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Three fine grained WC-10 vol% Co cemented carbide materials were produced. One with 1 w% Cr addition, one with 0.025 w% Ti addition and one with both additions of 1 w% Cr and 0.025 w% Ti. It was found that doping of both Cr and Ti is advantageous for grain growth inhibition over just Cr- or Ti-doping. The impact of Cr and Ti as grain growth inhibitors on the residual stress state after sintering w
Cubosomes have emerged as a powerful platform for cancer treatment due to their biocompatibility and ability to encapsulate hydrophilic/lipophilic drugs, providing controlled drug release. While investigating these nanoparticles' stability and intracellular localization is essential for advancing them as clinically efficient nanomedicine, such studies are still lacking, and those available do not
In this short paper, we reflect on ‘algorithmic management learning’ – a phenomenon that dates back to the early twentieth century but has gained fresh impetus in the dawning age of artificial intelligence. In particular, we suggest that management learning has today become a human-machine hybrid. This form of management learning is not only increasingly non-reflexive, it is also impeding the huma
The ruling paradigm is that future climate change scenarios will lead to an increase in the frequency, intensity, and duration of cyanobacterial blooms across the globe. It was therefore unexpected when, during an unusually warm and dry summer in southern Sweden in 2018, cyanobacteria did not dominate the phytoplankton community of the temperate Lake Vombsjön known for toxic cyanobacterial blooms.
At the onset of the pandemic, Brazil’s Federal government approved an emergency basic income to be transferred to a variety of groups that had not earlier received any of the established welfare programs. Its implementation was however riddled with challenges. With a large informal economy, many Brazilian citizens were missing from the Federal Government’s registry and, even if registered, many di
We study whether one reason behind female underrepresentation in leadership is that female leaders are less effective at coordinating followers’ actions. Two experiments using coordination games investigate whether female leaders are less successful than males in persuading followers to coordinate on efficient equilibria. In these settings, successful coordination hinges on higher-order beliefs ab
In most clinical situations involving adenovirus infection, subgenus (subgroup) identification of an adenovirus isolate is as informative as a finer identification by serotype. A PCR method which allows the identification of human adenovirus isolates as members of subgenera A, B:1, B:2, C, D, E, or F is described. It is based on a simple (nonnested) PCR using primers which bind to regions immediat
This paper develops a model of human capital accumulation with on-the-job learning subject to obsolescence risk. The model analytically characterizes trade-offs of reforming the level of income tax progressivity and matches well income inequality in the US. An enriched version is used to quantitatively investigate optimal tax progressivity in the US. In contrast to standard models with exogenous i
We develop a long-horizon asset pricing model in which equity investments may damage future production/consumption possibilities through their climate impact. We derive a four-fund separation result and determine the stocks' equilibrium returns. Stocks that have a sufficiently adverse impact on the climate may appear to have positive alphas relative to the CAPM. We further link our equilibrium ret
This paper presents tractable two parameter stochastic processes of the drift-diffusion class in order to model economic processes with a focus on income. Starting from the resulting closed-form, cross-sectional distributions, easy-to-interpret expressions for mobility and inequality (including the popular Gini-coefficient) are derived. The general processes are applied to discuss income mobility
This paper presents a closed-form expression for the concave consumption function in a model with liquidity constraints and spanned labor and capital income risk. Local Marginal Propensities to Consume (MPCs) and buffer-stock savings are analytically characterized allowing to identify its determinants. Solutions for common examples of the Hyperbolic Absolute Risk Aversion (HARA) class are presente
Neutrophil granulocytes are specialized phagocytic cells that carry a collection of granules for regulated secretion, each with distinct constituents. The granules can be classified as azurophil (primary), developed first, followed in time by specific (secondary) granules gelatinase granules, and secretory vesicles. Stage- and tissue-specific transcription factors govern the successive expression
Azurocidin is a multifunctional endotoxin-binding serine protease homolog synthesized during the promyelocytic stage of neutrophil development. To characterize the biosynthesis and processing of azurocidin, cDNA encoding human preproazurocidin was stably transfected to the rat basophilic leukemia cell line RBL-1 and the murine myeloblast-like cell line 32D cl3; cell lines previously utilized to st
Neutrophils contain an assembly of granules destined for regulated secretion, each granule type with distinct constituents formed before terminal differentiation. The earliest granules are designated azurophil (primary), followed in time by specific (secondary), and gelatinase granules as well as secretory vesicles. Transcription factors regulate the genes for the granule proteins to ensure that e
Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to
