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Instructive cross-talk between neural progenitor cells and gliomas.

Gliomas are the most common primary brain tumors and offer a poor prognosis in patients because of their infiltrative and treatment-resistant nature. The median survival time after diagnosis is approximately 11-12 months. There is a strong need for novel treatment modalities in targeting gliomas, and recent advances use neural progenitor cells as delivery systems for different therapeutic strategi

Analysis of peripheral blood lymphocyte phenotype and function during dexamethazone treatment of progressive multiple sclerosis

Five patients with chronic progressive multiple sclerosis (MS) and three control patients with lumbar disc herniation were treated with dexamethazone during 14 days. The effect on peripheral blood T-cell subsets and on the proliferative response of peripheral blood mononuclear cells (PBMC) to pokeweed mitogen (PWM) and anti-mu antibody was analyzed. Before treatment, the proportion of CD3+ and CD4

Pediatric urinary tract reconstruction using intestine

OBJECTIVE: To analyse the outcome of urinary tract reconstruction in children. MATERIAL AND METHODS: Fifteen children with bladder exstrophy or neurogenic bladder, 4-18 years old, were followed in accordance with a predetermined program for bladder augmentation (13 pat) or continent urinary reservoir (2 pat). The follow-up time was 1.7-6.3 years, median 3.7 years. RESULTS: All were dry, though one

On the Implementation of the Linearly Constrained Minimum Variance Beamformer

The linearly constrained minimum variance (LCMV) method, which allows multiple linear constraints, is an extension of the classical minimum variance distortionless response filter. Depending on the spatial filter length and the desired frequency grid, a direct computation of the resulting spatial beam pattern may be prohibitive. This brief exploits the rich structure of the LCMV expression to find

Why liquid membrane extraction is an attractive alternative in sample preparation

The use of liquid membrane-based extractions is increasingly seen as offering an alternative to conventional sample preparation procedures in analysis of chemical species in both environmental and biological media. In this article, emphasis is placed on the attractiveness of liquid membrane-based extraction techniques to a variety of analytical applications such as speciation of metal ions in biol

Oppositely charged polyelectrolytes. Complex formation and effects of chain asymmetry

The formation of complexes in solutions of oppositely charged polyions has been studied by Monte Carlo simulations. The amount as well as the length, and thus, the absolute charge of one of the polyions have been varied. There is an increasing tendency to form large clusters as the excess of one kind of polyion decreases. When all polyions have the same length, this tendency reaches a maximum near

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This is a study of the form and ideology of the 10th c. world chronicle of Symeon the Logothete.

Essays on Network Effects and Money

Popular Abstract in Swedish Denna avhandling består av fyra separata artiklar. Den gemensamma nämnaren för alla artiklarna är att de behandlar pengar och nätverkseffekter. En vara med nätverkseffekter är en vara där nyttan av varan är beroende av hur många andra individer som använder sig av varan. Ett typexempel i litteraturen är faxmaskiner: ju fler som har en fax, desto större nytta har man av This thesis contains four separate papers in the field of monetary economics. The common basis for all the papers is that they deal with money and network effects in one way or another. Although the common basis is the same in all the articles, different approaches are used: theory, econometrics and history of economic thought. This first essay focuses on the network effect in the use of money an

Quality of life associated with varying degrees of chronic lower limb ischaemia: comparison with a healthy sample

OBJECTIVES: To assess quality of life in patients with varying degrees of ischaemia in comparison with controls, and to determine whether the degree of lower limb ischaemia and sense of coherence were associated with quality of life. MATERIALS AND METHODS: 168 patients, including 93 claudicants and 75 patients with critical ischaemia and 102 controls were studied. Quality of life was assessed usin

Protease activities in the chloroplast capable of cleaving an LHCII N-terminal peptide

Two protease activities of pea chloroplasts, one located in the stroma and the other associated to the thylakoid membrane, are described. Both proteases catalyse the endo-proteolytic cleavage of a peptide corresponding to the N-terminal loop and the first turn in helix-B of light-harvesting complex II (Lhcb1 from pea). The stromal protease cleaves preferentially on the carboxy-side of glutamic aci

Minimizing tissue-material interaction in microsensor for subcutaneous glucose monitoring

A new implantable electrocatalytic glucose sensor for subcutaneous glucose monitoring has been fabricated by immobilizing glucose oxidase on a chemically modified carbon fiber. The sensor was inserted subcutaneously on a male spraguely rat without any incision after dipping the microsensor in the rat's serum for 3 days. The so called "stained" microsensor, operated in the amperometric mode with an

Five Studies in Ethics and Gene Technology

I denna artikel kommenterar jag fem arbeten som alla behandlar modern genteknik ur etisk synpunkt, med hjälp av såväl teologisk som filosofisk etik. Böckerna tas som intäkt för att kortfattat diskutera några etiska problem i anslutning till genteknikens möjligheter, bland annat: Bör vi med genteknik skapa framtida människor med evigt liv? Hur kan vi fatta moraliskt välgrundade beslut som berör fra

Coronary heart disease mortality after 5 years of adjuvant tamoxifen therapy: Results from a randomized trial

From January 1, 1983, through December 31, 1992, a total of 4610 patients entered a randomized trial that compared mortality among patients receiving 2 years of adjuvant tamoxifen therapy with that in patients receiving 5 years of adjuvant tamoxifen therapy, 4175 of whom were recurrence free after 2 years of tamoxifen therapy. Among the 2046 patients randomly assigned to the 5-year group all-cause