In Saccharomyces cerevisiae, phosphate uptake is mainly dependent on the proton-coupled Pho84 permease under phosphate-limited growth conditions. Phosphate addition causes Pho84-mediated activation of the protein kinase A (PKA) pathway as well as rapid internalization and vacuolar breakdown of Pho84. We show that Pho84 undergoes phosphate-induced phosphorylation and subsequent ubiquitination on am

In 2015 Afghans were the second largest group of asylum seekers in Sweden (and Europe). In this article, I analyze interviews conducted in early 2017 in Scania County with six adult male Afghan asylum seekers, an executive officer at the Swedish Migration Agency, the head of a private asylum seeker camp, and a voluntary worker. I show how the asylum seekers made their way to Sweden not so much thr

Kapitlet skärskådar begreppet ”det civila samhället”. Det beskriver hur det historiskt har tillskrivits olika betydelser, vilket naturligtvis vållat debatt! Kapitlet diskuterar hur civilsamhället och det sociala arbetet förhåller sig till varandra både historiskt och begreppsligt. Den svenska välfärdsstatens utveckling och det civila samhällets roll behandlas både genom att synliggöra hur utveckli

PurposeThe International Labour Organisation (ILO) adopted a new Convention concerning the Prohibition and Immediate Action for the Elimination of the Worst Forms of Child Labour (No. 182) in 1999. The aim of this paper is to analyse the United Nations (UN), ILO, Council of Europe (COE) instruments related to child exploitation and discuss whether child pornography and prostitution are economic cr

The first part of the article is an outline of the nature of sexual harassment, its extent and the growing awareness of it. The second part considers why there was a need for a community initiative and looks at the extent of sexual harassment in the Member States, the consequences of sexual harassment, legal remedies and the impact it has on the community's principles, including health and safety

We apply molecular dynamic simulations to describe [C2mim+][Tf2N-] ionic liquids and its mixtures with solvents confined inside carbon nanopores. Both slit and cylindrical pores are modeled to determine the influence of pore geometry on the electric double layer (EDL) structure and capacitance. Two types of solvents are selected to dilute the ionic liquids in order to establish the effect of solve

The interaction of two confined coaxial jets has been studied using Computational Fluid Dynamics. Annular jet flows over 8 flat blade swirl generator. Numerical simulation uses RNG k- ϵ turbulence model. These models are suitable for turbulent swirl dominated flows. Intermediate swirl injector has been simulated and the flow patterns for non-reactive and reactive cases are contrasted. Low swirling

In this manuscript, a new strategy has been reported for circumscribed covalent attachment of barbed and pointed ends of actin filaments to polystyrene beads. A comparative study of attachment of actin filaments to polystyrene beads was performed by blocking functionally active sites on polystyrene beads with nonionic detergents such as Tween 20, Tween 80 and polyethylene glycol (PEG). Effective b

Transfer integrals for oligos with different bases have been calculated using INDO/Koopman's approximation to unveil the charge transport mechanism in DNA. The sequences, G(A)nG, n = 1, 2, …, 10; G(A)xG(A)yG, x + y = 9; and G(A)xG(A)yG(A)zG, x + y + z = 8, were employed to interpret the Guanine (G) and Adenine(A) hopping. Adenine hopping is found to be faster in G(A)nG sequences with longer Adenin

Establishing diagnostic reference levels (DRLs) in a big country is complicated due to differences in radiological practice between different regions. In 2009-2014, a dose survey was performed in six Russian regions. Based on the results of the survey, preliminary DRLs for conventional X-ray examinations were established on a national level. Additionally, the local authorities were granted the pos

Objective: To elucidate the ultrasound features that can discriminate between benign and malignant ovarian cysts with papillary projections but no other solid component in pregnant women. Methods: Thirty-four women with an ultrasound diagnosis of an ovarian cyst with papillary projections but no other solid component that had been removed surgically during pregnancy were identified from the databa

Objective: The objective of this study was to assess the resource use of treating overactive bladder (OAB) patients in real-world clinical practice and to evaluate whether there is external validity in the treatment of OAB in clinical practice. Materials and methods: The study included 55 patients suffering from OAB and treated with BOTOX® at two Swedish clinics. The study was conducted as an anon

Background Brain injury is reportedly the main cause of death for patients resuscitated after out-of-hospital cardiac arrest (OHCA). However, the majority may actually die following withdrawal of life-sustaining therapy (WLST) with a presumption of poor neurological recovery. We investigated how the protocol for neurological prognostication was used and how related treatment recommendations might

Background Previous viscoelastic haemostatic tests studies have often indicated a hypercoagulative test signal with citrated blood, which could influence clinical decision makings. Purpose The aim of this study was to compare fresh and citrated whole blood using two non-automated viscoelastic ROTEM and Sonoclot tests. Our hypothesis was that citrated blood would demonstrate a hypercoagulative resp

BACKGROUND: Early life risk factors are associated with cardiometabolic disease, but have not been fully studied in atrial fibrillation (AF). There are discordant results from existing studies of birth weight and AF, and the impact of maternal body size, gestational age, placental size, and birth length is unknown.METHODS AND RESULTS: The Helsinki Birth Cohort Study includes 13 345 people born as

One of the major ways in which economic inequality can increase is when the development of wages of ordinary workers trail productivity and GDP growth, meaning that the increasing riches fall in the hand of other social groups (top employees, owners of land and capital). This paper investigates the relationship between wages and GDP in Denmark, Norway and Sweden from 1800 to 1910, using wage serie