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Type 1 conventional dendritic cells (cDC1s) are rare immune cells critical for the induction of antigen-specific cytotoxic CD8+ T cells, although the genetic program driving human cDC1 specification remains largely unexplored. We previously identified PU.1, IRF8, and BATF3 transcription factors as sufficient to induce cDC1 fate in mouse fibroblasts, but reprogramming of human somatic cells was lim

Research shows that resistance to change might occur in organisations that implement new evidence-based practices (EBP). Formal and informal structures may work to retain traditional interventions, potentially counteracting the implementation process. Little is known about the de-implementation of traditional practices to leave room for and enhance the implementation of EBPs. This study uses imple

South Korea and Singapore have established a reputation as top performers in international student assessment tests and rankings, which is usually understood to be the result of competitive education systems and a distinct parenting culture. They also share a large private tuition industry, fueled by parents’ anxiety over their children’s academic achievements and future. In an attempt to contest South Korea and Singapore have established a reputation as top performers in international student assessment tests and rankings, which is usually understood to be the result of competitive education systems and a distinct parenting culture. They also share a large private tuition industry, fueled by parents’ anxiety over their children’s academic achievements and future. In an attempt to contest

Questions around parental involvement in education, not only in in East Asia but also in a global context, are significant, given the increased concern in ‘population quality’ and the ever-growing education market. South Korea and Singapore are widely recognized for their competitive education systems and for consistently topping international student assessment tests. They also share a ballooningQuestions around parental involvement in education, not only in in East Asia but also in a global context, are significant, given the increased concern in ‘population quality’ and the ever-growing education market. South Korea and Singapore are widely recognized for their competitive education systems and for consistently topping international student assessment tests. They also share a ballooning

South Korea and Singapore are widely recognized for their competitive education systems and for consistently topping international student assessment tests. They also share a ballooning private tuition industry, fueled by parents’ anxiety over their children’s academic achievements. This paper is based on a comparative ethnographic study on parenting strategies around young children’s (aged 4-12)

The size, structure and ‘quality’ of the population are issues of concern in contemporary East Asia, as the region is becoming enmeshed with the global economy, and competitiveness increasingly centers on ‘a fitting’ human capital. While Singapore is located in Southeast Asia geographically speaking, it is culturally linked to East Asia in terms of its heritage of Confucianism and the Chinese lang

European infrastructure managers (IMs) create annual timetables for trains that will run during a year. Freight trains in Sweden often deviate from this by being added, cancelled, delayed or early, resulting in increased costs for IMs and railway undertakings (RUs). We investigate the frequency of and causes for these deviations, using one year of operational data for 48,000 trains, and 15 stakeho

High-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare decisions oBackgroundHigh-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare d

This work aims at clarifying the fundamental mechanisms of non-equilibrium alternating current gliding arc discharge (GAD) by investigating effects of gas compositions and pressures on the GAD characteristics with electrical and optical methods. Interestingly, the glow-to-spark transition was found by adding O2 or CH4 into the argon or modulating the power supply. This transition occurs attributed

Precise control of the discharge in space and time is of great significance for better applications of discharge plasma. Here, we used a femtosecond laser filament to trigger and guide a high-voltage DC pulse discharge to achieve spatiotemporal control of the discharge plasma. In space, the discharge plasma is distributed strictly along the channel generated by the femtosecond laser filament. The

In 2011, the Russian government, in order to mark the 100th anniversary of Swedish Diplomat Raoul Wallenberg, decided to allow one Swedish researcher to go through the diplomatic correspondence in cipher between the Soviet Embassy in Stockholm and the Soviet Foreign Ministry during the years 1944–1947. This article presents some of the major findings on Wallenberg and discusses whether parallel pa

In March 1946 the Soviet government decided to radically revise their policy towardsSweden. The Soviet demand, ever since November 1944, for the total extradition ofthe approximately 30,000 Baltic refugees in Sweden was suddenly dropped and anumber of measures were taken by Moscow to accomplish a rapprochement betweenthe two countries. On the basis of recently declassified Soviet encrypted diploma

Fredagen den 3 augusti 1923 klev en 17-årig smålänning av Svenska Amerika Liniens S/S Drottningholm i New York. Han genomgick procedurerna på Ellis Island, fick en adresslapp på kavajslaget, roddes i land, marscherade med andra nyanlända på led till Grand Central Station, sattes på ett tåg norrut och lyftes av i New Haven, Connecticut. De närmaste tio åren skulle han uppleva det glada 20-talet och

This article addresses the claim made by the American journalistsFrederick Werbell and Thurston Clarke (in 1982) and the Swedishauthor and researcher Bengt Jangfeldt (in 2012) to the effect thatthe Swedish diplomat Raoul Wallenberg, when preparing to leaveBudapest for Debrecen in January 1945, hid jewelry and 15–20 kgof gold in his car. As is evident from the examination conductedhere, the testimo

Hvis man vil forstå, hvad det vil sige at være menneske, kommer man ikke uden om at beskæftige sig med den menneskelige bevidsthed. Det er den, der gør os til den, vi hver især er, og der er den, som gør, at mennesker har udviklet alt lige fra redskaber og maskiner til kunst og videnskabelige teorier. Det er bevidstheden, der gør, at nogle ting er vigtige for os, at vi har drømme og håb. Når vi pr