To ensure reliability and service availability, nextgeneration networks are expected to rely on automated anomaly detection systems powered by advanced machine learning methods with the capability of handling multi-dimensional data. Such multi-dimensional, heterogeneous data occurs mostly in todays Industrial Internet of Things (IIoT), where real-time detection of anomalies is critical to prevent To ensure reliability and service availability, nextgeneration networks are expected to rely on automated anomaly detection systems powered by advanced machine learning methods with the capability of handling multi-dimensional data. Such multi-dimensional, heterogeneous data occurs mostly in todays Industrial Internet of Things (IIoT), where real-time detection of anomalies is critical to prevent

Therapeutic resistance and recurrence remain core challenges in cancer therapy. How therapy resistance arises is currently not fully understood with tumors surviving via multiple alternative routes. Here, we demonstrate that a subset of cancer cells survives therapeutic stress by entering a transient state characterized by whole-genome doubling. At the onset of the polyploidization program, we ide

Laser frequency stabilization is a necessary component in many modern technologies and physics experiments,providing spectral resolution for spectroscopic investigations, accurate optical clocks for timekeeping and phasestability for interferometry. The limiting factor to the frequency stability of state-of-the-art laser stabilization isfrequency uncertainty as a result from variations in the leng

Obesity is a known risk factor for development of osteoarthritis (OA). Numerical tools like finite-element (FE) models combined with degenerative algorithms have been developed to understand the interplay between OA and obesity. In this study, we aimed to predict knee cartilage degeneration in a cohort of obese adults to investigate the importance of patient-specific information on degeneration pr

The European Spallation Source, ESS, is a neutron research facility under construction in Lund, Southern Sweden. The Facility will produce neutrons by spallation, using a powerful linear accelerator to deliver protons to a tungsten target. In addition to the desired neutron production, a long list of radionuclides will be created as by-products of the nuclear reaction inside the target. The Swedis

The growing interest in lignin valorization in the past decades calls for analytical techniques for lignin characterization, ranging from wet chemistry techniques to highly sophisticated chromatographic and spectroscopic methods. One of the key parameters to consider is the molecular weight profile of lignin, which is routinely determined by size-exclusion chromatography; however, this is by no me

Metal-porphyrins are studied intensively due their potential applications, deriving from the variety of electronic and chemical properties, tunable by selecting metal centers and functional groups. Metalation, de- and trans-metalation processes are fundamental in this sense to investigate both the synthesis and the stability of these molecular building blocks. More specifically, Pd coordination in

Bound states in quantum dots coupled to superconductors can be in a coherent superposition of states with different electron number but with the same fermion parity. Electrostatic gating can tune this superposition to a sweet spot, where the quantum dot has the same mean electric charge independent of its electron-number parity. Here, we propose to encode quantum information in the local fermion p

Air pollution is an environmental factor associated with an increased risk of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, characterized by decreased cognitive abilities and memory. The limited models of sporadic Alzheimer’s disease fail to replicate all pathological hallmarks of the disease, making it challenging to uncover potential environmental causes. Environmentally drive

analys av en grupp målningar av konstnären Fredrik Værslev

A measurement of the Standard Model Higgs boson produced in association with a W or Z boson and decaying into a pair of τ-leptons is presented. This search is based on proton-proton collision data collected at s=13 TeV by the ATLAS experiment at the LHC corresponding to an integrated luminosity of 140 fb−1. For the Higgs boson candidate, only final states with at least one τ-lepton decaying hadron

Background: Regular leisure time physical activity (LTPA) has beneficial health effects in people with spinal cord injury (SCI). Yet, participation in LTPA is low, and little is known about changes many years after injury. Objectives: To determine changes in LTPA in middle-aged and older adults with long-term SCI over six years, investigate associations with gender, age, injury characteristics and

Background: Cardiovascular disease (CVD) is the leading cause of mortality in type 2 diabetes mellitus (T2DM) patients. Shrunken pore syndrome (SPS) is defined as eGFRcystatin C/eGFRcreatinine ratio 0.85, eGFRcystatin C/eGFRcreatinine≤0.85 increased FRS risk (OR = 1.95, 95%CI = 1.18–3.21, p < 0.01). After adjustment for confounding factors, increased eGFRcystatin C/eGFRcreatinine ratio was associa

Background: In light of increasing therapeutic options, risk stratification of advanced cardiac transthyretin amyloidosis (ATTR-CA) is gaining clinical importance to avoid ineffective treatments. Liver stiffness as a marker of hypervolemia and hepatic congestion might predict mortality in advanced ATTR-CA and allow to identify patients at highest risk. Methods: Proven ATTR-CA patients underwent re

Inconel 718 represents a large portion of high-temperature metals in key industries, where the machining-induced surface integrity is quite important. As the different grain size results in various densities of grain boundaries in the deformed area, the surface integrity can be significantly affected. This paper studies the effect of workpiece grain size on machining-induced surface integrity when