During fracture of membranes loading often produces buckles above and below the crack surface. This changes the stress state surrounding the crack-tip and stresses in the neighbourhood of the crack-tip posses a weaker singularity than r-1/2. As a result, fracture occurs when the crack-tip stress distribution is different as compared with that when buckling is artificially prevented. Therefore the During fracture of membranes loading often produces buckles above and below the cracksurface. This changes the stress state surrounding the crack-tip and stresses in theneighbourhood of the crack-tip posses a weaker singularity than r-1/2. As a result, fractureoccurs when the crack-tip stress distribution is different as compared with that when bucklingis artificially prevented. Therefore the cond

Gastrointestinal (GI) problems constitute an important comorbidity in many patients with autism. Multiple mutations in the neuroligin family of synaptic adhesion molecules are implicated in autism, however whether they are expressed and impact GI function via changes in the enteric nervous system is unknown. We report the GI symptoms of two brothers with autism and an R451C mutation in Nlgn3 encod

Patterns of animal migration and the ecological forces that shape them have been studied for centuries. Yet ecological impacts caused by the migration, such as altered predator–prey interactions and effects on community structure, remain poorly understood. This is to a large extent due to the scarcity of naturally replicated migration systems with negative controls, that is, ecosystems without mig

Background: Abnormal P-wave morphology (PWM) has been associated with a history of atrial fibrillation (AF) in earlier studies. Although lone AF is believed to have substantial genetic basis, studies on associations between single nucleotide polymorphisms (SNP) linked to lone AF and PWM have not been reported. We aimed to assess whether SNPs previously associated with lone AF (rs2200733, rs1337633

The role of the fracture process region during fast fracture is discussed. Reviewed experiments on modern pressure vessel steels show that already at crack tip speeds of one or two hundred mls fracture processes are dominantly brittle. Modelling of the process region is discussed in the light of asymptotic elastic plastic fields and process region autonomy. It is suggested that a fraction of the cThe role of the fracture process region during fast fracture is discussed. Reviewed experiments on modern pressure vessel steels show that already at crack tip speeds of one or two hundred mls fracture processes are dominantly brittle. Modelling of the process region is discussed in the light of asymptotic elastic plastic fields and process region autonomy. It is suggested that a fraction of the c

The Puchezh-Katunki impact structure, 40–80 km in diameter, located ~400 km northeast of Moscow (Russia), has a poorly constrained age between ~164 and 203 Ma (most commonly quoted as 167 ± 3 Ma). Due to its relatively large size, the Puchezh-Katunki structure has been a prime candidate for discussions on the link between hypervelocity impacts and extinction events. Here, we present new 40Ar/39Ar

A combined experimental/numerical method for determination of constitutive parameters in high strain-rate material models is presented. Impact loading, using moderate projectile velocities in combination with small specimens (sub mm) facilitate tensional strain rates in the order of 10(4)-10(5) s(-1). Loading force is measured from one-dimensional wave propagation in a rod using strain gauges and A combined experimental/numerical method for determination of constitutive parameters in high strain-rate material models is presented. Impact loading, using moderate projectile velocities in combination with small specimens (sub mm) facilitate tensional strain rates in the order of 104–105 s−1. Loading force is measured from one-dimensional wave propagation in a rod using strain gauges and deform

The aim of this pilot study was to investigate clinical symptoms during a 10-day benzodiazepine (BZD) taper procedure. Twenty-one BZD-dependent patients attended a fixed 10-day inpatient tapering program. The patients developed mild to moderate withdrawal symptoms. Concomitant codeine dependence and initially high BZD serum levels were associated with a worse prognosis.

Reducing train delays important in many countries, even in those like Japan, where punctuality is already high. There is a clear pattern across the literature that the delays typically occur at stations and are recovered on line sections. Previous work has shown that one explanation for this is that trains interact at stations. When trains have different speeds or stopping patterns, overtakes are Reducing train delays important in many countries, even in those like Japan, where punctuality is already high. There is a clearpattern across the literature that the delays typically occur at stations and are recovered on line sections. Previous work has shownthat one explanation for this is that trains interact at stations. When trains have different speeds or stopping patterns, overtakes areimp