It is a human fundamental to desire to be valued, loved and respected - to be significant. Social exclusion induce significance loss which elicits a 'quest for significance' - the search for opportunities to re-gain significance. The present article establishes this relation in a laboratory experiment (N = 71, mean age = 28, SD = 10.42, 65% women, 35% men), showing that socially excluded individua

Background: Survival rates are increasing in patients with prostate cancer, and second primary cancers (SPCs) are becoming more common in these patients. However, the etiology and clinical consequences of SPCs are not well-known. We define the impact of family history on SPC and causes of mortality in these patients. Patients and methods: A nation-wide cohort study based on the Swedish Family-Canc

To assess etiological and clinical consequences of second primary cancers (SPCs) in prostate cancer (PC) patients, we followed newly diagnosed patients to identify men who were diagnosed with a SPC and recorded their causes of death. We used the Swedish Family-Cancer Database to assess relative risks (RRs) and causes of death in SPCs until the year 2015 in patients with a PC diagnosis between 2001

The rapid growth of cities requires effective management of transport demand and restructuring of transport systems to address the needs of growing urban populations in an environmentally, socially and economically sustainable way. In recent years, car sharing has emerged as an alternative to owning cars in cities, which has potential to bring environmental gains and address social considerations.

This paper aims to contribute to the ongoing conceptual development and practical pursuit of resilience, the ability to absorb and respond to shocks, in an agricultural and climate change context. It builds on work that aims to dissolve the nature-society dualism and naturalisation of power relations inherent in systems thinking by developing and extending a framework originally conceived to integ

Statistical information such as death risk estimates is frequently used for illustrating the magnitude of a problem. Such mortality statistics are however easier to evaluate if presented next to an earlier estimate, as the two data points together will illustrate an upward or downward change. How are people influenced by such changes? In seven experiments, participants read mortality statistics (e

Based on his study on the American black ghetto and the French working-class banlieues, Loic Wacquant (2007) conceptualises territorial stigmatisation to capture how the negative perception of relegated urban territories affects their inhabitants and the public policies toward them. Most of the subsequent studies on the topic are done in similar Western post-Fordist and post-colonial settings, and

In cytoplasm, protein γ-tubulin joins with various γ-tubulin complex proteins (GCPs) to form a heterotetramer γ-tubulin small complex (γ-TuSC) that can grow into a ring-shaped structure called the γ-tubulin ring complex (γ-TuRC). Both γ-TuSC and γ-TuRC are required for microtubule nucleation. Recent knowledge on γ-tubulin with regard to its cellular functions beyond participation in its creation o

Purpose: To provide guidelines for all surgical specialists who deal with the open abdomen (OA) or the burst abdomen (BA) in adult patients both on the methods used to close the musculofascial layers of the abdominal wall, and regarding possible materials to be used. Methods: The guidelines were developed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach

This article is concerned with informality-state relations, subaltern politics and citizenship in the context of the urban redevelopment regime. Based on an empirical study of an NGO (SPARC)-mediated resettlement of Project Affected Persons (PAPs) in Mumbai, it explicates the incomplete ‘civilizing of the political society’ which engenders asymmetrical material and leadership enablement and differ

CONTEXT: Pharmacodynamic studies have shown that persistently high platelet reactivity is common in patients with diabetes in spite of clopidogrel treatment. Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes.OBJECTIVES: To estimate the clinical effectiveness associated with clopidogrel treatment after myocardial in

It is easy to get carried away with the rhetoric of solidarity. Rethinking solidarity aims to problematize the way that solidarity has been conceptualized and applied as a governing principle of EU asylum law and policy, in particular as a response to the 2015–2016 ‘refugee crisis’. Navigating through a family of ideas – from Aristotle’s philia, Christian agape, and Roman law to French solidarism,

We prospectively evaluated a combination of fungal biomarkers in adult haematology patients with focus on their clinical utility at different time points during the course of infection. In total, 135 patients were monitored once to twice weekly for serum (1-3)-ß-d-glucan (BG), galactomannan (GM), bis-methyl-gliotoxin and urinary d-arabinitol/l-arabinitol ratio. In all, 13 cases with proven or prob

Background: Oligo-astheno-teratozoospermia is frequently reported in men from infertile couples. Its etiology remains, in the majority of cases, unknown with a variety of factors to contribute to its pathogenesis. The aim of this European Academy of Andrology guideline was to provide an overview of these factors and to discuss available management options. Materials and Methods: PubMed was searche

This chapter explores logistics of participation as a backstage practice of international law’s knowledge production. For its purpose logistics of participation refers to material conditions of possibility of part taking. Taking essay as its form this chapter ties together seemingly dispersed threads in order to reveal how and through what practices scholars of the South are overburdened to partic

Evidence that bird odour can encode social information that can be used in chemical communication is growing, but is restricted to a few taxonomic groups. Among birds, diurnal raptors (i.e. birds from the Accipitriformes and Falconiformes order) have always been considered as mainly relying on their visual abilities. Although they seem to have a functional sense of smell, whether their odour can c

Events can be modeled through a geometric approach, representing event structures in terms of spaces and mappings between spaces. At least two spaces are needed to describe an event, an action space and a result space. In this article, we invoke general mathematical structures in order to develop this geometric perspective. We focus on three cognitive processes that are crucially involved in event