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Cerebral lesions on magnetic resonance imaging, heart disease, and vascular risk factors in subjects without stroke. A population-based study

BACKGROUND AND PURPOSE: To assess the prevalence of asymptomatic abnormalities on magnetic resonance imaging of the brain and their possible relation to hypertension, heart disease, and carotid artery disease, we studied 77 randomly selected subjects (mean age, 65.1 years; range, 36 to 95 years) with no history of focal brain lesions. METHODS: The study protocol included magnetic resonance imaging

Mechanisms of below-ground carbon cycling in subarctic ecosystems

Popular Abstract in Swedish Medeltemperatur på jorden har stigit med ca 0.6 ºC sedan 1900-talets början. Denna ökning beror mycket sannolikt på människans utsläpp av växthusgaser så som t.ex. koldioxid. Under det kommande århundradet räknar man med att jordens medeltemperatur kommer att stiga ytterligare 1.4-5.8 ºC. Både temperaturhöjningen och koldioxidhaltens ökning i atmosfären kan påverka vegeSome components of the below-ground carbon (C) cycle in terrestrial ecosystems are still poorly understood. A better understanding will be necessary to predict adequately the impacts of global change factors on C cycling and storage, especially in high-latitude ecosystems, where much of the C is stored below-ground. In this work some of the mechanisms of the below-ground C cycle in subarctic ecosy

Emotion and Learning - A Computational Model of the Amygdala

Popular Abstract in Swedish Avhandlingen handlar om ett område i hjärnan som kallas amygdala. Detta området är ansvarigt för att lära sig vad man bör tycka om och vad man skall vara rädd för. I avhandlingen diskuteras hur det här området verkar fungera, och hur det arbetar tillsammans med andra områden för att göra sitt jobb. Dessa reaktioner är primitiva känslor; rädsla, lycka och så vidare. AvhaThe amygdala is a small subcortical structure that has long been implicated in the conditioning of fear and other emotions. It is heavily interconnected to a number of both cortical and subcortical structures and is thus well placed to integrate sensory inputs from multiple areas to produce emotional reactions directly as well as influence learning and attention systems. Data suggests that the amy

Trellis source codes based on linear congruential recursions

We evaluate a new class of rate-distortion codes based on simple linear congruential recursions. Codes are demonstrated for the memoryless Uniform, Gaussian, Laplacian and Gamma sources, whose performance often exceeds that so far reported in the literature, including that for TCQ codes. At a source coding rate of one bit per sample the performance at 512 states is 0.24 dB from the Shannon limit f

Role of endogenous glucocorticoid metabolism in human acute pancreatitis*

Objective: This study aimed to observe how levels of total cortisol, calculated free cortisol, corticosteroid-binding globulin, and adrenocorticotropic hormone change during the early course of human acute pancreatitis and to describe how these changes affect the development of pancreatic necrosis. Design and Patients: In a total of 109 consecutive patients with acute pancreatitis (74 with edemato

Stimulation by insulin of a serine kinase in human platelets that phosphorylates and activates the cGMP-inhibited cAMP phosphodiesterase

We previously reported that insulin stimulation of human platelets induces serine phosphorylation and activation of the cGMP-inhibited cAMP phosphodiesterase (cGI-PDE). Here, we describe methods to detect and partially purify an insulin-stimulated cGI-PDE kinase (cGI-PDE ISK) from lysates of platelets incubated with insulin. Incubation of human platelets with 10(-8) M insulin increased cGI-PDE ISK

”Jag kan göra hundra låtar”. Barns musikskapande med digitala verktyg

Popular Abstract in Swedish Bakgrund Denna studie är en undersökning av barns musikskapande med synthesizer och dator. I studien deltog nio barn i åttaårsåldern. Musik utgör en viktig del i barns och ungdomars vardag och den stora exponering för musik som sker i vårt samhälle innebär att ingen är någon musikalisk nybörjare. Det är väl känt att barn kan skapa musik på egen hand, mest är det dock bToday’s children live in a world where music in all its different forms has become a significant factor in their everyday life. From earlier research we know that young children are able to create music by singing and using musical instruments. The present study was undertaken with eight-year-old children in school year 2 in order to investigate the children’s composing and composition processes u

Ultraviolet-B stimulates grana formation in chloroplasts in the African desert plant Dimorphotheca pluvialis

Chloroplasts isolated from a plant species, Dimorphotheca pluvialis Moench (Asteraceae), grown under visible light without supplementary UV-B radiation, have poor grana development. The dominant components in the membrane organizations are doublets and triplets of stroma lamellae. However, such chloroplasts possess the capacity for electron transfer through the whole photosynthetic chain, based on

Fertility in four regions spanning large contrasts in serum levels of widespread persistent organochlorines: a cross-sectional study

BACKGROUND: Persistent organochlorine pollutants (POPs) may interfere with reproductive function but direct evidence in humans is very limited. METHODS: Fertility was examined in four regions with contrasting blood levels of POPs. Pregnant women and their partners in Warsaw (Poland), Kharkiv (Ukraine) and Greenland were consecutively enrolled during antenatal visits. Swedish fishermen and their sp

Characterisation of recombinant isoforms of birch pollen allergen Bet v 1

Three isoforms of the major birch pollen allergen, Bet v, 1 from Betula verrucosa have been expressed as recombinant proteins in E. coli and purified. The immunochemical properties of recombinant isoforms (rBet v 1) differed on immunoblots when compared using Mabs and birch pollen allergic patients serum IgE. 2-D gel analysis showed that recombinant isoforms with different epitope structure can fo