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Advancements and recent explorations of anti-cancer activity of chrysin : from molecular targets to therapeutic perspective

In recent times, there have been notable advancements in comprehending the potential anti-cancer effects of chrysin (CH), a naturally occurring flavonoid compound found abundantly in various plant sources like honey, propolis, and certain fruits and vegetables. This active compound has garnered significant attention due to its promising therapeutic qualities and minimal toxicity. CH’s ability to c

Expiratory and inspiratory resistance and reactance from respiratory oscillometry defining expiratory flow limitation in obstructive lung diseases

Background: Expiratory flow limitation (EFL) during tidal breathing and lung hyperinflation have been identified as major decisive factors for disease status, prognosis and response to therapy in obstructive lung diseases. Aim: To investigate the delta values between expiratory and inspiratory resistance and reactance, measured using respiratory oscillometry and its correlation with air trapping a

Epilogue

In three thematic sections and 18 different chapters, this volume has unpacked and explored the conditions, contexts, and practices of creative work from multiple different perspectives.

Thromboembolic and bleeding risk in cardiac amyloidosis

Cardiac amyloidosis represents a spectrum of conditions characterized by the accumulation of insoluble fibrils, resulting in progressive deposition and myocardial dysfunction. The exact mechanisms contributing to the heightened risk of thromboembolic events and bleeding tendencies in cardiac amyloidosis remain unclear. Proteins such as transthyretin in transthyretin amyloidosis and light chains in

Cytology of thyroid and parathyroid glands in oncology diagnosis – a contemporary review of updates and innovations

Fine needle aspiration (FNA) is widely used in the examination of head and neck lesions and has been considered an important diagnostic tool in the evaluation of thyroid and parathyroid nodules. Thyroid nodules are frequent findings in the general population, although 90-95% of these nodules are benign. FNA plays a crucial role to determine which nodules are at greatest risk of malignancy and whic

Adaptation to fluctuating temperatures across life stages in endotherms

Accelerating rates of climate change have intensified research on thermal adaptation. Increasing temperature fluctuations, a prominent feature of climate change, means that the persistence of many species depends on both heat and cold tolerance across the entire life cycle. In endotherms, research has focused on specific life stages, with changes in thermoregulation across life rarely being examin

Embedded eigenvalues for asymptotically periodic ODE systems

We investigate the persistance of embedded eigenvalues under perturbations of a certain self-adjoint Schrödinger-type differential operator in L2(R; Rn), with an asymptotically periodic potential. The studied perturbations are small and belong to a certain Banach space with a specified decay rate, in particular, a weighted space of continuous matrix valued functions. Our main result is that the se

Between Policy-oriented Criticism and Structural Opposition – Civil Society Advocacy in the Age of Populism

With the wave of right-wing populist parties coming to power and gaining influence in recent years, civil society has been hit by increased ideological resistance from outside. The paper explores how key civil society actors react to policy changes by national governments influenced by right-wing populist parties. The aim is to understand how the rise to power of right-wing populist parties affect

The role of the customer order decoupling point in operations and supply chain management

In the field of operations and supply chain management (OSCM), the customer order decoupling point (CODP) hasi been recognized as an important strategic parameter for roughly 30 years. It is the point in the value chain where forecast-driven material flows get separated from order -driven material flows. Despite its long history in the field, multiple calls for further consideration of the CODP inIn the field of operations and supply chain management (OSCM), the customer order decoupling point (CODP) hasbeen recognized as an important strategic parameter for roughly 30 years. It is the point in the value chain whereforecast-driven material flows get separated from order-driven material flows. Despite its long history in the field,multiple calls for further consideration of the CODP in OSCM

Effects of a Paleolithic diet compared to a diabetes diet on leptin binding inhibition in secondary analysis of a randomised cross-over study

BACKGROUND: Beneficial effects from practising a Paleolithic diet as compared to a diabetes diet on weight, waist circumference, satiety, leptin, HbA1c and glucose control in randomised controlled trial participants with type 2 diabetes could be due to lower leptin resistance. Support for this hypothesis comes from an in vitro experiment that showed that digested wheat gluten, which is excluded fr

Cognitive microfoundations and social interaction dynamics. : The implications of complexity for institutional theory.

This paper investigates the intersection of cognitive sciences and social network theory and its counterpart, the complexity sciences, aiming to shed light on the compatibility and potential integration of these frameworks into institutional theory. Institutional scholars have for long selectively adopted notions linked with the cognitive sciences and complexity sciences, such as the notion of pat

Role of the polyamine transporter PotABCD during biofilm formation by Streptococcus pneumoniae

Streptococcus pneumoniae is a bacterium of great global importance, responsible for more than one million deaths per year. This bacterium is commonly acquired in the first years of life and colonizes the upper respiratory tract asymptomatically by forming biofilms that persist for extended times in the nasopharynx. However, under conditions that alter the bacterial environment, such as viral infec

HAMLET, a human milk protein-lipid complex, modulates amoxicillin induced changes in an ex vivo biofilm model of the oral microbiome.

Challenges from infections caused by biofilms and antimicrobial resistance highlight the need for novel antimicrobials that work in conjunction with antibiotics and minimize resistance risk. In this study we investigated the composite effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells), a human milk protein-lipid complex and amoxicillin on microbial ecology using an ex vivo oral

Biofilm-dispersed pneumococci induce elevated leukocyte and platelet activation

INTRODUCTION: Streptococcus pneumoniae (the pneumococcus) effectively colonizes the human nasopharynx, but can migrate to other host sites, causing infections such as pneumonia and sepsis. Previous studies indicate that pneumococci grown as biofilms have phenotypes of bacteria associated with colonization whereas bacteria released from biofilms in response to changes in the local environment (i.e.

Spatial Machine Learning for Exploring the Variability in Low Height-For-Age From Socioeconomic, Agroecological, and Climate Features in the Northern Province of Rwanda

Childhood stunting is a serious public health concern in Rwanda. Although stunting causes have been documented, we still lack a more in-depth understanding of their local factors at a more detailed geographic level. We cross-sectionally examined 615 height-for-age prevalence observations in the Northern Province of Rwanda, linked with their related covariates, to explore the spatial heterogeneity

No title

A presentation of the results and experiences from a PhD- and excavation project in 1983 concerning the medieval cultural landscape of Bornholm.

Assessing the potential of energy sharing through a shallow geothermal heating and cooling network

Shallow geothermal offers great potential to supply emission-free heating and cooling and has therefore a pivotal role in the transition of heating and cooling networks. This paper presents a novel heating and cooling network with possible geothermal energy sharing between decentralized borefields located at each building level. The system consolidates the benefits of both standalone and centraliz

Image post-processing for SILMAS : structured illumination light sheet microscopy with axial sweeping

In this article, we propose a post-processing scheme for the novel volumetric microscopy technique SILMAS. We demonstrate this scheme on data from an alpha-synuclein transgenic mouse brain. By combining structured illumination and axial sweeping, a SILMAS measurement provides a prerequisite for quantitative data extraction through improved contrast and optical sectioning. However, due to the techn

Testing Quantitative and Qualitative Sex Effects in a National Swedish Twin-Sibling Study of Posttraumatic Stress Disorder

OBJECTIVE: Twin studies have demonstrated that posttraumatic stress disorder (PTSD) is moderately heritable, and the pattern of findings across studies suggests higher heritability in females compared with males. Formal testing of sex differences has yet to be done in twin studies of PTSD. The authors sought to estimate the genetic and environmental contributions to PTSD, and to formally test for