We report the discovery of a new planetary system with three transiting planets, one super-Earth and two sub-Neptunes, that orbit EPIC 249893012, a G8 IV-V evolved star (M = 1.05 ± 0.05 M, R = 1.71 ± 0.04 R, Teff = 5430 ± 85 K). The star is just leaving the main sequence. We combined K2 photometry with IRCS adaptive-optics imaging and HARPS, HARPS-N, and CARMENES high-precision radial velocity mea

The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) comprising 181,522 cases among 1,165,690 participants of predominantly European ancestry. We detected 241 associations, including 30 new loci. Cross-ancestry meta-analysis with a

Background: Tissue factor is the main initiator of blood coagulation, and tissue factor pathway inhibitor (TFPI) is the primary inhibitor of the initiation of blood coagulation. The genetic variation of TFPI and the relation to venous thromboembolism (VTE), that is, venous thrombosis and pulmonary embolism, remains to be clarified. This exome sequencing study aimed to determine the molecular epide

The impact of somatic structural variants (SVs) on gene expression in cancer is largely unknown. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole-genome sequencing data and RNA sequencing from a common set of 1220 cancer cases, we report hundreds of genes for which the presence within 100 kb of an SV breakpoint associates with altered e

Large-scale gene sequencing studies for complex traits have the potential to identify causal genes with therapeutic implications. We performed gene-based association testing of blood lipid levels with rare (minor allele frequency < 1%) predicted damaging coding variation by using sequence data from >170,000 individuals from multiple ancestries: 97,493 European, 30,025 South Asian, 16,507 African,

Title: Women entrepreneurship - A multiple case study on financing decisions of women-owned startups Seminar date: January 11th, 2023 Course: FEKH99, Bachelor Degree Project in Entrepreneurship and Innovation, Business Administration, undergraduate level, 15 University credit points Authors: Agnes Carenborn, Fredrik Melander and Hugo Landén Advisor: Joakim Winborg Keywords: Women entrepreneurs, w

Background: Birds have extremely elevated metabolic rates during migratory endurance flight and consequently can become physiologically exhausted. One feature of exhaustion is oxidative damage, which occurs when the antioxidant defense system is overwhelmed by the production of damaging reactive oxygen species (ROS). Migrating birds have been shown to decrease the amount of oxidative lipid damage

Background: Direct-to-consumer telemedicine (TM), with patients having access to a physician via video or text chat, has gradually been introduced into Swedish primary care during the last two decades. Earlier studies have concluded that patients were generally satisfied with TM and the satisfaction rate was consistently above 80% and comparable with in-person visits. Despite the number of studies

The transport sector accounted for 37% of global CO2 emissions from end-use sectors in 2021. For the transport- and road freight sector to contribute to emissions reduction targets while still meeting the foreseen increase in transport demands, decarbonization will play a key role. This study focus on battery-electric heavy-duty trucks and the objective is to provide an overview of policy instrume

Biografisk artikel om latinaren, läroverksläraren, professorn, ordensgrundaren m m Carl Magnus Zander (1845-1923).

Understanding the link between titanium-aluminium nitride's (Ti1-xAlxN) physicochemical properties and structural dynamics during operation is essential to designing and fabricating advanced ceramic coatings. Here, we directly visualise the oxidation of Ti1-xAlxN (for x = 0, 0.18, 0.44, & 0.67) coatings from 100 to 1000 °C using environmental transmission electron microscopy (ETEM) imaging and

We report the discovery of a planetary system orbiting TOI-763(aka CD-39 7945), a V = 10.2, high proper motion G-type dwarf star that was photometrically monitored by the TESS space mission in Sector 10. We obtain and model the stellar spectrum and find an object slightly smaller than the Sun, and somewhat older, but with a similar metallicity. Two planet candidates were found in the light curve t

K2-146 is a cool, 0.358M⊙ dwarf that was found to host a mini-Neptune with a 2.67 day period. The planet exhibited strong transit timing variations (TTVs) of greater than 30 minutes, indicative of the presence of an additional object in the system. Here we report the discovery of the previously undetected outer planet in the system, K2-146 c, using additional photometric data. K2-146 c was found t

Quantum control is implemented in a 2-beam fs/ns rotational CARS setup via a second control pulse with variable delay. The potential of the concept for improved diagnostics is demonstrated by species-selective enhancement/annihilation via field-free alignment.