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Investigating intrinsically derived IgA responses in the intestine of young mice in steady-state and infected conditions

Hålla tarmbakterier i schack hos unga möss Efter födseln exponeras ett spädbarn för den yttre miljön för första gången. Detta innebär exponering för ett stort antal bakterier och virus. Spädbarn är mer benägna att bli infekterade av bakterier och virus än vuxna. Hos vuxna kan antikroppen Immunoglobulin A (IgA) hjälpa till att hålla bakterier och virus i schack genom att omsluta dem och agera som The period after birth, when an infant is initially exposed to vast amounts of environmental and microbial antigens, sets the stage for proper immune system development ensuing lifelong immunity. Simultaneous to this first-time exposure, the nursing mother provides immune protection via antibodies in the breast milk. Secretory Immunoglobulin A, as provided by the mother or produced intrinsically i

The bee as a model to investigate brain and behavioural asymmetries

The honeybee Apis mellifera, with a brain of only 960,000 neurons and the ability to perform sophisticated cognitive tasks, has become an excellent model in life sciences and in particular in cognitive neurosciences. It has been used in our laboratories to investigate brain and behavioural asymmetries, i.e., the different functional specializations of the right and the left sides of the brain. It

Passing on Stories : Collective Memories and the Canon

What are we subjected to when presented with stories about art's past in the context of classrooms or collections? In order to prepare students for a profession in the humanities or in the field of artistic production and reception at large, art history courses in higher education are obliged to provide them with an understanding for the collection of texts, debates or works of art that are consid

Semantic Modelling of Archaeological Excavation Data : A review of the current state of the art and a roadmap of activities

Archaeological data repositories usually manage excavation data collections as project-level entities with restricted capacities to facilitate search or aggregation of excavation data at the sub-collection level (trenches, finds, season reports or excavation diaries etc.). More granular access to excavation data collections would enable layered querying across their informational content. In the p

Brain Fingerprinting Using FMRI Spectral Signatures On High-Resolution Cortical Graphs

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of brain regions. This approach, first, disregards the exquisite spatial detail manifested by fMRI due to working on average regional activities, se

Converging variations and the emergence of horizontal links : To-contraction in American English

The guiding question of this paper is how (horizontal) connections are established when new items enter the network of constructions. It presents a quantitative, corpus-based study of the development of to-contraction (e.g. want to > wanna) in American English since the 19th century. From a plethora of earlier forms, gonna, wanna and gotta emerge, first as representations of phonetic reduction, bu

Antimicrobial peptide therapy for tuberculosis infections

Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. This thesis aims to address this issue by studying

Det skapades delaktighet i det sköna - En studie av Dionysios Areopagitens syn på det skapades delaktighet i det sköna enligt forskarna Brandon Thomas Sammon och Filip Ivanovic

The aim of this thesis is to investigate the theology of beauty in the teachings of Dionysius Areopagita through the works of the researchers Brandon Thomas Sammon and Filip Ivanovic. More specifically the thesis asks the question how Dionysius, according to Sammon and Ivanovic, describes that created creatures can participate in beauty. The study of Dionysius has in the last decades seen a renais

Signaling to the immature brain - Choroid plexus, insulin-like growth factor 1 and extracellular vesicles

I Sverige överlever idag uppemot 80% av de barnen som är födda extremt för tidigt (födda innan graviditetsvecka 28). Dock medföljer en hög sjuklighet, där uppemot 20% av barnen utvecklar olika sjukdomstillstånd såsom blödning i hjärnas hålrum, även kallat intra-ventrikulär hjärnblödning (IVH). Dessutom löper de extremt för tidigt födda barnen en ökad risk att utveckla en intellektuell och neurologExtremely preterm infants (i.e., born below 28 gestational weeks), are at high risk of developing brain morbidities including intraventricular hemorrhage (IVH) and neurodevelopmental impairment. Despite over 50 years of research, there is currently no effective therapy available for preventing IVH. Insulin-like growth factor 1 (IGF-1) plays a pivotal role in perinatal development. Extremely preter

Lichenicolous fungi of southern Scandinavia with particular reference to those associated with Xanthoria calcicola s. lat.

Lichenicolous fungi associated with Xanthoria calcicola s. lat. are studied in southernmost Scandinavia, i.e., Skåne, the southernmost province in Sweden and southern Denmark. Two species, Didymocyrtis slaptoensis and Pyrenochaeta xantho­ riae, are reported as new for the Nordic countries, whereas three species, Didymocyrtis cf. consimilis, Erythricium aurantiacum, and Illosporiopsis christianseni

Measurement of single top-quark production in the s-channel in proton–proton collisions at √s = 13 TeV with the ATLAS detector

A measurement of single top-quark production in the s-channel is performed in proton–proton collisions at a centre-of-mass energy of 13 TeV with the ATLAS detector at the CERN Large Hadron Collider. The dataset corresponds to an integrated luminosity of 139 fb −1. The analysis is performed on events with an electron or muon, missing transverse momentum and exactly two b-tagged jets in the final st

Process Control in Practice

This book covers the most important topics that people working as process control engineers and plant operators will encounter. It focuses on PID control, explains when to use P-, PI-, PD- or PID control as well as PID tuning and includes difficult to control process nonlinearities such as valve stiction or sensor problems. The book also explains advanced control strategies that are necessary when

TESS and CHEOPS discover two warm sub-Neptunes transiting the bright K-dwarf HD 15906

We report the discovery of two warm sub-Neptunes transiting the bright (G = 9.5 mag) K-dwarf HD 15906 (TOI 461, TIC 4646810). This star was observed by the Transiting Exoplanet Survey Satellite (TESS) in sectors 4 and 31, revealing two small transiting planets. The inner planet, HD 15906 b, was detected with an unambiguous period but the outer planet, HD 15906 c, showed only two transits separated