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Special issue : Therapy-induced remodeling of the tumor microenvironment
A Numerical Model to Simulate Beach and Dune Evolution
A numerical model to simulate cross-shore (CS) beach and dune evolution induced by storms was developed in this study. The model development was partly based on previous CS modeling work in which modules describing the response of the beach profile in the offshore, surf, and swash zone were described in detail, but where the dune module is lacking. The dune module, adopting wave impact theory, was
Dendrokronologisk analys av en stenkista vid hamnanläggningen vid Näsborgen på Visingsö
Stable isotope record from a resident New Zealand seabird community suggests changes in distribution but not trophic position since 1878
Globally, human population growth, its associated pollution and the vast scale of industrialised fisheries are having negative impacts on oceanic food webs, affecting top predators such as seabirds. We used stable isotope (δ15N and δ13C) analyses of feathers to investigate the contemporary structure and long-term changes in a near-shore community of 5 seabird species in northern Aotearoa New Zeala
Technologically mediated tourist experiences: the tourist and the smartphone
As smart and as stupid, as well- and ill-informed, as curious and closed-minded as any random sample, tourists represent a unique object of study, as they are “the last remaining class that exhibits consciousness for itself” (MacCannell, 2013 p.xix). Technology has been transforming the tourist experience deeply, as it both fulfils a functional purpose of performing tasks for humans, and it holds
Introduction to Preschool During the Covid-19-Pandemic: Impacts of Social Restrictions on Staff-Family Relational Establishment
The social restrictions during the covid-19 pandemic have challenged many aspects of preschool everyday life. Particularly vulnerable to these restrictions is the aspect of introducing new children to preschool, since preschool introduction constitutes a natural arena for establishment of preschool staff’s relationships with children and their parents. Organizing the preschool introduction to enab
Historical ideas of sustainability and future Mars exploration policies
Effects of a National Preventive Intervention Against Potential COVID-19-Related Gambling Problems in Online Gamblers : Self-Report Survey Study
Background: The COVID-19 pandemic has been suspected to increase gambling problems in the population. Several governments introduced COVID-19-specific interventions early with the aim to prevent gambling problems, but their effects have not been evaluated. Objective: This study aimed to evaluate a Swedish COVID-19-related temporary legislation imposing an automated weekly deposit limit for online
Microvascular Changes in Parkinson’s Disease- Focus on the Neurovascular Unit
Vascular alterations emerge as a common denominator for several neurodegenerative diseases. In Parkinson’s disease (PD), a number of observations have been made suggesting that the occurrence of vascular pathology is an important pathophysiological aspect of the disease. Specifically, pathological activation of pericytes, blood-brain barrier (BBB) disruption, pathological angiogenesis and vascular
Lateralized Readiness Potentials Recorded with Near-Threshold Auditory Stimuli in Subjects Simulating Hearing Loss
Introduction: Preparatory motor cortical responses like the lateralized readiness potential (LRP) may be useful in revealing persistent attempts to feign hearing loss. Previous studies suggest only a marginal effect of stimulus intensity on the amplitude of the LRP. However, this has not been investigated using low-intensity auditory stimuli to cue NoGo trials. We address this in an experiment whe
The Value of Nonpharmacological Interventions for People With an Acquired Brain Injury: : A Systematic Review of Economic Evaluations
Objectives: Acquired brain injury (ABI) has long-lasting effects, and patients and their families require continued care andsupport, often for the rest of their lives. For many individuals living with an ABI disorder, nonpharmacologicalrehabilitation treatment care has become increasingly important care component and relevant for informed healthcaredecision making. Our study aimed to appraise econ
Remissyttranden: Grundläggande omställnings- och kompetensstöd - för flexibilitet, omställningsförmåga och trygghet på arbetsmarknaden (Ds 2021:16) : A2021/01333 Dnr V 2021/1940
Infection is associated with increased risk of MPO- but not PR3-ANCA associated vasculitis
ObjectivesTo determine whether development of ANCA–associated vasculitis (AAV) shows a relationship to a prior infection and if prior infection affects disease characteristics and outcome.MethodsAll incident cases of AAV diagnosed in a defined region of Sweden from 2000 through 2016 were identified. For each case, 10 individuals from the general population, matched for age, sex, and area of reside
Sources of dietary gluten in the first two years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisosed children: : TEDDY study
BackgroundHigh gluten intake is associated with increased risk of celiac disease (CD) in children at genetic risk.ObjectivesTo investigate if different dietary gluten sources up to age two years confer different risks of celiac disease autoimmunity (CDA) and CD in children at genetic risk.DesignThree-day food records were collected at age six, nine, 12, 18 and 24 months from 2088 Swedish genetical
Towards Single-Ion Detection and Single-Photon Storage in Rare-Earth-Ion-Doped Crystals
Solid materials doped with rare-earth ions are considered an attractive platform for quantum information applications. One of the main reasons for this is the exceptionally long optical and hyperfine coherence times of the 4fn states, due to the shielding provided by the outer lying 5s and 5p electrons. This enables a large number of quantum operations before the system loses its coherence. Anothe
Engineering Saccharomyces cerevisiae for production of the capsaicinoid nonivamide
BackgroundCapsaicinoids are produced by plants in the Capsicum genus and are the main reason for the pungency of chili pepper fruits. They are strong agonists of TRPV1 (the transient receptor potential cation channel subfamily V member 1) and used as active ingredients in pharmaceuticals for the treatment of pain. The use of bioengineered microorganisms in a fermentation process may be an effi
Diffusion MRI of Brain Tissue: Importance of Axonal Trajectory
Obtaining microstructural information non-invasively on brain tissue remains a challenge. Diffusion magnetic resonance imaging (dMRI) is an imaging method that can provide such information. That includes geometrical considerations of nerve cells projections, axons, that are present in the white matter of the human brain. Axons carry information encoded into electrical impulses to other cells.The t
Novel, original, and business as usual : Contributing in the humanities
This paper focuses on how contributions are argued in research proposals in the humanities. Due to standardizing tendencies in research funding towards formats characteristic of science, technology, engineering and mathematics (STEM) subjects, there has been concern that the humanities are marginalized. In this study, ‘contribution statements’ were identified in proposals funded by the Bank of Swe
The development of the pilot emission trading in developing China
The Chinese government is acutely aware of the problem of climate change. In the crucial crossroads, carbon emissions trading scheme (ETS), a kind of market-based instruments based on cap-and-trade, has become the new hope of carbon governance and the most important measure adopted to mitigate climate change. Based on the description and analysis on the ongoing process of pilot ETS in China and it