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Clinical progression in early and late stages of disease in a cohort of individuals infected with human immunodeficiency virus-2 in Guinea-Bissau

The aim of this study was to assess the rate of clinical progression to early and late stages of human immunodeficiency virus-2 (HIV-2) infection. CD4 cell counts and other potential prognostic markers for disease progression were also evaluated. In January 1990 an open prospective cohort of police officers in Guinea-Bissau was initiated with yearly serological and clinical follow-up. Follow-up en

Characterization of Lyme borreliosis isolates from patients with erythema migrans and neuroborreliosis in southern Sweden

Southern Sweden is an area of Lyme borreliosis (LB) endemicity, with an incidence of 9 cases per 100,000 inhabitants. The most frequent clinical manifestations are erythema migrans (77%) and neuroborreliosis (16%). There was no record of human Borrelia strains being isolated front patients in this region before the prospective study reported here. Borrelia spirochetes were isolated from skin and c

"Vi kanske kommer igen, om det låser sig" : Kvinnors och mäns möte med familjerådgivning.

Popular Abstract in Swedish Kring familjeproblematiken och för behandlingen av familjekonflikter har det svenska samhället organiserat olika sociala verksamheter som traditionellt regleras av Socialtjänstlagen. Familjerådgivningen är en av dessa verksamheter och definieras som en psykoterapeutisk behandling, till vilken en eller båda parter vänder sig oftast på frivillig basis när de upplever att This dissertation is the result of an evaluation of family counselling (FC) in a middle-sized city in Sweden. The findings support results from earlier studies of family counselling which indicate that people have a positive attitude to counselling. But this finding led to questions that remained unanswered in earlier research. What is it particularly in FC treatment that brings about a result, wh

New laboratory lifetime measurements of U II for the uranium cosmochronometer

We present new measurements of radiative lifetimes for six energy levelsof singly ionized uranium, U II, using laser-induced fluorescencetechnique. One of the levels,5f36d7p6M13/2 at 26191 cm-1,decays by a transition at 3859.6 Å. This line has recently beenobserved in the spectrum of the metal-poor star CS1082-001, the firstdetection of uranium outside the solar system. The lambda 3859 line canbe

Constraints-driven scheduling and resource assignment

This paper describes a new method for modeling and solving different scheduling and resource assignment problems that are common in high-level synthesis (HLS) and system-level synthesis. It addresses assignment of resources for operations and tasks as well as their static, off-line scheduling. Different heterogeneous constraints are considered for these problems. These constraints can be grouped i

Evaluation of heterogeneity of DNA ploidy in early gastric cancers

DNA ploidy has been shown to be a predictive parameter for prognosis in various solid tumours. The prognostic value of DNA-ploidy in gastric cancers is still a matter of controversy. A possible explanation for the discrepant results reported in the literature could be sampling error in tumours with multiple stemlines differing in DNA-ploidy. In order to determine whether or not such heterogeneity

Urodynamic effects of the K+ channel (KCNQ) opener retigabine in freely moving, conscious rats.

Purpose: Retigabine is a novel anticonvulsant drug that not only augments gamma-aminobutyric acid mechanisms, but also opens voltage gated K+ channels (KCNQ). In this study we investigated the effects of retigabine on detrusor activity in rats. Materials and Methods: To conscious, female Sprague-Dawley rats undergoing continuous cystometry retigabine was given intravenously (0.5, 1 and 5 mg/kg(-1)