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Objectives: To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression. Method: Data were analyzed from 78 older adults aged 65–88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of th
Mosaic genome-wide paternal uniparental disomy (GW-pUPD) is a rarely recognised disorder. The phenotypic manifestations of multilocus imprinting defects (MLIDs) remain unclear. We report of an apparently non-syndromic infant with severe congenital hyperinsulinism (CHI) and diffuse pancreatic labelling by 18F*-DOPA-PET/CT leading to near-total pancreatectomy. The histology was atypical with pronoun
The social-democratic-inspired “Nordic model”, with its agenda for gender equality, has been an important example for the development of political interventions to transform society but at the same time, it has functioned as an emerging gender normalising and stabilising structure. In the last decade it has also become the focus of antigender movements and ethno-nationalistic parties both as emble
Sedimentary deposits of the Lower Cretaceous Xiagou Formation form the most significant potential hydrocarbon reservoirs in the Qingxi Sag, Jiuquan Basin (NW China). Zircon U-Pb ages of the dated basalts at the top of the Xiagou Formation give an isochron age of 115.6 Ma, and the sedimentation interval of the Xiagou Formation was speculated to range from about 125/124 Ma to 115 Ma based on paleon
The taxonomy, diversity, evolutionary lineages, and stratigraphical distributions of Middle and early Late Triassic conodonts are reviewed and re-evaluated. Twenty-five genera are recognized in the Middle and early Late Triassic, including a new genus cited in open nomenclature. Of these, 24 genera are assigned to two families and seven subfamilies. The family Gondolellidae consists of the subfami
Research on early-life mortality in contemporary and historical populations has shown that infant and child mortality tend to cluster in a limited number of high-mortality families, a phenomenon known as ‘mortality clustering’. This paper is the first to review the literature on the role of the family in early-life mortality. Contemporary results, methodological and theoretical shortfalls, recent
The importance of biodiversity in supporting ecosystem functioning is generally well accepted. However, most evidence comes from small-scale studies, and scaling-up patterns of biodiversity–ecosystem functioning (B-EF) remains challenging, in part because the importance of environmental factors in shaping B-EF relations is poorly understood. Using a forest research platform in which 26 ecosystem f
This article estimates the patterns of socioeconomic inequality in the Barcelona area during the period 1481–1880 using the Marriage License Books from the Diocese of Barcelona, a unique fiscal source that ranged society from nobility, the highest level of payment, to the poor, exempted from taxation. These taxes together with the social status information of each individual allow setting fiscal p
Survival to extreme ages clusters within families. However, identifying genetic loci conferring longevity and low morbidity in such longevous families is challenging. There is debate concerning the survival percentile that best isolates the genetic component in longevity. Here, we use three-generational mortality data from two large datasets, UPDB (US) and LINKS (Netherlands). We study 20,360 unse
A review of existing life cycle assessments on food waste management was made with two main aims. Firstly, to make an overview of the assessments of the global warming potential from the treatment alternatives incineration, landfill, anaerobic digestion and compost in studies reported in literature. Secondly, to identify decisive factors in general and related to system boundary settings in partic
Quite a number of earlier studies have found that the majority of new technology-based firms are spin-offs from existing organizations, usually established in the geographical neighborhood of the parent (Dorfman 1983; Roberts 1991; Saxenian 1994; Sternberg 1996; Keeble 1997; Lindholm Dahlstrand 1997, 2001; Lindholm Dahlstrand and Dahlander 2003). Since established corporations are responsible for
Deepened knowledge on response of biota and ecological processes following fire is essential for a future with warmer climate and more disturbances. In 2014 the first mega-fire (13,100 ha) for at least a century in Scandinavia hit south-central Sweden, in a production forest landscape shaped by clearcutting forestry. Ecological dynamics is followed in >20 projects from universities, authorities an
Epigenetic mechanisms control gene activity and the development of an organism. The epigenome includes DNA methylation, histone modifications, and RNA-mediated processes, and disruption of this balance may cause several pathologies and contribute to obesity and type 2 diabetes (T2D). This Review summarizes epigenetic signatures obtained from human tissues of relevance for metabolism—i.e., adipose
