 120–129/80–84 mmHg, and high normal 130–13

Urinary extracellular vesicles (uEV) are a topical source of non-invasive biomarkers for health and diseases of the urogenital system. However, several challenges have become evident in the standardization of uEV pipelines from collection of urine to biomarker analysis. Here, we studied the effect of pre-analytical variables and developed means of quality control for uEV isolates to be used in tra

RATIONALE: This study aimed to explore whether a computer-based training in eating and nutrition for hospital nursing staff can influence the precision in nutritional treatment and care.METHOD: A pre-intervention and post-intervention study was conducted with a cross-sectional design at each time point. The settings were one intervention (IH) and two control hospitals (CH1 and CH2). Hospital inpat

RATIONALE: A previous short-term study showed that a computer-based training in eating and nutrition increased the probability for hospital inpatients at undernutrition (UN) risk to receive nutritional treatment and care without increasing overtreatment (providing nutritional treatment to those not at UN risk). The aim of this study was to investigate if a computer-based training in eating and nut

Controlled generation and detection of quantum entanglement between spatially separated particles constitute an essential prerequisite both for testing the foundations of quantum mechanics and for realizing future quantum technologies. Splitting of Cooper pairs from a superconductor provides entangled electrons at separate locations. However, experimentally accessing the individual split Cooper pa

Background: Diagnosis and treatment of pharyngotonsillitis are commonly focused on group A streptococci (GAS), although the disease is often associated with other pathogens. While the incidence of pharyngotonsillitis is known to vary with season, seasonal variations in the prevalence of potential pathogens are sparsely explored. The aim of this study was to explore any seasonal variations in the u

BACKGROUND AND OBJECTIVES: To investigate the prevalence and trajectories of neuropsychiatric symptoms (NPS) in relation to cognitive functioning in a cohort of β-amyloid-positive (A+) individuals across the Alzheimer disease (AD) clinical spectrum. METHODS: In this single-center observational study, we included all individuals who visited the Alzheimer Center Amsterdam and had a clinical diagnosi

Background: To identify amino acids that can predict risk of 90-day mortality in patients with acute dyspnea. Method: Plasma levels of nine amino acids were analyzed 663 adult patients admitted to the Emergency Department (ED) with acute dyspnea. Cox proportional hazards models were used to examine the relation between amino acid levels and the risk of 90-day mortality. Result: Eighty patients (12

Background: People with substance use disorders (SUD) including patients in opioid substitution treatment (OST) are subject to stigma, and have generally poor health and barriers towards seeking healthcare. Experience of stigma might negatively affect healthcare seeking, but this topic is sparsely investigated. The aim of this study was to explore OST patients’ past and present experiences of subs

Den 7 oktober 2020 presenterades utredningen Ett särskilt hedersbrott, SOU 2020:57, med förslaget att låta brott med hedersmotiv utgöra en egen brottsrubricering. För att utreda om det vore befogat att införa lagförslaget i brottsbalken analyseras det utifrån några utvalda principer och teorier för kriminalisering. Trots att heder är ett problematiskt och svårdefinierat begrepp kan några karaktäOn October 7, 2020 the investigation Ett särskilt hedersbrott, SOU 2020:57, was presented, with a proposal to let crimes with honor motives constitute a specific criminal provision. In order to investigate if it would be justified to introduce in the Penal Code, the proposal will be analyzed on the basis of some selected principles and theories for criminalization. Although honor is a problemati

Var och en som anklagas för brott ska enligt Europakonventionen tillförsäkras rätten till en rättvis rättegång samt rätten att betraktas som oskyldig fram till dess att motsatsen bevisats. Genom denna oskyldighetspresumtion ska den tilltalade i en brottmålsrättegång inte behöva bevisa sig fri och har därför även rätten att vara tyst. Som en konsekvens av oskyldighetspresumtionen är det därför åklaAccording to the European Convention for the Protection of Human Rights and Fundamental Freedoms, everyone accused of a crime must be guaranteed the right to a fair trial and the right to be presumed innocent until proven guilty. Due to the presumption of innocence, the accused in a criminal trial should not have to prove his or her innocence and therefore also has the right to remain silent. As a

Entreprenadavtalet är en oreglerad avtalstyp. Enligt den tolkningsmetod som tillämpas på de standardavtal som reglerar majoriteten av kommersiella entreprenadavtal kan tolkningen av oklara villkor göras i ljuset av dispositiv rätt. Frågan är hur innehållet i den dispositiva entreprenadrätten ska fastställas. I NJA 2018 s. 653 valde HD att härleda en dispositiv entreprenadrättslig regel med stöd avThe construction contract is an unregulated type of contract. According to the principles of interpretation applied on the standard-form contracts that govern the majority of construction contracts, the interpretation of unclear terms can be made in the light of default law. An important question is how the default rules applicable on construction contracts are to be determined. In NJA 2018 s. 653

I uppsatsen undersöker jag juridiska överväganden kopplade till balansen mellan en personlig assistents anställningsskydd och rätten till självbestämmande för assistansanvändaren, dvs. personen med funktionsnedsättning. Yrket som personlig assistent innebär ett nära samspel mellan assistansanvändaren och den personliga assistenten. I många fall är en hälsosam yrkesrelation en förutsättning för såvIn this thesis I examine legal considerations concerning the balance between employment protection for personal assistants and self-determination for the service user, i.e. the person with a disability. Personal assistance as a profession entails a close relationship between the service user and the personal assistant. In many cases, a healthy relationship is a condition for the wellbeing of the p

Tillgreppsbrottslighet och ordningsstörningar som sker i svensk detaljhandel är en mångårig problematik som det vidtagits åtskilliga åtgärder gentemot. Butiksägares egendomsrätt kränks till följd av tillgreppsbrottslighet inom detaljhandeln. Den 1 mars 2021 trädde lag (2021:34) om tillträdesförbud till butik (”tillträdesförbudslagen”) i kraft. Lagen innebär att tillträdesförbud förenat med straffaCrime and disorderly conduct, which are affecting Swedish retail trade, have been a problem in which several preventive measures have been taken. The store owners right to property is violated as a result of the problem with crime in the retail trade. On March 1, 2021, law (2021:34) about admissibility to stores (“tillträdesförbudslagen”) came into force. The law means that a restraining order com