Filtyp
Denna rapport redovisar en förstudie till SNS fleråriga forskningsprojekt som undersöker hur värdet av nya läkemedel kan bedömas ur ett brett samhällsperspektiv. En slutsats av förstudien är att det finns goda möjligheter att få bättre svar på många av de policyfrågor som ställs i läkemedelspolitiken, t ex om förskrivning och offentlig subventionering av nya läkemedel. De omfattande svenska patien
The goal of this work is to explore ways of generating state trajectories for dynamical systems subject to computational constraints, obstacles and priority assignment. The algorithms are developed for a miniature unmanned aerial vehicle (UAV) in a modular fashion and include (1) a genetic algorithm (GA) for solving the traveling salesman problem (TSP) with respect to priorities and obstacle avoid
A plethora of studies have shown that the physicochemical properties of oat β-glucan determine its health benefits. However, the impact of the passage through the gastrointestinal tract on the conformational and structural characteristics is not fully understood. The present study aims to elucidate the structure and conformation of gently extracted oat β-glucan before and after in vitro gastric an
Myndigheten för samhällsskydd och beredskap (MSB) har efterfrågat synpunkter av Lunds Tekniska Högskola på det rapporteringsverktyg för risk- och sårbarhetsanalyser som MSB utvecklar. Verktyget är tänkt att underlätta förmedling och insamling av information som framkommer genom de risk- och sårbarhetsanalyser som kommuner och landsting samt myndigheter upprättar enligt föreskrifterna MSBFS 2010:6
This study contributes to the establishment of frequency recommendations for use in coda wave interferometry structural health monitoring (SHM) systems for concrete structures. To this end, codas with widely different central frequencies were used to detect boreholes with different diameters in a large concrete floor slab, and to track increasing damage in a small concrete beam subjected to bendin
Diffuse ultrasonic wave measurements used in structural health monitoring applications can detect damage in concrete. However, the accuracy is very susceptible to environmental variations. In this study, a large concrete floor slab was monitored using diffuse wave fields that were generated by continuous-wave transmissions between ultrasonic transducers. The slab was monitored for several weeks wh
Computational modelling of neurons on different scales provides not only methods to explore mechanisms observed in vivo but also for testing hypotheses that would be impossible physiologically. In this paper we present initial computational analysis of insect lobula small target motion detector (STMD) neurons. We simulate a multicompartment model in combination with a bioinspired model for front-e
Preparative liquid chromatography is a separation technique widely used in the manufacturing of fine chemicals and pharmaceuticals. A major drawback of traditional single-column batch chromatography step is the trade-off between product purity and process performance. Recirculation of impure product can be utilized to make the trade-off more favorable. The aim of the present study was to investiga
Partially Premixed Combustion (PPC) is an advanced combustion concept resulting in high efficiencies and low emission levels by the use of high levels of EGR and pilot injections. The main limitation of PPC to use in practice lies in the high pressure rise rate, which causes issues on engine noise and durability. In addition, soot emissions face with the overshoot problem during the transient oper
Our previous research investigated the sensitivity of combustion phasing to intake temperature and injection timing during the transition from homogeneous charge compression ignition (HCCI) to partially premixed combustion (PPC) fuelled with generic gasoline. The results directed particular attention to the relationship between intake temperature and combustion phasing which reflected the changing
In spite of the importance of the triglyceride aqueous interface for processes like emulsification, surfactant interactions and lipase activity, relatively little is known about this interface compared to that between alkanes and water. Here, the contact between triolein and water was investigated in terms of water inclusion in the oil phase and orientation of the molecules at the interface. Coars
The integrated dynamic ecosystem models SAFE and ForSAFEVEG were used to estimate critical loads for nitrogen using different chemical and biological criteria, and attempting to account for possible effects of climate change. The study is based on a model application on a set of 640 sites earlier used for critical loads assessments in Sweden, focusing on the ecological effect of nitrogen pollution
Quite recently, the Ioncell-F process, a novel and promising Lyocell fibre process, has been developed. The ionic liquid 1,5-diazabicyclo[4.3.0]non-5-enium acetate ([DBNH]OAc) utilized in this process, was identified as an excellent cellulose solvent for dry-jet wet fibre spinning. Fibres spun from cellulose-[DBNH]OAc solution have shown excellent mechanical properties. Herein, various structural
Accelerated cellular aging and reduced lifespan have recently been shown in birds chronically infected with malaria parasites. Whether malaria infection also affects cellular aging in humans has not been reported. Here, we assessed the effect of a single acute Plasmodium falciparum malaria infection on cellular aging dynamics in travelers prospectively followed over one year in Sweden. DNA and RNA
Liposomes are considered a major route for encapsulation of hydrophilic and hydrophobic molecules. Chitosan coated liposomes could represent an alternative way as a carrier for delivery of drugs in human body. In this study the preparation and applicability of chitosan-coated liposomes containing curcumin as well as curcumin loaded anionic liposomes were evaluated. The applicability of the carrier
The study assesses the performance of experimental wetland pond systems vegetated by Lemna minor L. (common duckweed or lesser duckweed) for textile azo dye removal. The objectives are to assess the influence of L. minor on water quality parameters, compare the dye and chemical oxygen demand (COD) removal of four dyes (Acid Blue 113, Reactive Blue 198, Direct Orange 46 and Basic Red 46) with each
We argue that the meanings of demonstratives and articles can be analysed in terms of a combination of the spatial domain and a small set of semantic domains. We propose that deictic terms have a 'fast semantics' in the sense that they get their meaning in the course of the communicative act, as a result of an interaction between the interlocutors, which ultimately leads to referential anchoring.
