BACKGROUND & AIMS: Systemic glucocorticosteroids (GCSs) have proven efficacy in active ulcerative colitis but cause undesired systemic side effects. Therefore, new GCSs with high topical activity and a high rate of metabolism may be of clinical value in this condition. The aim of this study was to explore the efficacy and safety of the topically acting GCS budesonide in an oral controlled-re

[3H]retinal- or [3h]cholesterol- and [14C]fatty acid-labeled chylomicrons and chylomicron remnants were injected intravenously into normal rats and rats subjected to partial or total obstruction of the bile duct 8 or 48 h earlier. The clearance from plasma of the [3H]retinyl and the [3H]cholesteryl esters in 30-120 min was markedly decreased in rats with total obstruction, and the uptake of 3H by

Views of children and childhood are often closely related to discourses on how children should be treated. This relation between images of the child and discourses on treatment is more or less obvious in for example law, parenthood and education. In this paper I will present the figures of thoughts of children in the Swedish curriculums for the compulsory school, between the years of 1969 and 2011

BACKGROUND: The cervical esophagus is normally lined by squamous epithelium and is usually not exposed to gastroesophageal reflux. The aims of this study were, first, to investigate whether cardiac mucosa can be acquired in the remnant cervical esophagus after esophagectomy and cervical esophagogastrostomy and, second, to characterize this mucosa if present.METHODS: The medical records of 100 pati

The debate around the oxidation states occurring in laboratory-prepared tin-oxide samples has been for a long time an obstacle for an unambiguous assignment of characterization studies performed on such samples. In particular the changes in the Sn core-level energies caused by oxidation - i.e. the chemical shifts - as measured by photoelectron spectroscopy (PES) have been under discussion. The ass

Mutations of Fused in sarcoma (FUS), a ribonucleoprotein involved in RNA metabolism, have been found associated with both familial and sporadic cases of amyotrophic lateral sclerosis (ALS). Notably, besides mutations in the coding sequence, also mutations into the 3′ untranslated region, leading to increased levels of the wild-type protein, have been associated with neuronal death and ALS patholog

This article focuses on the negotiated distinction between commercial and non-commercial spheres of life through the phenomenon of lifestyle entrepreneurship. Lifestyle entrepreneurship is a concept used for a form of self-employment, based on the business owner´s own hobby or lifestyle. The article is based on a study of lifestyle enterprising in the tourism and hospitality industries in southern

Background and aim: Moderate alcohol consumption has been associated with a lower risk of disease severity in non-alcoholic fatty liver disease (NAFLD). It is unclear if this reflects current or lifetime drinking, or can be attributed to confounders such as diet and exercise. We evaluated the impact of lifetime alcohol consumption on fibrosis severity in NAFLD. Methods: We prospectively enrolled 1

Handwritten Bangla numeral recognition has been studied broadly in the last century. This is a very interest subject among the experimenters because of the progression of various pattern recognition algorithms. In this paper, we compare the results of most widely used machine learning method Like Multi Layer Percepton (MLP) and deep learning method like multilayer Convolutional Neural Network (CNN

This chapter proposes a novel offline text dependent writer verification method based on Gray Level Co-occurrence Matrix (GLCM). The method is used to combine the result of Dual Tree Complex Wavelet Transforms (DT-CWT) and GLCM features to enhance the GLCM feature performance. The texture is a very important characteristic, which is used to verify the known writer from unknown writers. We have use

Background: Multimorbidity has already become common in primary care and will be a challenge in the future. Primary care in Sweden participates to a great extent in the care of patients with two severe, chronic conditions: chronic obstructive pulmonary disease (COPD) and heart failure. Both conditions are characterized by high mortality and often coexist. Age, sex, heart failure and other comorbid

Cities around the world are constructing bicycle infrastructure to increase cycling. However, identifying efficient design solutions and determining how bicycle infrastructure planning knowledge can be integrated into comprehensive policy remains a challenge. The objective of this paper is to shed light on the strengths and weaknesses of current bicycle infrastructure planning in both an experienc

Cycling plays an important role in low-carbon transitions. Around the globe, cities are constructing bicycle infrastructure. The city of Copenhagen has a bicycle-friendly infrastructure celebrated for its fine-meshed network. This study documents the spatio-temporal development of Copenhagen’s bicycle infrastructure and explores how the development corresponds to other processes of urban transform