Objective. To study the impact of disease and treatment with DMARDs on antibody response elicited by either pneumococcal conjugate vaccine (PCV13) or pneumococcal polysaccharide vaccine (PPV23) in patients with SSc. Methods. Forty-four SSc patients and 49 controls received a dose of either PCV13 or PPV23. Twelve patients were treated with DMARDs. Antibody levels to pneumococcal polysaccharides 6B

While general trends in Central European postglacial recolonisation dynamics are relatively well known, we often lack studies on intermediate (meta-population, landscape) scales. Such studies are needed to increase our understanding of, for example, the location of refugia; emergence of endemism, rates and trajectories of postglacial migrations; and anthropogenic landscape changes. Here, we focuse

Objective Factors predicting survival over time after pediatric intensive care unit (PICU) admissions are not fully understood. The primary aim of the current study was to investigate whether multiple admissions (MADM) compared to single PICU admissions (SADM) were associated with poor survival over time after being admitted to PICU facilities. Our secondary aim was to investigate if the presence

This article aims to present the protocol on Quality Controls in Digital Mammography published online in 2015 by the European Federation of Organisations for Medical Physics (EFOMP) which was developed by a Task Force under the Mammo Working Group. The main objective of this protocol was to define a minimum set of easily implemented quality control tests on digital mammography systems that can be

The Alzheimer's Association's Research Roundtable met in November 2017 to explore the new National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease. The meeting allowed experts in the field from academia, industry, and government to provide perspectives on the new National Institute on Aging and the Alzheimer's Association Research Framework. This revie

A global approach coupling the moderator to the beam extraction system has been applied for the design optimization of the thermal and cold moderators of the European Spallation Source (ESS), which will be the brightest neutron source in the world for condensed-matter studies. The design is based on the recently developed high-brightness low-dimensional moderator concepts. Para-hydrogen is used fo

Människans vilja att förstå universums mest fundamentala byggstenar och dess naturlagar är den drivkraft som ligger till grund för elementarpartikelfysiken. Den teoretiska forskningen inom detta område vägleds idag till stor del av data från LHC-experimentet utanför Genève (LHC förkortar `Large Hadron Collider', dvs.~den Stora Hadronacceleratorn). Vid LHC accelereras protoner till extremt höga hasThe four articles contained in this thesis all concern aspects of model building beyond the Standard Model (BSM). While Paper I mainly serves as a ``tool paper'' in which the results can be used to simplify certain calculations of one-loop effects from new heavy particles, Paper II--IV all deal with consequences of family symmetries in several BSM scenarios. Paper I. We derive expressions for any

Time series from Landsat and Sentinel-2 satellites have great potential for modeling vegetation seasonality. However, irregular time sampling and frequent data loss due to clouds, snow, and short growing seasons, makes this modeling a challenge. We describe a new method for modeling seasonal vegetation index dynamics from satellite time series data. The method is based on box constrained separable

This paper offers a formally driven quantitative analysis of stance-annotated sentences in the Brexit Blog Corpus (BBC). Our goal is to identify features that determine the formal profiles of six stance categories (CONTRARIETY, HYPOTHETICALITY, NECESSITY, PREDICTION, SOURCE OF KNOWLEDGE and UNCERTAINTY) in a subset of the BBC. The study has two parts: firstly, it examines a large number of formal

The Inter- American Court of Human Rights has developed an interpretative approach in the recent years that considers all international instruments that deliver protection to human beings as part of the same legal system, that is, the corpus juris of international human rights law. Consequently, different branches of international law, such as international humanitarian law, refugee law, consular

Self‐reported level of right‐wing authoritarianism (RWA), the two facets of social dominance orientation (SDO‐Dominance and SDO‐Egalitarianism) and pro‐torture attitudes were measured both in the immediate aftermath (terror salience, N = 152) of the terror attacks in Paris and Brussels and when terrorism was not salient (non‐salience, N = 140). Results showed that RWA and pro‐torture attitudes, bu

Introduction to special issue of "Culture Unbound". Through six original articles, the issue investigates a variety of cultural and scientific discourses and practices that in different ways are related to neuroscience and the brain.

Based on the experience of the author and analyses of citation frequences of papers published in various biological journals, the use of citation counts and journal Impact Factors as a measure of scientific quality is discussed. It is concluded that citation frequency differ not only among biological sub-disciplines such as ecology and taxonomy, but also among taxonomic papers on highly similar toBased on my experience and analyses of citation frequencies of papers published in various biological journals, I discuss the use of citation counts and journal Impact Factors as measures of scientific quality. I conclude that citation frequency differs not only among biological sub-disciplines such as ecology and taxonomy, but also among taxonomic papers on highly similar topics, and that these l

This thesis focuses on the adaptive strategies of daphnids that allows them to maintain stable populations while deal with UV radiation, highlighting the differences in the responses that populations with different evolutionary histories may have.Although exposition to lethal doses in nature is unlikely, sub-lethal UV-B radiation doses may have strong impacts on zooplankton. This work initiates wi

I present higher loop order results for several calculations in Chiral perturbation Theory. 1) Two-loop results at finite volume for hadronic vacuum polarization. 2) A three-loop calculation of the pion mass and decay constant in two-flavour ChPT. For the pion mass all needed auxiliary parameters can be determined from lattice calculations of ππ-scattering. 3) Chiral corrections to neutron-anti-ne

High-throughput sequencing was applied to investigate the mutation/methylation patterns on 1q and gene expression profiles in pediatric B-cell precursor acute lymphoblastic leukemia (BCP ALL) with/without (w/wo) dup(1q). Sequencing of the breakpoint regions and all exons on 1q in seven dup(1q)-positive cases revealed non-synonymous somatic single nucleotide variants (SNVs) in BLZF1, FMN2, KCNT2, L

Special issue of "Culture Unbound". Through six original articles, the issue investigates a variety of cultural and scientific discourses and practices that in different ways are related to neuroscience and the brain.

Cloud computing has emerged as an inexpensive and powerful computing paradigm, to the point that now even applications with hard deadlines are executed in the cloud. It may happen, due to unexpected events, that an application becomes popular and receives a lot of attention and client requests in a short period of time. Provisioning computing capacity for such applications is quite a difficult tas

Objectives. To describe glucocorticoid (GC) use in the SLICC inception cohort and to explore factors associated with GC use. In particular we aimed to assess temporal trends in GC use and to what extent physician-related factors may influence use. Methods. Patients were recruited within 15 months of diagnosis of SLE from 33 centres between 1999 and 2011 and continue to be reviewed annually. Descri