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Sag-rad : A Method for Single-Cell Population Genomics of Unicellular Eukaryotes

Sequencing of reduced representation libraries enables genotyping of many individuals for population genomic studies. However, high amounts of DNA are required, and the method cannot be applied directly on single cells, preventing its use on most microbes. We developed and implemented the analysis of single amplified genomes followed by restriction-site-associated DNA sequencing to bypass labor-in

Peter Bengtsen : Researching Street Art

In this article, Peter Bengtsen, who has written several books on street art, approaches the topic of Street Art, Science and Engagement as an academic. He discusses how he became interested in environmental street art, how his research developed and how and to what extent environmental street art can influence the viewer and bring about positive behavioural change. Unpacking selected internationa

Restoring tumor immunogenicity with dendritic cell reprogramming

Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen-presenting cells (tumor-APCs). Enforced expression of the transcription factors PU.1, IRF8, and BATF3 (PIB) was sufficient to induce the cDC1 phenotype in 3

COVID-19 risk perception and public compliance with preventive measures : evidence from a multi-wave household survey in the MENA region

This study investigates the association between individuals’ concern about contracting COVID-19 and their compliance with recommended preventive and mitigation measures, namely wearing face masks, maintaining social distancing and handwashing, in the context of the Middle East and North Africa (MENA) region. The empirical analysis is based on a panel dataset from the Combined COVID-19 MENA Monitor

Regulation of osteoblast to osteocyte differentiation by cyclin-dependent kinase-1

Osteocytes have recently been identified as a new regulator of bone remodeling, but the detailed mechanism of their differentiation from osteoblasts remains unclear. The purpose of this study is to identify cell cycle regulators involved in the differentiation of osteoblasts into osteocytes and determine their physiological significance. The study uses IDG-SW3 cells as a model for the differentiat

Population-based prognostic instrument (SweMR 2.0) for melanoma-specific survival - An ideal tool for individualised treatment decisions for Swedish patients

INTRODUCTION: The prognosis for patients with melanoma has improved due to better treatments in recent years and updated tools to accurately predict an individual's risk are warranted. This study aims to describe a prognostic instrument for patients with cutaneous melanoma and its potential as a clinical device for treatment decisions.METHODS: Patients with localised invasive cutaneous melanoma di

My Religious Identity : An Unfinished Project

Abstract in NorweiganSammenfatning: Spørsmålet om identitet er alltid tilstedei akademiske og ikke-akad-emiskediskurser om religion og interreligiøse relasjoner: identitet som en kategori av noe som kan spigles fast, etableres ogopprettholdes ved hjelp av de"nisjonerog logikk; identitet som et spørsmål om noe stabilt og til og med rigid. Detteer viktig i overveielser omsynkretisme. I denne artikkeThe matter of identity is ever present in academic, and non-academic, discourses on religion and interreligious relations: identity as a category of something that can be nailed down, established and maintained with the help of definitions and logic; identity as a matter of something stable and even rigid. This is significant in deliberations regarding syncretism. In this paper, references are mad

Greening monies: Remaking money for a sustainable future

A variety of complementary monies are being implemented as socio-technical instruments to move individuals into action and ignite ecological collaboration. Their starting point is the recognition that we have never been modern; that human society and nature, the economy and the environment, have never been separate spheres. Modernism may have conceptualised them as distinct fields, organising the

Concordance of International Regulation of Pediatric Health Research

Objective: To assess the comparability of international ethics principles and practices used in regulating pediatric research as a first step in determining whether reciprocal deference for international ethics review is feasible. Prior studies by the authors focused on other aspects of international health research, such as biobanks and direct-to-participant genomic research. The unique nature of

Public diplomacy bridging ideological difference: affinity vs confrontational approaches

This paper explores the content and style of two communicative approaches to public diplomacy intended to mitigate ideological tensions between countries. The aim of the paper is to contribute to new knowledge of public diplomacy as cultural practice by examining the characteristics of its enactment and consequences for the public debate in domestic and foreign contexts.

Identification and quantification of degradome components in human synovial fluid reveals an increased proteolytic activity in knee osteoarthritis patients vs controls

Synovial fluid (SF) may contain cleavage products of proteolytic activities. Our aim was to characterize the degradome through analysis of proteolytic activity and differential abundance of these components in a peptidomic analysis of SF in knee osteoarthritis (OA) patients versus controls (n = 23). SF samples from end-stage knee osteoarthritis patients undergoing total knee replacement surgery an