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Older people's views of prioritization in health care. The applicability of an interview study.

Aim. Older people's views of prioritization in health care. The applicability of an interview study. Old age has been stated as a criterion for prioritization in health care, although older people are seldom asked for their opinions. The aim of this pilot study was to investigate the applicability of a questionnaire as a base for an interview study to explore older people's experiences and views o

Growth hormone treatment in 35 prepubertal children with achondroplasia: A five-year dose-response trial

Background: Achondroplasia is a skeletal dysplasia with extreme, disproportionate, short stature. Aim: In a 5-y growth hormone (GH) treatment study including 1 y without treatment, we investigated growth and body proportion response in 35 children with achondroplasia. Methods: Patients were randomized to either 0.1 IU/kg (n=18) or 0.2 IU/kg (n=17) per day. GH treatment was interrupted for 12 mo af

Muon pair production in ep collisions at HERA

Cross sections for the production of two isolated muons up to high di-muon masses are measured in ep collisions at HERA with the H1 detector in a data sample corresponding to an integrated luminosity of 71 pb(-1) at a centre of mass energy of roots = 319 GeV. The results are in good agreement with Standard Model predictions, the dominant process being photon-photon interactions. Additional muons o

Discrete wave-analysis of continuous stochastic processes

he behaviour of a continuous-time stochastic process in the neighbourhood of zero-crossings and local maxima is compared with the behaviour of a discrete sampled version of the same process.For regular processes, with finite crossing-rate or finite rate of local extremes, the behaviour of the sampled version approaches that of the continuous one as the sampling interval tends to zero. Especially t

p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils.

Neutrophil apoptosis occurs both in the bloodstream and in the tissue and is considered essential for the resolution of an inflammatory process. Here, we show that p38–mitogen-activated protein kinase (MAPK) associates to caspase-8 and caspase-3 during neutrophil apoptosis and that p38-MAPK activity, previously shown to be a survival signal in these primary cells, correlates with the levels of cas

Selective Generation of Gut Tropic T Cells in Gut-associated Lymphoid Tissue (GALT): Requirement for GALT Dendritic Cells and Adjuvant.

n the current study, we address the underlying mechanism for the selective generation of gut-homing T cells in the gut-associated lymphoid tissues (GALT). We demonstrate that DCs in the GALT are unique in their capacity to establish T cell gut tropism but in vivo only confer this property to T cells in the presence of DC maturational stimuli, including toll-like receptor-dependent and -independent

Norm-dependent random matrix ensembles in external field and supersymmetry

The class of norm-dependent random matrix ensembles is studied in the presence of an external field. The probability density of the ensemble depends on the trace of the squared random matrices, but is otherwise arbitrary. An exact mapping to superspace is performed. A transformation formula is derived which gives the probability density in superspace as a single integral over the probability densi

Polybrominated diphenyl ethers (PBDES) at a solid waste incineration plant I: Atmospheric concentrations

In the first of two papers, the atmospheric poly brominated diphenyl ether (PBDE) concentrations at a municipal solid waste incineration (MSW) plant with electronic recycling is compared with that at an industrial urban reference site producing asphalt and concrete. In the second paper, atmospheric deposition and washout behaviour is presented (Atmos. Environ. (2004a)). PBDEs (BDE28, -47, -66, -10

Interaction of metals and thiols in cell damage and glutathione distribution: potentiation of mercury toxicity by dithiothreitol

In the present study, we have investigated the effects of extracellular redox status and metal/thiol interactions on glutathione distribution in HeLa cell cultures. No effects were seen on glutathione distribution after the addition of different thiols, whereas the pro-oxidant copper ions affected glutathione distribution in several ways. The addition of dithiothreitol (DTT) but not the other thio

Crystal structure of a mutant elongation factor G trapped with a GTP analogue

Elongation factor G (EF-G) is a G protein factor that catalyzes the translocation step in protein synthesis on the ribosome. Its GTP conformation in the absence of the ribosome is currently unknown. We present the structure of a mutant EF-G (T84A) in complex with the non-hydrolysable GTP analogue GDPNP. The crystal structure provides a first insight into conformational changes induced in EF-G by G

Silica filled poly(1-trimethylsilyl-1-propyne) nanocomposite membranes: Relation between the transport of gases and structural characteristics

The performance of poly(1-trimethylsilyl-1-propyne) (PTMSP)/silica nanocomposites was studied for membranes with a filler content between 0 and 50 wt%. An increase in permeability and a decrease in vapor selectivity was measured with increasing filler content. The free volume sizes and interstitial mesopore sizes of the composites were determined by use of positron annihilation lifetime spectrosco

Word final aspiration as a phrase boundary cue: Data from spontaneous Swedish discourse

The Swedish sound string /at/ (graphically: att) is associated with two grammatical functions: a) (part of) a subordinate conjunction and b) as an infinitive marker. Previous studies connect final lengthening and pauses with prosodic and syntactic boundaries in spoken discourse. Following these findings, this pilot study, with 5 short spontaneous discourses from 3 male speakers shows a correlation

Omorganisationer, kvalitet och arbetsmiljö i hemtjänsten under 1990-talet

Omorganisationer i form av marknadsorienterade beställar-utförarmodeller och effektivisering har sedan början av 1990-talet fått mycket stor omfattning inom offentlig sektor. De startade utan några vetenskapliga stöd för att de nya formerna skulle resultera i bättre kvalitet i tjänsterna. Resultat från en tioårig empirisk studie inom hemtjänsten pekar i stort på ingen eller negativ inverkan på arb